Results 21 to 30 of about 24,640 (259)

ABySS-Explorer: Visualizing Genome Sequence Assemblies [PDF]

IEEE Transactions on Visualization and Computer Graphics, 2009
One bottleneck in large-scale genome sequencing projects is reconstructing the full genome sequence from the short subsequences produced by current technologies. The final stages of the genome assembly process inevitably require manual inspection of data inconsistencies and could be greatly aided by visualization.
Cydney B. Nielsen, Shaun D. Jackman, Inanç Birol, Steven J. M. Jones   +3 more
openaire   +3 more sources

Development and validation of an rDNA operon based primer walking strategy applicable to de novo bacterial genome finishing.

Frontiers in Microbiology, 2015
Advances in sequencing technology have drastically increased the depth and feasibility of bacterial genome sequencing. However, little information is available that details the specific techniques and procedures employed during genome sequencing despite ...
Alexander William Eastman, Alexander William Eastman, Ze-Chun eYuan, Ze-Chun eYuan   +3 more
doaj   +1 more source

Phylogenetic Comparative Assembly [PDF]

, 2009
Husemann P, Stoye J. Phylogenetic Comparative Assembly. Algorithms for Molecular Biology. 2010;5(1): 3.BACKGROUND:Recent high throughput sequencing technologies are capable of generating a huge amount of data for bacterial genome sequencing projects ...
Stoye Jens, Husemann Peter, Jens Stoye, Husemann, Peter, Stoye, Jens ; https://orcid.org/, Peter Husemann   +5 more
core   +1 more source

A pilot study for channel catfish whole genome sequencing and de novo assembly

BMC Genomics, 2011
Background Recent advances in next-generation sequencing technologies have drastically increased throughput and significantly reduced sequencing costs.
Jiang Yanliang, Lu Jianguo, Peatman Eric, Kucuktas Huseyin, Liu Shikai, Wang Shaolin, Sun Fanyue, Liu Zhanjiang   +7 more
doaj   +1 more source

Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts. [PDF]

, 2014
Plasmodium falciparum causes most human malaria deaths, having prehistorically evolved from parasites of African Great Apes. Here we explore the genomic basis of P.
Conway, David J, Conway, David J., Ollomo, Benjamin, Ollomo, B., Böhme, Ulrike, Berriman, Matthew, Thomas, A. W., Bohme, U., Rayner, Julian C., Otto, Thomas D, Rayner, Julian C, Otto, Thomas D., Spottiswoode, N., Newbold, C., Otto, T. D., Pain, A., Pain, Arnab, Thomas, Alan W., Rayner, J. C., Berriman, M., Sanders, M., Conway, D. J., Renaud, F., Sanders, Mandy, Quail, Michael, Renaud, François, Quail, M., Thomas, Alan W, Spottiswoode, Natasha, Newbold, Chris, Prugnolle, Franck   +30 more
core   +1 more source

Fully Phased Sequence of a Diploid Human Genome Determined de Novo from the DNA of a Single Individual

G3: Genes, Genomes, Genetics, 2020
In recent years, improved sequencing technology and computational tools have made de novo genome assembly more accessible. Many approaches, however, generate either an unphased or only partially resolved representation of a diploid genome, in which ...
llya Soifer, Nicole L. Fong, Nelda Yi, Andrea T. Ireland, Irene Lam, Matthew Sooknah, Jonathan S. Paw, Paul Peluso, Gregory T. Concepcion, David Rank, Alex R. Hastie, Vladimir Jojic, J. Graham Ruby, David Botstein, Margaret A. Roy   +14 more
doaj   +1 more source

Comparison of ONT and CCS sequencing technologies on the polyploid genome of a medicinal plant showed that high error rate of ONT reads are not suitable for self-correction

Chinese Medicine, 2022
Background Many medicinal plants are known for their complex genomes with high ploidy, heterozygosity, and repetitive content which pose severe challenges for genome sequencing of those species. Long reads from Oxford nanopore sequencing technology (ONT)
Peng Zeng, Zunzhe Tian, Yuwei Han, Weixiong Zhang, Tinggan Zhou, Yingmei Peng, Hao Hu, Jing Cai   +7 more
doaj   +1 more source

The development and characterization of a 60K SNP chip for chicken [PDF]

, 2011
Background In livestock species like the chicken, high throughput single nucleotide polymorphism (SNP) genotyping assays are increasingly being used for whole genome association studies and as a tool in breeding (referred to as genomic selection).
Vereijken, Addie, Wesley C Warren, William M Muir, Hillier LaDeana W, LaDeana W Hillier, Zare Yalda, Groenen, Martien AM, Hillier, LaDeana W, Hans H Cheng, Groenen, Martin AM, Vereijken Addie, Muir William M, Zare, Yalda, Cheng, Hans H, Groenen Martien AM, Megens, H.J.W.C., Cheng Hans H, Megens Hendrik-Jan, Ron Okimoto, Vereijken, A., Muir, W.M., Martien AM Groenen, Groenen, M.A.M., Hendrik-Jan Megens, Warren Wesley C, Crooijmans, Richard PMA, Yalda Zare, Warren, W.C., Warren, Wesley C, Zare, Y., Okimoto Ron, Cheng, H.H., Richard PMA Crooijmans, Addie Vereijken, Hillier, L.W., Okimoto, Ron, Muir, Williams M, Crooijmans, R.P.M.A., Okimoto, R., Megens, Hendrik-Jan, Muir, William M, Crooijmans Richard PMA   +41 more
core   +2 more sources

LDscaff: LD-based scaffolding of de novo genome assemblies

BMC Bioinformatics, 2020
Background Genome assembly is fundamental for de novo genome analysis. Hybrid assembly, utilizing various sequencing technologies increases both contiguity and accuracy.
Zicheng Zhao, Yingxiao Zhou, Shuai Wang, Xiuqing Zhang, Changfa Wang, Shuaicheng Li   +5 more
doaj   +1 more source

Genome assembly of Vitis rotundifolia Michx. using third-generation sequencing (Oxford Nanopore Technologies)

Труды по прикладной ботанике, генетике и селекции, 2021
The immune North American grapevine species Vitis rotundifolia Michaux (subgen. Muscadinia Planch.) is regarded as a potential donor of disease resistance genes, withstanding such dangerous diseases of grapes as powdery and downy mildews.
M. M. Agakhanov, E. A. Grigoreva, E. K. Potokina, P. S. Ulianich, Y. V. Ukhatova   +4 more
doaj   +1 more source