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Genetic biomarkers and individual susceptibility in healthcare workers exposed to waste anesthetic gases: a systematic review and meta-analysis [PDF]
Frontiers in MedicineBackgroundFrom a precision medicine perspective, this systematic review and meta-analysis synthesizes evidence on the genotoxic effects of waste anesthetic gases (WAGs) in healthcare workers.
Bin Li, Huadong Zhu, Yueping Ge
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Genotoxic exposures to volatile organic compounds in golden retrievers with and without multicentric lymphoma [PDF]
Frontiers in Veterinary ScienceCanine multicentric lymphoma is a common cancer in dogs with poor long-term outcomes. In people, non-Hodgkin lymphoma is associated with volatile organic compounds (VOCs), but this risk is not clear for lymphoma in dogs.
Ashleigh N. Tindle +4 more
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Urothelial genotoxicity of household chemicals in healthy canine urinary bladder organoids relative to observed urinary exposures in pet dogs [PDF]
Frontiers in Veterinary ScienceIntroductionUrothelial carcinoma (UC) in pet dogs closely resembles human muscle-invasive UC, which is associated with environmental chemical carcinogens.
Hannah M. Peterson +8 more
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Genetic Damage to Human Lymphocytes Induced by Contaminated Water in Populations Surrounding Lake Chapala and the Santiago River, Jalisco, México [PDF]
ToxicsPolluted water in the Chapala–Santiago basin (CSB) contains several genotoxic substances that present risks to human health, particularly among residents of communities surrounding Lake Chapala and the Santiago River, where a high prevalence of cancer ...
Mónica Reynoso-Silva +9 more
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Journal of Occupational Medicine and Toxicology, 2022 Background Several drugs for human use possess genotoxic properties as a necessary consequence of their intended therapeutic effect (e.g. antineoplastics).
Johannes Gerding +3 more
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Frontiers in Toxicology, 2023 Carcinogenic chemicals, or their metabolites, can be classified as genotoxic or non-genotoxic carcinogens (NGTxCs). Genotoxic compounds induce DNA damage, which can be detected by an established in vitro and in vivo battery of genotoxicity assays.
Marc Audebert +33 more
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Toxics, 2021 Beside partial coverage in three reviews so far (1994, 2009, 2019), there is no review on genotoxic studies dealing with mercury (Hg) and human exposure using the most usual genotoxic assays: sister chromatid exchanges (SCE), chromosomal aberrations (CA),
Juana Sánchez-Alarcón +5 more
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Cell Death and Disease, 2021 Stem and progenitor cells are the main mediators of tissue renewal and repair, both under homeostatic conditions and in response to physiological stress and injury. Hematopoietic system is responsible for the regeneration of blood and immune cells and is
Lin Tze Tung +5 more
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Revista Ambiente & Água, 2014 Tradescantia pallida var. purpurea cuttings with flower buds are utilized in bioassays to diagnose genotoxic effects of water. The literature describes different substances used to adapt and recover the cuttings before and after exposure to water samples
Mara Betânia Brizola Cassanego +5 more
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Biomedical Papers, 2016 Aims: Goeckerman therapy is based on combined exposure to UV radiation (UVA, UVB) and crude coal tar (PAHs). Some indicators suggest a genotoxic hazard, however, the level of genotoxic risk of the therapy has not yet been investigated sufficiently.
Andrea Malkova +5 more
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