Results 71 to 80 of about 98,968 (210)

Assessing the causal relationship between the plasma proteome and epilepsy: A Mendelian randomization study

Epilepsia Open, EarlyView.
Abstract Objective Understanding the role of plasma proteins in the pathophysiology of epilepsy is crucial for uncovering novel biological mechanisms and therapeutic targets. Mendelian randomization (MR) provides a valuable tool for dissecting potentially causal associations between circulating proteins and disease risk.
Jingfeng Fu, Wei Wu, Shangren Shen
wiley   +1 more source

Prioritization of Osteoporosis-Associated Genome-wide Association Study (GWAS) Single-Nucleotide Polymorphisms (SNPs) Using Epigenomics and Transcriptomics. [PDF]

JBMR Plus, 2021
Zhang X, Deng HW, Shen H, Ehrlich M.
europepmc   +1 more source

Global Stress Responses Identify the Functionally Divergent Regulators Required for Candida auris Commensalism and Pathogenicity

Exploration, EarlyView.
Candida auris is an emerging multidrug‐resistant fungal pathogen that poses a serious global health threat. In our study, we comprehensively delineate both the pan‐genomic and transcriptomic features of C. auris. Intriguingly, our findings reveal an unexpected alkaline pH‐dependent regulation required for C. auris virulence and commensalism mediated by
Chaoyue Xu, Wanxing Xu, Yushun Yuan, Xiaoqing Chen, Ouyang Mo, Zhe Yin, Xinhua Huang, Yuanyuan Wang, Lingfei Hu, Wenwen Xue, Yun Zou, Luyao Zhang, Kunlin Li, Yueru Tian, Jihong Liu, Sichu Xiong, Lei Wu, Yanmei Dong, Guangsheng Chen, Yuping Zhang, Zili Zhou, Ming Guan, Xiaotian Huang, Zhiyi He, Lin Zhong, Lingbing Zeng, Pei Hao, Xiaoqi Zheng, Changbin Chen, Ning‐Ning Liu, Dongsheng Zhou   +30 more
wiley   +1 more source

Bivariate genome-wide association study (GWAS) of body mass index and blood pressure phenotypes in northern Chinese twins. [PDF]

PLoS One, 2021
Li Z, Wang W, Tian X, Duan H, Xu C, Zhang D.   +5 more
europepmc   +1 more source

Genome-wide association study (GWAS) [PDF]

David F Marks
openalex   +1 more source

The GWAS-MAP|ovis platform for aggregation and analysis of genome-wide association study results in sheep

, 2022
A. V. Kirichenko, Alexander S. Zlobin, Tatiana Shashkova, Natalia A Volkova, Б. С. Иолчиев, В. А. Багиров, Pavel M. Borodin, L. С. Karssen, Yakov A. Tsepilov, Yurii S. Aulchenko   +9 more
openalex   +2 more sources

Serum Retinol Levels and Risk of Asthma: Evidence From the NHANES and Mendelian Randomization

Food Frontiers, EarlyView.
The results of cross‐sectional studies and MR analysis support an association between serum retinol and the prevalence of asthma in adults. Higher serum retinol levels may serve as a protective factor against asthma. ABSTRACT Given the ongoing controversy regarding the relationship between serum retinol levels and asthma, this study aims to clarify ...
Xingyang Chen, Meichen Li, Boyang Qu, Yanrong Ao, Hong Gu, Yuan Tian, Yuan Song, Weiwei Cui   +7 more
wiley   +1 more source

Identification of Gene Associated with Sweetness in Corn (Zea mays L.) by Genome-Wide Association Study (GWAS) and Development of a Functional SNP Marker for Predicting Sweet Corn. [PDF]

Plants (Basel), 2021
Ruanjaichon V, Khammona K, Thunnom B, Suriharn K, Kerdsri C, Aesomnuk W, Yongsuwan A, Chaomueang N, Thammapichai P, Arikit S, Wanchana S, Toojinda T.   +11 more
europepmc   +1 more source

72: A Genome Wide Association Study (GWAS) from a global cohort identifies common variants in FSHB and SMAD3 driving spontaneous human dizygotic twinning [PDF]

, 2015
Kjersti M. Aagaard, Hamdi Mbarek, Stacy Steinberg, Dale R. Nyholt, Scott D. Gordon, Michael B. Miller, Allan F. McRae, Jouke‐Jan Hottenga, Felix R. Day, David A. Hinds, Gonneke Willemsen, Eco J. C. de Geus, Gareth Davies, Hilary C. Martin, Cornelis B. Lambalk, Brenda W.J.H. Penninx, Rick Jansen, Kerrie McAloney, Jacqueline M. Vink, Jaakko Kaprio, Robert Plomin, Tim D. Spector, Patrik K. E. Magnusson, Dorret I. Boomsma   +23 more
openalex   +1 more source

Integrative Evidence From Metabolome‐Wide Mendelian Randomization and Animal Models Implicates Tyrosine in Cardiac Hypercontractility and Arrhythmia Risk

Food Frontiers, EarlyView.
Plasma metabolome‐wide Mendelian randomization analysis established a causal link between tyrosine and arrhythmia. GWAS meta‐analysis identified tyrosine‐associated loci linked to cardiovascular risk factors. Animal studies confirmed that oral tyrosine intake modulates heart rhythm via adrenergic signaling activation.
Zhikang Cao, Huiying Liu, Peng Chen, Liyue Chen, Zhixin Chen, Jiaqiang Lin, Zixuan Fu, Zhipeng Li   +7 more
wiley   +1 more source