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The Enterobacterial Genotoxins: Cytolethal Distending Toxin and Colibactin
EcoSal Plus, 2016While the DNA damage induced by ionizing radiation and by many chemical compounds and drugs is well characterized, the genotoxic insults inflicted by bacteria are only scarcely documented. However, accumulating evidence indicates that we are exposed to bacterial genotoxins.
Taieb, Frederic +3 more
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Schistosome related cancers: A possible role for genotoxins
Environmental Mutagenesis, 1985AbstractSchistosomiasis has long been associated with cancer. This association is most prevalent between Schistosoma hematobium and bladder cancer. Numerous theories have been proposed to explain the causal link between the parasite infestation and the ensuing neoplasia. One theory that has not received as much attention as others, however, is the role
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Genotoxin-Induced Apoptosis: Implications for Carcinogenesis
1994Apoptosis is thought to be a programmed form of cell death which, when balanced by cell proliferation, contributes to the regulation of tissue homeostasis (1). An imbalance between apoptosis and proliferation may be a factor in tumorigenesis. Apoptosis differs from necrosis both morphologically and biochemically. Necrotic cells exhibit an early loss of
Steven R. Patierno +5 more
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Colibactin: understanding an elusive gut bacterial genotoxin
Natural Product Reports, 2015This highlight reviews recent studies of colibactin, a structurally uncharacterized genotoxin synthesized by members of the human gut microbiota.
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Thresholds for genotoxins and their application in risk assessment
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2009Carmichael, Paul +2 more
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Current Knowledge of Mechanisms of Carcinogenicity: Genotoxins versus Non-genotoxins
Human & Experimental Toxicology, 1994openaire +2 more sources
Genotoxin-responsive DNA capsules for the detection of styrene oxide
Sensors and Actuators B: Chemical, 2021Min-Chieh Chuang, Wei-Ching Liao
exaly