Results 31 to 40 of about 20,940 (309)

Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009
Background and Objectives: Mixed germ cell tumors of the ovary, uncommon but aggressive tumors are seen most often in young women or adolescent girls, and are generally curable if found and treated early.
Z. Ebrahimi, Z. Khalaji Nia
doaj   +2 more sources

Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. [PDF]

open access: yes, 2015
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the fusion protein PAX3-FKHR or PAX7-FKHR, and embryonic RMS, which is usually ...
Duan, Zhenfeng   +5 more
core   +3 more sources

A Case of Sarcoidosis Disseminated to Skeletal Tissues

open access: yesInternational Journal of Medical Students, 2013
Sarcoidosis is a systemic granulomatous disease of unknown etiology that typically affects young adults. Diagnostic criteria for sarcoidosis include involvement of two or more of the following organ systems: 1) pulmonary infiltrates; 2) bilateral hilar ...
Edon Rabinowitz   +2 more
doaj   +1 more source

Germ Cell Tumor Presenting with Precocious Puberty in a Girl in United Arab Emirates

open access: yesDubai Medical Journal, 2020
We herein report a rare case of malignant mixed germ cell tumor comprising both an embryonal carcinoma (60%) and a yolk sac tumor (40%). A 7-year-old girl presented to the emergency department with persistent vaginal bleeding, abdominal pain, and ...
Asim Noor Rana   +4 more
doaj   +1 more source

Integrated Molecular Characterization of Testicular Germ Cell Tumors

open access: yesCell Reports, 2018
Summary: We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited high aneuploidy and a paucity of somatic mutations.
Hui Shen   +240 more
doaj   +1 more source

Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells [PDF]

open access: yesProceedings of the National Academy of Sciences, 2017
Significance Primordial germ cells (PGCs) are the origin of germ cells and are critically important for continuity of multicellular organisms. Although the unique characteristics of mouse PGCs have been described in gene expression and epigenome levels, the metabolomic and proteomic profiles of PGCs and their significance for PGC properties ...
Yohei Hayashi   +9 more
openaire   +2 more sources

The present and future of serum diagnostic tests for testicular germ cell tumours. [PDF]

open access: yes, 2016
Testicular germ cell tumours (GCTs) are the most common malignancy occurring in young adult men and the incidence of these tumours is increasing. Current research priorities in this field include improving overall survival for patients classified as ...
A Lorch   +72 more
core   +2 more sources

ErbBs inhibition by lapatinib blocks tumor growth in an orthotopic model of human testicular germ cell tumor [PDF]

open access: yes, 2018
In this work, we have analyzed the expression of different members of the ErbB family in human samples of testicular germ cell tumors (GCTs). We observed expression of ErbB1 or ErbB2 in different tumor subtypes, but we also found high expression of ErbB3
Casanovas i Casanovas, Oriol   +13 more
core   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

An unusual cause of gynaecomastia in a male [PDF]

open access: yes, 2019
Summary: Beta-human chorionic gonadotropin (βhCG) is normally produced by syncytiotrophoblasts of the placenta during pregnancy and aids embryo implantation.
Bano, G   +4 more
core   +1 more source

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