Results 71 to 80 of about 21,086 (311)

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Cell Germ primary tumor of mediastinum (seminoma of mediastinum)

Archivo Médico de Camagüey, 2019
Background: the anterior mediastinal germ cell tumor is a formation of neoplastic cells located in the mediastinum. They are formed by congenital defects in the embryonic stage by migration of the primordial germ cell and dermal cells that are within the
René Hernández-Benedicto, Rafael Pila-Pérez, Pedro Rosales-Torres   +2 more
doaj  

Imprinting Status of Gα_S, NESP55, and XLαs in Cell Cultures Derived from Human Embryonic Germ Cells: GNAS Imprinting in Human Embryonic Germ Cells [PDF]

Clinical and Translational Science, 2009
Abstract GNAS is a complex gene that through use of alternative first exons encodes signaling proteins Gαs and XLαs plus neurosecretory protein NESP55. Tissue‐specific expression of these proteins is regulated through reciprocal genomic imprinting in fully differentiated and developed tissue.
Janet L, Crane, Michael J, Shamblott, Joyce, Axelman, Stephanie, Hsu, Michael A, Levine, Emily L, Germain-Lee   +5 more
openaire   +2 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Bilateral Synchronous Testis Tumors of Different Histology: A Case Report

Caspian Journal of Internal Medicine, 2020
Background: Bilateral synchronous testis germ cell tumors with different histopathology are not common. Case Presentation: Here, a case of 27-year-old male who is reported presented with bilateral testicular swellings.
Ghasem Rostami, Hamid Shafi, Mohammad Ranaee, Samaneh Saeedfar, Fatemeh Mahmodloo   +4 more
doaj  

Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours. [PDF]

, 2013
BACKGROUND: The RNase III enzyme DICER1 plays a central role in maturation of microRNAs. Identification of neoplasia-associated germ-line and somatic mutations in DICER1 indicates that mis-expression of miRNAs in cancer may result from defects in their ...
Bahubeshi, Amin, Foulkes, William D, Kanetsky, Peter A, Nathanson, Katherine L, Sabbaghian, Nelly, Shuen, Andrew Y, Tischkowitz, Marc D   +6 more
core   +2 more sources

Serum free culture and characterization of human embryonic germ cells [PDF]

Cell Research, 2008
Many proteins and growth factors in serum play important roles in the propagation of embryonic stem (ES) cells. But there are some disadvantages in using the serum to culture ES cells. We examined the effects of a chemically-defined culture system knock-out serum replacement (KSR) in the absence of FBS on the growth and differentiation of human ...
JinLian Hua, Hai-sheng Yu, Sheng Liu, Zhongying Dou   +3 more
openaire   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Diagnostic value of qualitative and strain ratio elastography in the differential diagnosis of non-palpable testicular lesions [PDF]

, 2016
The purpose of this study was to evaluate prospectively the accuracy of qualitative and strain ratio elastography (SE) in the differential diagnosis of non-palpable testicular lesions.
BARBAGALLO, FEDERICA, CANTISANI, VITO, CRISTINI, Cristiano, DI PIERRO, GIOVANNI BATTISTA, FATTORINI, GIORGIO, FRANCO, Giorgio, GIANFRILLI, DANIELE, GIANNETTA, ELISA, ISIDORI, Andrea, LENZI, Andrea, Nicolai, E., POZZA, CARLOTTA, Sidhu, P. S.   +12 more
core   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source