Results 111 to 120 of about 98,968 (210)

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou   +6 more
wiley   +1 more source

Genome-Wide Association Study (GWAS) and Genome-Environment Wide Interaction Study (GEWIS) of Late-Life Depressive Symptoms in Women. [PDF]

open access: bronze, 2015
Erin C. Dunn   +9 more
openalex   +1 more source

Age is not a primary risk factor for ACL injury—A comprehensive review of ACL injury and reinjury risk factors confounded by young patient age

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Revision surgery after anterior cruciate ligament reconstruction (ACL‐R) is hypothesized to be the result of an interplay between factors associated with the anatomy, physiological characteristics and environment of the patient. The multifactorial nature of revision ACL‐R risk is difficult to quantify, and evidence regarding the independent ...
Bálint Zsidai   +10 more
wiley   +1 more source

Genome-wide association studies (GWAS) and their importance in asthma

open access: diamond, 2014
Asunción García‐Sánchez   +7 more
openalex   +2 more sources

Integrated Roles of Systemic Diseases and Serum Biomarkers in the Incidence of Age‐Related Macular Degeneration: The UK Biobank Study

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Background To evaluate the associations of systemic diseases with AMD incidence and explore whether polygenic risk score (PRS) for AMD influences these associations. To assess the impacts of polymorbidities and serum biomarkers on AMD risk. Methods This prospective study of 471156 AMD‐free UK Biobank participants assessed systemic diseases ...
Jun Yu   +9 more
wiley   +1 more source

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