The genotoxicity of caecal water from gilts following experimentally induced Fusarium mycotoxicosis
The examination of caecal contents allows one to investigate the exposure of colon mucosa to dietary toxins and the chemical contaminants present in animal feed.
A. Nowak+6 more
doaj +1 more source
Scientific Opinion on Flavouring Group Evaluation 7, Revision 5 (FGE.07Rev5) : saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched‐chain carboxylic acids from chemical group 5 [PDF]
Acknowledgements: The Panel wishes to thank the members of the Working Group on Flavourings: Ulla Beckman Sundh, Leon Brimer, Karl-Heinz Engel, Paul Fowler, Rainer Gürtler, Trine Husøy, Wim Mennes and Gerard Mulder for the preparatory work on this ...
Anastassiadou, Maria+25 more
core +2 more sources
Evaluation of genotoxicity induced by endodontic materials: A systematic review
The ability of a substance to cause harm to the DNA molecule is known as genotoxicity. Because there is significant evidence of link between genetic damage and carcinogenesis, determining the real health hazards to patients and dental workers requires a ...
Sadaf Tamanna+3 more
doaj +1 more source
Permitted daily exposure for diisopropyl ether as a residual solvent in pharmaceuticals [PDF]
Solvents can be used in the manufacture of medicinal products provided their residual levels in the final product comply with the acceptable limits based on safety data.
Evandri, Maria Grazia, Romanelli, Luca
core +1 more source
Turned on by genotoxic stress [PDF]
Comment on: Travesa A, et al. EMBO J 2012; 31:1811-22.
Curt Wittenberg, Anna Travesa
openaire +3 more sources
Impacts of in vivo and in vitro exposures to tamoxifen: comparative effects on human cells and marine organisms [PDF]
Tamoxifen (TAM) is a first generation-SERM administered for hormone receptor-positive (HER+) breast cancer in both pre- and post-menopausal patients and may undergo metabolic activation in organisms that share similar receptors and thus face comparable ...
Abessa, D. M. S.+5 more
core +1 more source
Genotoxic and stress inductive potential of cadmium in Xenopus laevis larvae [PDF]
The present investigation evaluates the toxic potential of Cd in larvae of the frog Xenopus laevis after 12 days of exposure to environmentally relevant contamination levels, close to those measured in the river Lot (France).
Baudrimont, Magalie+6 more
core +3 more sources
Genotoxicity of plant extracts [PDF]
Aqueous extracts of seven species used in Brazilian popular medicine (Achyrocline satureoides, Iodina rhombifolia, Desmodium incanum, Baccharis anomala, Tibouchina asperior, Luehea divaricata, Maytenus ilicifolia) were screened to the presence of mutagenic activity in the Ames test (Salmonella/microsome).
Vargas, Vera M. F.+2 more
openaire +5 more sources
Genotoxicity testing of nanomaterials
AbstractNanomaterials have outstanding and unprecedented advantageous material properties but may also cause adverse effects in humans upon exposure. Testing nanomaterials for genotoxic properties is challenging because traditional testing methods were designed for small, soluble molecules and may not be easily applicable without modifications.
Robert Landsiedel+4 more
openaire +2 more sources
The genotoxicity of white phosphorus was previously evaluated using the Ames test, which demonstrated the absence of toxicity. However, with all the advantages of this method, the use of the Ames test has some shortfallsin assessing genotoxicity.
Mindubaev Anton+4 more
doaj +1 more source