Results 121 to 130 of about 58,106,402 (334)
Utilization of Genotyping-by-Sequencing (GBS) for Rice Pre-Breeding and Improvement: A Review
, 2022 Molecular markers play a crucial role in the improvement of rice. To benefit from these markers, genotyping is carried out to identify the differences at a specific position in the genome of individuals.
Doi, Kazuyuki +9 more
core +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
, 2019 Next Generation Sequencing (NGS) and related technologies have revolutionized the field of conservation and population genetics, providing novel tools and the capacity to discover thousands of new Single Nucleotide Polymorphisms (SNPs) for the analysis ...
Pezaro, Nadav +27 more
core +2 more sources
, 2016 The poster summarizes a collaborative project between the University of Tennessee and the University of Georgia. Genotyping-by-sequencing analysis was performed to determine the genetic variation among ultradwarf bermudagrass cultivars and off-type ...
Meg Staton (654692) +6 more
core +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Genotyping-by-Sequencing application in Chinook Salmon
, 2016 Genomics and DNA sequencing technologies are rapidly advancing to the point where they can be cost effectively applied within aquaculture breeding programmes.
Hayley Baird (8845760) +5 more
core
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Analysis methods for low-depth genotyping-by-sequencing data
, 2020 Outline -- Genotyping-By-Sequencing -- QC / filtering -- Relatedness & Parentage -- Allele sampling models -- Population Genetics -- Hardy-Weinberg -- FST -- Student’s ...
Ken Dodds (3501542)
core
Genomic Selection in Wheat Breeding using Genotyping‐by‐Sequencing
The Plant Genome, 2012 Genomic selection (GS) uses genomewide molecular markers to predict breeding values and make selections of individuals or breeding lines prior to phenotyping. Here we show that genotyping‐by‐sequencing (GBS) can be used for de novo genotyping of breeding panels and to develop accurate GS models, even for the large, complex, and ...
Poland, Jesse A. +10 more
openaire +3 more sources
FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source