Results 71 to 80 of about 12,778 (301)

Bilateral Synchronous Testis Tumors of Different Histology: A Case Report

Caspian Journal of Internal Medicine, 2020
Background: Bilateral synchronous testis germ cell tumors with different histopathology are not common. Case Presentation: Here, a case of 27-year-old male who is reported presented with bilateral testicular swellings.
Ghasem Rostami, Hamid Shafi, Mohammad Ranaee, Samaneh Saeedfar, Fatemeh Mahmodloo   +4 more
doaj  

Investigations into the use of human embryonal carcinoma stem cells as a model to study dopaminergic neurogenesis [PDF]

, 2009
Parkinson's disease in reality arises as a result of a complex series of events, however it is strongly linked to the loss of a specific cellular population of midbrain dopaminergic neurons making it a candidate for stem cell based research.
Bramwell, Thomas William
core  

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Cell Germ primary tumor of mediastinum (seminoma of mediastinum)

Archivo Médico de Camagüey, 2019
Background: the anterior mediastinal germ cell tumor is a formation of neoplastic cells located in the mediastinum. They are formed by congenital defects in the embryonic stage by migration of the primordial germ cell and dermal cells that are within the
René Hernández-Benedicto, Rafael Pila-Pérez, Pedro Rosales-Torres   +2 more
doaj  

In vitro derivation of germ cells from embryonic stem cells

Frontiers in Bioscience, 2010
Embryonic stem cells (ESCs) have the potential to differentiate into cells of all tissue types, as demonstrated by their capability to contribute to the development of all germ layers in chimeras and to form teratomas. Of interest, however, is the lack of evidence of gametogenic gonadal tissues within teratomas, such as testicular tubules or follicles.
Kinarm, Ko, Karin, Huebner, Jeanine, Mueller-Keuker, Hans R, Schoeler   +3 more
openaire   +2 more sources

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Embryonic Stem Cells and the Germ Cell Lineage

, 2011
Stem cells possess the unique ability to either propagate by self-renewal or to differentiate to mature tissues under the influence of appropriate molecular cues. This remarkable feature, also termed “stem cell potency” has been the focus of both a historical and current research spotlight on stem cells, and particularly the potential for human stem ...
Cyril Ramathal, Renee Reijo, Paul Turek
openaire   +2 more sources

Primordial Germ Cell Specification from Embryonic Stem Cells

PLoS ONE, 2008
Primordial germ cell (PGC) specification is the first crucial step in germ line development. However, owing to significant challenges regarding the in vivo system, such as the complex cellular environment and potential problems with embryo manipulation, it is desirable to generate embryonic stem (ES) cells that are capable of overcoming these ...
Wei Wei, Tingting Qing, Xin Ye, Haisong Liu, Donghui Zhang, Weifeng Yang, Hongkui Deng   +6 more
openaire   +4 more sources

Non-seminomatous germ cell tumours

, 2014
The group of non-seminomatous germ cell tumors can be morphologically and therapeutically distinguished from the group of seminomas. The group of non-seminomatous germ cell tumors includes embryonal carcinoma, yolk sac tumor, choriocarcinoma and teratoma.
Behnes, Carl Ludwig, Bremmer, Felix, Schweyer, Stefan   +2 more
core   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source