Results 31 to 40 of about 24,196 (383)
Porcine Germ Cells Phenotype during Embryonic and Adult Development
Animals, 2023 Primordial germ cells (PGCs) are the precursors of gametes. Due to their importance for the formation and reproduction of an organism, understanding the mechanisms and pathways of PGCs and the differences between males and females is essential. However, there is little research in domestic animals, e.g., swine, regarding the epigenetic and pluripotency
Amanda Soares Jorge +10 more
openaire +3 more sources
Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors [PDF]
, 2016 Type II germ cell tumors arise after puberty from a germ cell that was incorrectly programmed during fetal life. Failure of testicular germ cells to properly differentiate can lead to the formation of germ cell neoplasia in situ of the testis; this ...
Bowles, J. (Josephine) +6 more
core +1 more source
Treatment of clinical stage I non-seminoma
Asian Journal of Urology, 2021 Germ cell cancers are the most common solid tumors among men between 15 and 40 years. Non-seminomatous germ cell tumors (NSGCTs) represent a unique and exclusive cohort of germ cell tumor patients. Non-seminoma can harbor different histologic components.
Christian Winter, Andreas Hiester
doaj +1 more source
To Be or Not to Be a Germ Cell: The Extragonadal Germ Cell Tumor Paradigm
International Journal of Molecular Sciences, 2021 In the human embryo, the genetic program that orchestrates germ cell specification involves the activation of epigenetic and transcriptional mechanisms that make the germline a unique cell population continuously poised between germness and pluripotency.
M. De Felici +5 more
semanticscholar +1 more source
Korean Journal of Radiology, 2021 Metastatic mature teratoma is a common radiologic and histopathologic finding after chemotherapy for metastatic non-seminomatous germ cell tumors. The leading theory for these residual tumors is the selective chemotherapy resistance of teratomas versus ...
Daniel B. Green +4 more
semanticscholar +1 more source
Dysgerminoma with Embryonal Carcinoma, a Rare Ovarian Malignant Mixed Germ Cell Tumor in a 13-Year-Old Girl: A Case Report [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i ĪrānIntroduction: Pediatric patients rarely develop ovarian tumors, but mainly develop ovarian germ cell tumors. Malignant germ cell tumors are generally rare and dysgerminoma is the most frequent malignant ovarian neoplasm in young and adolescent girls.
Mahsa Akbari Oryani +3 more
doaj +1 more source
Oncology Research and Treatment, 2021 Objective: The aim of this study was to investigate the clinicopathological prognostic factors of malignant ovarian germ cell tumors (MOGCT) and evaluate the survival trends of MOGCT by histotype. Methods: We extracted data on 1,963 MOGCT cases diagnosed
Huimin Guo +3 more
semanticscholar +1 more source
Cell Reports, 2017 Summary: Testicular germ cell tumors (TGCTs) are among the most responsive solid cancers to conventional chemotherapy. To elucidate the underlying mechanisms, we developed a mouse TGCT model featuring germ cell-specific Kras activation and Pten ...
Timothy M. Pierpont +15 more
doaj +1 more source
The histologic features of intratubular germ cell neoplasia and its correlation with tumor behavior [PDF]
Investigative and Clinical Urology, 2016 Purpose: To assess the prevalence of intratubular germ cell neoplasia (ITGCN) in patients with concurrent testis tumor and its correlation with histologic features and serum tumor markers.
Abbas Basiri +4 more
doaj +1 more source
Testicular germ cell tumors arise in the absence of sex-specific differentiation.
Development, 2021 In response to signals from the embryonic testis, the germ cell intrinsic factor NANOS2 coordinates a transcriptional program necessary for the differentiation of pluripotent-like primordial germ cells toward a unipotent spermatogonial stem cell fate ...
N. Webster +8 more
semanticscholar +1 more source