Genome-Wide Association Mapping for Stripe Rust Resistance in Pakistani Spring Wheat Genotypes
Plants, 2020 Stripe rust caused by the pathogen Puccinia striiformis f. sp. tritici (Pst) is a major threat for wheat, resulting in low yield and grain quality loss in many countries. Genetic resistance is a prevalent method to combat the disease.
Madiha Habib +3 more
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netgwas: An R Package for Network-Based Genome-Wide Association Studies
, 2019 Graphical models are powerful tools for modeling and making statistical inferences regarding complex associations among variables in multivariate data.
Arends, Danny +2 more
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Pathway analysis comparison using Crohn's disease genome wide association studies
BMC Medical Genomics, 2010 Background The use of biological annotation such as genes and pathways in the analysis of gene expression data has aided the identification of genes for follow-up studies and suggested functional information to uncharacterized genes. Several studies have
Cho Judy +3 more
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scoreInvHap: Inversion genotyping for genome-wide association studies.
PLoS Genetics, 2019 Polymorphic inversions contribute to adaptation and phenotypic variation. However, large multi-centric association studies of inversions remain challenging. We present scoreInvHap, a method to genotype inversions from SNP data for genome-wide association
Carlos Ruiz-Arenas +5 more
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Do we need more genome wide association studies?
Haematologica, 2021 Stephan Menzel
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Genome-Wide Association and Linkage Analysis of Quantitative Traits: Comparison pf Likelihood-Ratio Test and Conditional Score Statistic [PDF]
, 2009 Over the past decade, genetic analysis has shifted from linkage studies, which identify broad regions containing putative trait loci, to genome-wide association studies, which detect the association of a marker with a specific phenotype.
Dupuis, Josée +2 more
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Gene Discovery and Data Sharing in Genome Wide Association Analyses: Lessons Form AIDS Genetic Restriction Genes [PDF]
, 2014 As genome wide association studies plus whole genome sequence analyses for complex human disease determinants are expanding, it seems useful to develop strategies to facilitate large data sharing, rapid replication and validation of provocative ...
Cherkasov, Nikolay +9 more
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SNPLims: a data management system for genome wide association studies
BMC Bioinformatics, 2008 Background Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample.
Salvi Erika +4 more
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Interpreting meta-analyses of genome-wide association studies.
PLoS Genetics, 2012 Meta-analysis is an increasingly popular tool for combining multiple genome-wide association studies in a single analysis to identify associations with small effect sizes.
Buhm Han, Eleazar Eskin
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International Journal of Bipolar Disorders, 2020 Background Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown. Methods We conducted an integrative analysis of genome-wide association study (GWAS) and regulatory SNP (rSNP) annotation datasets ...
Xin Qi +10 more
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