Results 21 to 30 of about 103,802 (248)

Combinatorics of Genome Rearrangements [PDF]

, 2009
A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar.
Fertin, Guillaume, Labarre, Anthony, Rusu, Irena, Tannier, Eric, Vialette, Stéphane   +4 more
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Sequence features contributing to chromosomal rearrangements in Neisseria gonorrhoeae. [PDF]

PLoS ONE, 2012
Through whole genome sequence alignments, breakpoints in chromosomal synteny can be identified and the sequence features associated with these determined.
Russell Spencer-Smith, Eldho M Varkey, Mark D Fielder, Lori A S Snyder   +3 more
doaj   +1 more source

Genome rearrangements with duplications [PDF]

BMC Bioinformatics, 2010
Finding sequences of evolutionary operations that transform one genome into another is a classical problem in comparative genomics. While most of the genome rearrangement algorithms assume that there is exactly one copy of each gene in both genomes, this does not reflect the biological reality very well - most of the studied genomes contain duplicated ...
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Competitive repair by naturally dispersed repetitive DNA during non-allelic homologous recombination. [PDF]

PLoS Genetics, 2010
Genome rearrangements often result from non-allelic homologous recombination (NAHR) between repetitive DNA elements dispersed throughout the genome.
Margaret L Hoang, Frederick J Tan, David C Lai, Sue E Celniker, Roger A Hoskins, Maitreya J Dunham, Yixian Zheng, Douglas Koshland   +7 more
doaj   +1 more source

The Interspecific Fungal Hybrid Verticillium longisporum Displays Subgenome-Specific Gene Expression

mBio, 2021
Hybridization is an important evolutionary mechanism that can enable organisms to adapt to environmental challenges. It has previously been shown that the fungal allodiploid species Verticillium longisporum, the causal agent of verticillium stem striping
Jasper R. L. Depotter, Fabian van Beveren, Luis Rodriguez-Moreno, H. Martin Kramer, Edgar A. Chavarro Carrero, Gabriel L. Fiorin, Grardy C. M. van den Berg, Thomas A. Wood, Bart P. H. J. Thomma, Michael F. Seidl   +9 more
doaj   +1 more source

MCMC genome rearrangement [PDF]

Bioinformatics, 2003
Abstract Motivation: As more and more genomes have been sequenced, genomic data is rapidly accumulating. Genome-wide mutations are believed more neutral than local mutations such as substitutions, insertions and deletions, therefore phylogenetic investigations based on inversions, transpositions and inverted transpositions are less ...
openaire   +2 more sources

Insertions and Duplications in the Polyproline Region of the Hepatitis E Virus

Frontiers in Microbiology, 2020
Recombinant strains of hepatitis E virus (HEV) with insertions of human genomic fragments or HEV sequence duplications in the sequence encoding the polyproline region (PPR) were previously described in chronically infected patients.
Sébastien Lhomme, Sébastien Lhomme, Sébastien Lhomme, Florence Nicot, Nicolas Jeanne, Chloé Dimeglio, Alain Roulet, Caroline Lefebvre, Romain Carcenac, Maxime Manno, Martine Dubois, Jean-Marie Peron, Laurent Alric, Nassim Kamar, Nassim Kamar, Nassim Kamar, Florence Abravanel, Florence Abravanel, Florence Abravanel, Jacques Izopet, Jacques Izopet, Jacques Izopet   +21 more
doaj   +1 more source

Ontology for genome comparison and genomic rearrangements

Comparative and Functional Genomics, 2004
AbstractWe present an ontology for describing genomes, genome comparisons, their evolution and biological function. This ontology will support the development of novel genome comparison algorithms and aid the community in discussing genomic evolution. It provides a framework for communication about comparative genomics, and a basis upon which further ...
Flanagan, K, Stevens, R, Pocock, M, Lee, P, Wipat, A   +4 more
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Rearrangement analysis of multiple bacterial genomes

BMC Bioinformatics, 2019
Background Genomes are subjected to rearrangements that change the orientation and ordering of genes during evolution. The most common rearrangements that occur in uni-chromosomal genomes are inversions (or reversals) to adapt to the changing environment.
Mehwish Noureen, Ipputa Tada, Takeshi Kawashima, Masanori Arita   +3 more
doaj   +1 more source

Genome rearrangement algorithms [PDF]

, 2011
With the increasing amount of sequenced genomes, a comparison of species based on these data becomes more and more interesting. In contrast to the classical approach, where only point mutations were considered, genome rearrangement problems ignore small mutations and only consider large-scale mutations that change the gene order on the chromosomes ...
openaire   +1 more source