Results 51 to 60 of about 833,983 (263)
Genome-Wide Association Studies of Allergic Diseases
Allergology International, 2013 Allergic diseases are complex diseases caused by a combination of genetic and environmental factors. To determine the genetic components of these diseases and to discover the genes and cellular pathways underlying them, a large number of genetic studies ...
Mayumi Tamari +2 more
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Genome-wide association studies in psychiatry: Current perspectives
European Psychiatry, 2021 Body Genome-wide Association Studies in Psychiatry - Current Perspectives Last decade was exciting time for human genetic studies. Genome-wide association studies (GWASs), used to examine the association of genotyped variants across the entire genome and
D. Smajlagic +3 more
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Sequencing-based genome-wide association studies reporting standards
Cell Genomics, 2021 Summary: Genome sequencing has recently become a viable genotyping technology for use in genome-wide association studies (GWASs), offering the potential to analyze a broader range of genome-wide variation, including rare variants.
Aoife McMahon +9 more
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Genome Wide Association Studies Using Multiple-lactation Breeding Value in Holsteins [PDF]
Asian-Australasian Journal of Animal Sciences, 2015 A genome wide association study was conducted using estimated breeding value (EBV) for milk production traits from 1st to 4th lactation. Significant single nucleotide polymorphism (SNP) markers were selected for each trait and the differences were ...
Kwang-Hyun Cho +4 more
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Genome-Wide Association Studies of Cancer [PDF]
Journal of Clinical Oncology, 2010 Knowledge of the inherited risk for cancer is an important component of preventive oncology. In addition to well-established syndromes of cancer predisposition, much remains to be discovered about the genetic variation underlying susceptibility to common malignancies.
Zsofia K, Stadler +9 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
ICAM-1 molecular mechanism and genome wide SNP's association studies
Indian Heart Journal, 2015 Macrophages transformed foam cell formation occurs as a result of leukocyte accumulation mediated through intercellular adhesion molecule 1 (ICAM1), vascular cell adhesion molecule 1 (VCAM1), and E-selectin, secreted by inflamed or damaged endothelium ...
C. Anbarasan +3 more
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Genome-wide association studies: a primer [PDF]
Psychological Medicine, 2009 There have been nearly 400 genome-wide association studies (GWAS) published since 2005. The GWAS approach has been exceptionally successful in identifying common genetic variants that predispose to a variety of complex human diseases and biochemical and anthropometric traits. Although this approach is relatively new, there are many excellent reviews of
Corvin, A. +2 more
openaire +4 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Power analysis for genome-wide association studies
BMC Genetics, 2007 Background Genome-wide association studies are a promising new tool for deciphering the genetics of complex diseases. To choose the proper sample size and genotyping platform for such studies, power calculations that take into account genetic model, tag ...
Klein Robert J
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