Results 31 to 40 of about 103,802 (248)
Inversions maintain differences between migratory phenotypes of a songbird
Nature Communications, 2023 Rearrangements in the genome are important for local adaptation and speciation but are often difficult to identify reliably. Here the authors show that rearrangements underlie large chromosome regions that separate differentially migratory willow ...
Max Lundberg +3 more
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BMC Genomics, 2018 Background The ability of bacteria to acquire resistance to antibiotics relies to a large extent on their capacity for genome modification. Prokaryotic genomes are highly plastic and can utilize horizontal gene transfer, point mutations, and gene ...
Marloes Hoeksema +4 more
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Microorganisms, 2018 Comparisons of genome sequence data between different strains and isolates of Neisseria spp., such as Neisseria gonorrhoeae, reveal that over the evolutionary history of these organisms, large scale chromosomal rearrangements have occurred.
Russell Spencer-Smith +3 more
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Molecular Cytogenetics, 2022 Complex chromosomal rearrangements involve the restructuring of genetic material within a single chromosome or across multiple chromosomes. These events can cause serious human disease by disrupting coding DNA and gene regulatory elements via deletions ...
Dong Li +8 more
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Intergenomic rearrangements after polyploidization of Kengyilia thoroldiana (Poaceae: Triticeae) affected by environmental factors. [PDF]
PLoS ONE, 2012 Polyploidization is a major evolutionary process. Approximately 70-75% species of Triticeae (Poaceae) are polyploids, involving 23 genomes. To investigate intergenomic rearrangements after polyploidization of Triticeae species and to determine the ...
Qiuxia Wang +6 more
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Sorting by Multi-Cut Rearrangements
Algorithms, 2021 A multi-cut rearrangement of a string S is a string S′ obtained from S by an operation called k-cut rearrangement, that consists of (1) cutting S at a given number k of places in S, making S the concatenated string X1·X2·X3·…·Xk·Xk+1, where X1 and Xk+1 ...
Laurent Bulteau +3 more
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Genomic rearrangements in prostate cancer [PDF]
Current Opinion in Urology, 2015 Genomic instability is a fundamental feature of human cancer, leading to the activation of oncogenes and inactivation of tumor suppressors. In prostate cancer (PCA), structural genomic rearrangements, resulting in gene fusions, amplifications, and deletions, are a critical mechanism effecting these alterations.
Christopher E, Barbieri, Mark A, Rubin
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source
Implicit Transpositions in DCJ Scenarios
Frontiers in Genetics, 2017 Genome rearrangements are large-scale evolutionary events that shuffle genomic architectures. The minimal number of such events between two genomes is often used in phylogenomic studies to measure the evolutionary distance between the genomes. Double-Cut-
Pavel Avdeyev +2 more
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Recombination-mediated genome rearrangements
Current Opinion in Genetics & Development, 2021 Homologous recombination (HR) is a universal DNA double-strand break (DSB) repair pathway that uses an intact DNA molecule as a template. Signature HR reactions are homology search and DNA strand invasion catalyzed by the prototypical RecA-ssDNA filament (Rad51 and Dmc1 in eukaryotes), which produces heteroduplex DNA-containing joint molecules (JMs ...
Savocco, Jérôme, Piazza, Aurèle
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