Results 81 to 90 of about 10,219,641 (384)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Individual Identification of Cartilage by Direct Amplification in Mass Disasters [PDF]

Fayixue Zazhi, 2017
Objective To explore the effectiveness of direct amplification for the STR analysis of cartilage, and to accelerate the effectiveness of disaster victim identification.
WANG CHUAN-HAI, XU CHENG, LI XIANG-QIN, ET AL.
doaj   +1 more source

High throughput SNP discovery and genotyping in hexaploid wheat

PLoS ONE, 2018
Because of their abundance and their amenability to high-throughput genotyping techniques, Single Nucleotide Polymorphisms (SNPs) are powerful tools for efficient genetics and genomics studies, including characterization of genetic resources, genome-wide
Hélène Rimbert, Benoît Darrier, Julien Navarro, Jonathan Kitt, F. Choulet, M. Leveugle, Jorge Duarte, N. Rivière, K. Eversole, J. Le Gouis, Alessandro Davassi, F. Balfourier, M. Le Paslier, A. Bérard, D. Brunel, C. Feuillet, C. Poncet, P. Sourdille, E. Paux   +18 more
semanticscholar   +1 more source

Reliable microsatellite genotyping of the Eurasian badger (Meles meles) using faecal DNA [PDF]

, 2003
The potential link between badgers and bovine tuberculosis has made it vital to develop accurate techniques to census badgers. Here we investigate the potential of using genetic profiles obtained from faecal DNA as a basis for population size ...
Boom R, Bruford MW, Christian SF, Dytham C, Evett IW, Jansman HAH, Krebs JR, Miller CR, Murphy MA, Neal E, Otis DL, Sambrook J, Seymour SB, Valière N, Walsh PA, Woods JG   +15 more
core   +2 more sources

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Six novel O genotypes from Shiga toxin-producing Escherichia coli

Frontiers in Microbiology, 2016
Serotyping is one of the typing techniques used to classify strains within the same species. O-serogroup diversification shows a strong association with the genetic diversity of O-antigen biosynthesis genes.
Atsushi eIguchi, Sunao eIyoda, Kazuko eSeto, Hironobu eNishii, Makoto eOhnishi, Hirohisa eMekata, Hirohisa eMekata, Yoshitoshi eOgura, Tetsuya eHayashi   +8 more
doaj   +1 more source

Molecular Epidemiology of Aspergillus fumigatus in Chronic Pulmonary Aspergillosis Patients

Journal of Fungi, 2021
Molecular fungal genotyping techniques developed and employed for epidemiological studies have understandably concentrated on establishing the genetic diversity of Aspergillus fumigatus in invasive aspergillosis due to its severity, the urgency for ...
Mireille H. van der Torre, Hongwei Shen, Riina Rautemaa-Richardson, Malcolm D. Richardson, Lilyann Novak-Frazer   +4 more
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Comparative analysis of minor histocompatibility antigens genotyping methods

Онкогематология, 2016
The wide range of techniques could be employed to find mismatches in minor histocompatibility antigens between transplant recipients and their donors. In the current study we compared three genotyping methods based on polymerase chain reaction (PCR) for ...
A. S. Vdovin, A. M. Postovskaya, N. A. Bykova, D. S. Romaniuk, A. K. Alieva, P. R. Yefimova, S. A. Sheetikov, H. L. Julhakyan, G. A. Efimov   +8 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source