Scientific Opinion on Flavouring Group Evaluation 57, Revision 1 (FGE.57Rev1): consideration of isopulegone and three flavouring substances evaluated by JECFA (55th meeting) [PDF]
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Anastassiadou, Maria +26 more
core +2 more sources
The genotoxicity of caecal water from gilts following experimentally induced Fusarium mycotoxicosis
The examination of caecal contents allows one to investigate the exposure of colon mucosa to dietary toxins and the chemical contaminants present in animal feed.
A. Nowak +6 more
doaj +1 more source
Evaluation of genotoxicity induced by endodontic materials: A systematic review
The ability of a substance to cause harm to the DNA molecule is known as genotoxicity. Because there is significant evidence of link between genetic damage and carcinogenesis, determining the real health hazards to patients and dental workers requires a ...
Sadaf Tamanna +3 more
doaj +1 more source
Permitted daily exposure for diisopropyl ether as a residual solvent in pharmaceuticals [PDF]
Solvents can be used in the manufacture of medicinal products provided their residual levels in the final product comply with the acceptable limits based on safety data.
Evandri, Maria Grazia, Romanelli, Luca
core +1 more source
Genotoxic and stress inductive potential of cadmium in Xenopus laevis larvae [PDF]
The present investigation evaluates the toxic potential of Cd in larvae of the frog Xenopus laevis after 12 days of exposure to environmentally relevant contamination levels, close to those measured in the river Lot (France).
Baudrimont, Magalie +6 more
core +3 more sources
Safety assessment of the substance phosphorous acid, mixed 2,4-bis(1,1-dimethylpropyl)phenyl and 4-(1,1-dimethylpropyl)phenyl triesters for use in food contact materials [PDF]
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Barthélémy, Eric +24 more
core +2 more sources
The genotoxicity of white phosphorus was previously evaluated using the Ames test, which demonstrated the absence of toxicity. However, with all the advantages of this method, the use of the Ames test has some shortfallsin assessing genotoxicity.
Mindubaev Anton +4 more
doaj +1 more source
Impacts of in vivo and in vitro exposures to tamoxifen: comparative effects on human cells and marine organisms [PDF]
Tamoxifen (TAM) is a first generation-SERM administered for hormone receptor-positive (HER+) breast cancer in both pre- and post-menopausal patients and may undergo metabolic activation in organisms that share similar receptors and thus face comparable ...
Abessa, D. M. S. +5 more
core +1 more source
Toxic and genotoxic potential evaluation of soil samples by bioassays
Soil samples were obtained from Slovenian industrial region Šaleška dolina and aqueous leachates were prepared. The toxicity and genotoxicity potential of these aqueous fractions have been evaluated by in vitro toxicity and genotoxicity bioassays ...
Barbara LAH +3 more
doaj +1 more source
Common Considerations for Genotoxicity Assessment of Nanomaterials
Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or indirect DNA interaction. Testing may be a surrogate for assessment of heritable genetic risk or carcinogenic risk.
Rosalie K. Elespuru +7 more
doaj +1 more source

