Results 91 to 100 of about 12,778 (301)
Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes
Reproductive Biology and Endocrinology, 2011 Background Estrogen signaling is mediated by estrogen receptor beta isoforms in normal and neoplastic human testes. Recently, a G-protein-coupled-receptor (GPER) has been suggested as being involved in rapid responses to estrogens in different normal and
Maggiolini Marcello +4 more
doaj +1 more source
The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos
Advanced Science, EarlyView.Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan +8 more
wiley +1 more source
The human germ cell lineage: pluripotency, tumourigenesis and proliferation
, 2008 EThOS - Electronic Theses Online ServiceGBUnited ...
Perrett, Rebecca Mary
core
Neoplasia testicular de células germinativas: estudo retrospectivo de 57 casos. [PDF]
, 1997 Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis ...
Merlim, Sérgio Eduardo
core
New anti-cancer strategies in testicular germ cell tumors
, 2019 The most common solid malignancy of young men aged 20 to 34 years is testicular germ cell tumor. In addition, the incidence of these tumors has significantly increased throughout the last years.
Chieffi P., De Martino M., Esposito F.
core +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
GPR30 is overexpressed in post-puberal testicular germ cell tumors
, 2011 GPR30 is a 7-transmembrane G protein-coupled estrogen receptor that functions alongside traditional estrogen receptors to regulate cellular responses to 17β-estradiol and environmental estrogens.
Ferrara D. +10 more
core +2 more sources
Nanotechnology Applied to Stem Cell-Substratum Interactions [PDF]
, 2008 The modulation of biological interaction with artificial surfaces is a vital aspect of biomaterials research. Perhaps the most challenging area is transplantation involving the introduction of stem cells into the body with their ability to ...
Aref, Amirreza
core
Advanced Science, EarlyView.After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source
Erectile Dysfunction in Germ Cell Tumor Survivors
The World Journal of Men's Health, 2021 Purpose: Germ cell tumors (GCTs) are the most common malignant neoplasms in adolescents and young adults, and most patients with these tumors can be completely cured. Therefore, maintaining quality of life (QOL) is important.
Koichi Okada +6 more
doaj +1 more source