Results 31 to 40 of about 56,311 (230)

Parent-of-origin effects cause genetic variation in pig performance traits

Animal, 2010
In order to assess the relative importance of genomic imprinting for the genetic variation of traits economically relevant for pork production, a data set containing 21 209 records from Large White pigs was analysed.
N. Neugebauer, H. Luther, N. Reinsch
doaj   +1 more source

The Evolutionary Advantage in Mammals of the Complementary Monoallelic Expression Mechanism of Genomic Imprinting and Its Emergence From a Defense Against the Insertion Into the Host Genome

Frontiers in Genetics, 2022
In viviparous mammals, genomic imprinting regulates parent-of-origin-specific monoallelic expression of paternally and maternally expressed imprinted genes (PEGs and MEGs) in a region-specific manner.
Tomoko Kaneko-Ishino, Fumitoshi Ishino
doaj   +1 more source

Imprinting and its disorders in evolutionary perspective

Acta Medica Lituanica, 2014
Bacground. Genomic imprinting is one of the best-studied epigenetic phenomena involving all the main epigenetic processes. Recent investigations led to a huge expansion of knowledge in this field and changed some established paradigms regarding ...
Birutė Tumienė, Algirdas Utkus, Vaidutis Kučinskas   +2 more
doaj   +1 more source

Placental imprinting: Emerging mechanisms and functions.

PLoS Genetics, 2020
As the maternal-foetal interface, the placenta is essential for the establishment and progression of healthy pregnancy, regulating both foetal growth and maternal adaptation to pregnancy.
Courtney W Hanna
doaj   +1 more source

Zfp57 mutant ES cell lines directly derived from blastocysts

Stem Cell Research, 2016
Zfp57 is a master regulator of genomic imprinting in mouse embryos. To further test its functions, we have derived multiple Zfp57 mutant ES clones directly from mouse blastocysts.
Ho-Tak Lau, Lizhi Liu, Xiajun Li
doaj   +1 more source

Technical advances contribute to the study of genomic imprinting.

PLoS Genetics, 2019
Genomic imprinting in mammals was discovered over 30 years ago through elegant embryological and genetic experiments in mice. Imprinted genes show a monoallelic and parent of origin-specific expression pattern; the development of techniques that can ...
Yuanyuan Li, Jinsong Li
doaj   +1 more source

Genomic imprinting and genetic effects on muscle traits in mice

BMC Genomics, 2012
Background Genomic imprinting refers to parent-of-origin dependent gene expression caused by differential DNA methylation of the paternally and maternally derived alleles.
Kärst Stefan, Vahdati Ali R, Brockmann Gudrun A, Hager Reinmar   +3 more
doaj   +1 more source

Epigenetic modifications potentially controlling the allelic expression of imprinted genes in sunflower endosperm

BMC Plant Biology, 2021
Background Genomic imprinting is an epigenetic phenomenon mainly occurs in endosperm of flowering plants. Genome-wide identification of imprinted genes have been completed in several dicot Cruciferous plant and monocot crops.
Zhichao Zhang, Shuai Yu, Jing Li, Yanbin Zhu, Siqi Jiang, Haoran Xia, Yue Zhou, Daqiu Sun, Meiling Liu, Cong Li, Yanshu Zhu, Yanye Ruan, Xiaomei Dong   +12 more
doaj   +1 more source

Sex dependent imprinting effects on complex traits in mice

BMC Evolutionary Biology, 2008
Background Genomic imprinting is an epigenetic source of variation in quantitative traits that results from monoallelic gene expression, where commonly either only the paternally- or the maternally-derived allele is expressed.
Leamy Larry J, Cheverud James M, Hager Reinmar, Wolf Jason B   +3 more
doaj   +1 more source

The Role of Long Non-coding RNAs in Human Imprinting Disorders: Prospective Therapeutic Targets

Frontiers in Cell and Developmental Biology, 2021
Genomic imprinting is a term used for an intergenerational epigenetic inheritance and involves a subset of genes expressed in a parent-of-origin-dependent way.
Tingxuan Wang, Jianjian Li, Liuyi Yang, Manyin Wu, Qing Ma   +4 more
doaj   +1 more source