Results 41 to 50 of about 11,679 (258)

Investigating Potential Chromosomal Rearrangements during Laboratory Culture of Neisseria gonorrhoeae

Microorganisms, 2018
Comparisons of genome sequence data between different strains and isolates of Neisseria spp., such as Neisseria gonorrhoeae, reveal that over the evolutionary history of these organisms, large scale chromosomal rearrangements have occurred.
Russell Spencer-Smith, Simon W. Gould, Madhuri Pulijala, Lori A. S. Snyder   +3 more
doaj   +1 more source

Interstitial deletion 4p15.32p16.1 and complex chromoplexy in a female proband with severe neurodevelopmental delay, growth failure and dysmorphism

Molecular Cytogenetics, 2022
Complex chromosomal rearrangements involve the restructuring of genetic material within a single chromosome or across multiple chromosomes. These events can cause serious human disease by disrupting coding DNA and gene regulatory elements via deletions ...
Dong Li, Alanna Strong, Cuiping Hou, Helen Downes, Amanda Barone Pritchard, Pamela Mazzeo, Elaine H. Zackai, Laura K. Conlin, Hakon Hakonarson   +8 more
doaj   +1 more source

Whole genome comparative studies between chicken and turkey and their implications for avian genome evolution [PDF]

, 2008
BACKGROUND: Comparative genomics is a powerful means of establishing inter-specific relationships between gene function/location and allows insight into genomic rearrangements, conservation and evolutionary phylogeny.
Griffin, D.K., Gaginskaya, E., Robertson, L. B., Völker Martin, Masabanda, Julio S., Burt, D.W., Valérie Fillon, Svetlana Deryusheva, Robertson Lindsay B, Griffin Darren K, Fillon, V., Masabanda, J. S., Martin Völker, Richard Talbot, Crooijmans, Richard P.M.A., Darren K Griffin, Gaginskaya, Elena, Vignal Alain, Martien AM Groenen, Crooijmans, Richard P. M. A., Dave W Burt, Groenen, M.A.M., Burt Dave W, Robertson, L.B., Griffin, D. K., Burt, D. W., Helen G Tempest, Carre, Wilfrid, Vignal, Alain, Julio S Masabanda, Crooijmans, R.P.M.A., Burt, Dave W, Tempest, H.G., Groenen, Martien A. M., Griffin, Darren K., Deryusheva, Svetlana, Waddington David, Talbot, Richard, Waddington, D., Robertson, Lindsay B., Robertson, Lindsay, Carré Wilfrid, Masabanda, Julio S, Groenen, Martien AM, Tempest, Helen G., Gaginskaya Elena, Fillon Valérie, Burt, Dave W., Waddington, David, Tempest, H. G., Groenen Martien AM, Fillon, Valerie, Lindsay B Robertson, Talbot Richard, Crooijmans, R. P., Deryusheva, S., Elena Gaginskaya, Masabanda Julio S, Tempest Helen G, Volker, Martin, Crooijmans, Richard PMA, Groenen, M. A., David Waddington, Deryusheva Svetlana, Talbot, R., Wilfrid Carré, Richard PMA Crooijmans, Masabanda, J.S., Vignal, A., Alain Vignal, Burt, David W., Crooijmans Richard PMA, Volker, M., Carre, W.   +73 more
core   +1 more source

Intergenomic rearrangements after polyploidization of Kengyilia thoroldiana (Poaceae: Triticeae) affected by environmental factors. [PDF]

PLoS ONE, 2012
Polyploidization is a major evolutionary process. Approximately 70-75% species of Triticeae (Poaceae) are polyploids, involving 23 genomes. To investigate intergenomic rearrangements after polyploidization of Triticeae species and to determine the ...
Qiuxia Wang, Huitao Liu, Ainong Gao, Xinming Yang, Weihua Liu, Xiuquan Li, Lihui Li   +6 more
doaj   +1 more source

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

, 2011
: BACKGROUND: Structural rearrangements form a major class of somatic variation in cancer genomes. Local chromosome shattering, termed chromothripsis, is a mechanism proposed to be the cause of clustered chromosomal rearrangements and was recently ...
Cuppen, E., Marlous Hoogstraat, Lieshout, S., van, Stef van Lieshout, Ivo Renkens, van Lieshout, S., Roosmalen van, M., Belt van de, J., Marco Koudijs, Hoogstraat, M., Voest, E.E., Koudijs, M.J., Isaac J Nijman, Edwin Cuppen, van Roosmalen, M., Ruben van 't Slot, José van de Belt, Masoumeh Tavakoli-Yaraki, Wijnand Roessingh, Vermaat, J.S., Slot, R., van 't, Nijman, I.J., Kloosterman, W.P., Lieshout van, S., Emile Voest, Renkens, I., Oscar Paling, Joost S Vermaat, Vermaat, J.E., Wigard P Kloosterman, Van't Slot, R., Belt, J., van de, van de Belt, J., Roessingh, W., Paling, O., Slot Van't, R., Guryev, V., Roosmalen, M.J., van, Tavakoli-Yaraki, M., Victor Guryev, Markus J van Roosmalen   +40 more
core   +1 more source

Sorting by Multi-Cut Rearrangements

Algorithms, 2021
A multi-cut rearrangement of a string S is a string S′ obtained from S by an operation called k-cut rearrangement, that consists of (1) cutting S at a given number k of places in S, making S the concatenated string X1·X2·X3·…·Xk·Xk+1, where X1 and Xk+1 ...
Laurent Bulteau, Guillaume Fertin, Géraldine Jean, Christian Komusiewicz   +3 more
doaj   +1 more source

A novel custom high density-comparative genomic hybridization array detects common rearrangements as well as deep intronic mutations in dystrophinopathies [PDF]

, 2008
Background: The commonest pathogenic DMD changes are intragenic deletions/duplications which make up to 78% of all cases and point mutations (roughly 20%) detectable through direct sequencing.
McCauley, J, A. Ferlini, Martoni Elena, Cecilia Trabanelli, Ashton Emma, Ciccone, R, S. Abbs, Elena Bassi, Venturoli A, F. Muntoni, Emma Ashton, Rimessi P, Brioschi S, Neri M, Venturoli, A, Elena Martoni, Bovolenta, M, McCauley J, M. Neri, Trabanelli Cecilia, Maria S Falzarano, McCauley Joanne, Ferlini Alessandra, Muntoni Francesco, J. McCauley, Fabris M, CICCONE, ROBERTO, Merlini Luciano, Gualandi, F, Shu Yau, Yau S, Martoni, E, Paola Rimessi, Yau Shu, M. S. Falzarano, E. Martoni, Venturoli Anna, Ferlini, A, Luciano Merlini, Merlini L, Brioschi Simona, Spitali, P, Falzarano Maria S, Ciccone Roberto, Martoni E, Anna Venturoli, Spitali P, Abbs S, Marina Fabris, Sergio Fini, Abbs, S, Bassi E, Ferlini A., Ashton E, E. Bassi, Merlini, L, C. Trabanelli, Fini Sergio, M. Bovolenta, Roberto Ciccone, Fini, S, Yau, S, M. Fabris, Ashton, E, Alessandra Ferlini, L. Merlini, S. Fini, E. Ashton, Muntoni, F, Rimessi, P, Simona Brioschi, P. Rimessi, F. Gualandi, Francesco Muntoni, Brioschi, S, Neri, M, Matteo Bovolenta, Marcella Neri, Gualandi F, Bassi, E, Falzarano MS, Pietro Spitali, P. Spitali, S. Yau, Fabris, M, Abbs Stephen, S. Brioschi, Trabanelli C, Falzarano, MS, Fabris Marina, A. Venturoli, Spitali Pietro, Stephen Abbs, Francesca Gualandi, Bassi Elena, Muntoni F, Trabanelli, C, Bovolenta Matteo, Bovolenta M, Gualandi Francesca, Joanne McCauley, Neri Marcella, Rimessi Paola, Fini S   +103 more
core   +1 more source

Genomic rearrangements in prostate cancer [PDF]

Current Opinion in Urology, 2015
Genomic instability is a fundamental feature of human cancer, leading to the activation of oncogenes and inactivation of tumor suppressors. In prostate cancer (PCA), structural genomic rearrangements, resulting in gene fusions, amplifications, and deletions, are a critical mechanism effecting these alterations.
Christopher E, Barbieri, Mark A, Rubin
openaire   +2 more sources

Analyzing Genome Rearrangements in Saccharomyces cerevisiae [PDF]

, 2017
Genome rearrangements underlie different human diseases including many cancers. Determining the rates at which genome rearrangements arise and isolating unique, independent genome rearrangements is critical to understanding the genes and pathways that ...
Putnam, Christopher D, Christopher D. Putnam, Richard D. Kolodner, Anjana Srivatsan, Kolodner, Richard D, Srivatsan, Anjana   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source