Results 51 to 60 of about 1,107,991 (320)
Replicability analysis for genome-wide association studies
, 2014 The paramount importance of replicating associations is well recognized in the genome-wide associaton (GWA) research community, yet methods for assessing replicability of associations are scarce. Published GWA studies often combine separately the results
Heller, Ruth, Yekutieli, Daniel
core +1 more source
GigaScience, 2018 Big datasets, accumulated from biomedical and agronomic studies, provide the potential to identify genes that control complex human diseases and agriculturally important traits through genome-wide association studies (GWAS).
Meng Huang +4 more
semanticscholar +1 more source
Gene-based genome-wide association studies and meta-analyses of conotruncal heart defects. [PDF]
, 2019 Conotruncal heart defects (CTDs) are among the most common and severe groups of congenital heart defects. Despite evidence of an inherited genetic contribution to CTDs, little is known about the specific genes that contribute to the development of CTDs ...
Agopian, AJ +7 more
core +2 more sources
Genome-wide Efficient Mixed Model Analysis for Association Studies
Nature Genetics, 2012 Linear mixed models have attracted considerable attention recently as a powerful and effective tool for accounting for population stratification and relatedness in genetic association tests.
Xiaoping Zhou, M. Stephens
semanticscholar +1 more source
Genome Wide Association Studies Using Multiple-lactation Breeding Value in Holsteins [PDF]
Asian-Australasian Journal of Animal Sciences, 2015 A genome wide association study was conducted using estimated breeding value (EBV) for milk production traits from 1st to 4th lactation. Significant single nucleotide polymorphism (SNP) markers were selected for each trait and the differences were ...
Kwang-Hyun Cho +4 more
doaj +1 more source
Genome-wide association studies in psychiatry: Current perspectives
European Psychiatry, 2021 Body Genome-wide Association Studies in Psychiatry - Current Perspectives Last decade was exciting time for human genetic studies. Genome-wide association studies (GWASs), used to examine the association of genotyped variants across the entire genome and
D. Smajlagic +3 more
doaj +1 more source
Biological networks and epistasis in genome-wide association studies [PDF]
, 2007 Over the last few years, technological improvements have made possible the genotyping of hundreds of thousands of SNPs, enabling whole-genome association studies.
Leif Schauser +3 more
core +3 more sources
bioRxiv, 2018 One in four adults worldwide are either overweight or obese. Epidemiological studies indicate that the location and distribution of excess fat, rather than general adiposity, is most informative for predicting risk of obesity sequellae, including ...
S. Pulit +21 more
semanticscholar +1 more source
Genome-Wide Association Studies of Cancer [PDF]
Journal of Clinical Oncology, 2010 Knowledge of the inherited risk for cancer is an important component of preventive oncology. In addition to well-established syndromes of cancer predisposition, much remains to be discovered about the genetic variation underlying susceptibility to common malignancies.
Zsofia K, Stadler +9 more
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source