Results 11 to 20 of about 2,120,585 (276)
Characterising genome architectures using genome decomposition analysis [PDF]
BMC Genomics, 2021 AbstractGenome architecture describes how genes and other features are arranged in genomes. These arrangements reflect the evolutionary pressures on genomes and underlie biological processes such as chromosomal segregation and the regulation of gene expression.
Eerik Aunin +2 more
openaire +4 more sources
Microbial genomic taxonomy [PDF]
, 2013 A need for a genomic species definition is emerging from several independent studies worldwide. In this commentary paper, we discuss recent studies on the genomic taxonomy of diverse microbial groups and a unified species definition based on genomics ...
Chimetto, Luciane +5 more
core +3 more sources
EXPLoRA-web: linkage analysis of quantitative trait loci using bulk segregant analysis [PDF]
, 2016 Identification of genomic regions associated with a phenotype of interest is a fundamental step toward solving questions in biology and improving industrial research.
Duitama, Jorge +2 more
core +3 more sources
ERβ and NFκB—Modulators of Zearalenone-Induced Oxidative Stress in Human Prostate Cancer Cells
Toxins, 2020 Nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) is commonly expressed in prostate cancer (PCa) cells and is associated with increased proliferation, metastases and androgen independence.
Karolina Kowalska +4 more
doaj +1 more source
An investigation into inter- and intragenomic variations of graphic genomic signatures [PDF]
, 2015 We provide, on an extensive dataset and using several different distances, confirmation of the hypothesis that CGR patterns are preserved along a genomic DNA sequence, and are different for DNA sequences originating from genomes of different species ...
Karamichalis, Rallis +3 more
core +3 more sources
Joint and individual analysis of breast cancer histologic images and genomic covariates [PDF]
, 2020 A key challenge in modern data analysis is understanding connections between complex and differing modalities of data. For example, two of the main approaches to the study of breast cancer are histopathology (analyzing visual characteristics of tumors ...
Calhoun, Benjamin C. +10 more
core +3 more sources
Frontiers in Public Health, 2020 The population structure of human isolates of Listeria monocytogenes in Emilia-Romagna, Italy, from 2012 to 2018 was investigated with the aim of evaluating the presence of genomic clusters indicative of possible outbreaks, the proportion of cluster ...
Erika Scaltriti +6 more
doaj +1 more source
Clinical Case Reports, 2019 Recognition of a de novo mutation in NR4A2 associated with a neurodevelopmental phenotype reinforces its role in 2q23q24 microdeletion syndrome. Using the proband WES data and the probability of loss‐of‐function intolerance index (pLi) set at 1.0 ...
Luiza L. P. Ramos +7 more
doaj +1 more source
2b-RAD genotyping for population genomic studies of Chagas disease vectors: Rhodnius ecuadoriensis in Ecuador [PDF]
, 2017 Background: Rhodnius ecuadoriensis is the main triatomine vector of Chagas disease, American trypanosomiasis, in Southern Ecuador and Northern Peru.
Andersson, Björn +10 more
core +4 more sources
Removing batch effects for prediction problems with frozen surrogate variable analysis [PDF]
, 2013 Batch effects are responsible for the failure of promising genomic prognos- tic signatures, major ambiguities in published genomic results, and retractions of widely-publicized findings.
Bravo, Héctor Corrada +2 more
core +3 more sources