Rearrangement Events on Circular Genomes
AbstractEarly literature on genome rearrangement modelling views the problem of computing evolutionary distances as an inherently combinatorial one. In particular, attention is given to estimating distances using the minimum number of events required to transform one genome into another.
Joshua Stevenson +2 more
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Impact of Salmonella genome rearrangement on gene expression
In addition to nucleotide variation, many bacteria also undergo changes at a much larger scale via rearrangement of their genome structure (GS) around long repeat sequences.
Emma V. Waters +4 more
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Characterization of gross genome rearrangements in Deinococcus radiodurans recA mutants
Genome stability in radioresistant bacterium Deinococcus radiodurans depends on RecA, the main bacterial recombinase. Without RecA, gross genome rearrangements occur during repair of DNA double-strand breaks. Long repeated (insertion) sequences have been
Jelena Repar +3 more
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Copy number variation, chromosome rearrangement, and their association with recombination during avian evolution [PDF]
Chromosomal rearrangements and copy number variants (CNVs) play key roles in genome evolution and genetic disease; however, the molecular mechanisms underlying these types of structural genomic variation are not fully understood.
Skinner, Benjamin M. +6 more
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Diploid-specific genome stability genes of S. cerevisiae: genomic screen reveals haploidization as an escape from persisting DNA rearrangement stress. [PDF]
Maintaining a stable genome is one of the most important tasks of every living cell and the mechanisms ensuring it are similar in all of them. The events leading to changes in DNA sequence (mutations) in diploid cells occur one to two orders of magnitude
Skoneczna, Adrianna +8 more
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Genome rearrangements with duplications [PDF]
Finding sequences of evolutionary operations that transform one genome into another is a classical problem in comparative genomics. While most of the genome rearrangement algorithms assume that there is exactly one copy of each gene in both genomes, this does not reflect the biological reality very well - most of the studied genomes contain duplicated ...
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Fluorescence in situ hybridization to chromosomes as a tool to understand human and primate genome evolution [PDF]
For the last 15 years molecular cytogenetic techniques have been extensively used to study primate evolution. Molecular probes were helpful to distinguish mammalian chromosomes and chromosome segments on the basis of their DNA content rather than solely ...
Wienberg, Johannes, Wienberg, J.
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Large Chromosomal Rearrangements during a Long-Term Evolution Experiment with
Large-scale rearrangements may be important in evolution because they can alter chromosome organization and gene expression in ways not possible through point mutations.
Colin Raeside +10 more
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Genome rearrangements and phylogeny reconstruction in Yersinia pestis [PDF]
Genome rearrangements have played an important role in the evolution of Yersinia pestis from its progenitor Yersinia pseudotuberculosis. Traditional phylogenetic trees for Y.
Olga O. Bochkareva +7 more
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Rearrangement of Noisy Genomes [PDF]
Measures of distance between genomic maps are inflated by high levels of noise due to incorrectly resolved paralogy and error at the mapping, sequencing and alignment levels. Comparison is also hampered by lack of information on gene orientation and lack gene order.
Chunfang Zheng, David Sankoff
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