Results 81 to 90 of about 181,469 (346)
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
Association of Cystic Medial Necrosis of the Aorta and Undiagnosed Thyroiditis [Scripta Medica] [PDF]
We have recently seen two patients with cystic medial necrosis of the aorta. The first patient died of a dissecting aneurysm of the thoracic aorta. At autopsy, classical Hashimoto’s thyroiditis was discovered.
Hain, John R., Wise, William S.
core +1 more source
Atypical chemokine receptor 4 shapes activated B cell fate [PDF]
Activated B cells can initially differentiate into three functionally distinct fates-early plasmablasts (PBs), germinal center (GC) B cells, or early memory B cells-by mechanisms that remain poorly understood.
Alsharifi, Mohammed+20 more
core +2 more sources
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
A mathematical model for the germinal center morphology and affinity maturation [PDF]
During germinal center reactions the appearance of two specific zones is observed: the dark and the light zone. Up to now, the origin and function of these zones are poorly understood. In the framework of a stochastic and discrete model several possible pathways of zone development during germinal center reactions are investigated.
arxiv
Non-Hausdorff germinal groupoids for actions of countable groups [PDF]
We study conditions under which the germinal groupoid associated to a minimal equicontinuous action of a countable group on a Cantor set has non-Hausdorff topology. We develop a new criterion, which serves as an obstruction for the \'etale topology on the groupoid to be non-Hausdorff.
arxiv
A Probabilistic Model of the Germinal Center Reaction [PDF]
Frontiers in Immunology ...
Marcel Jan Thomas+4 more
openaire +6 more sources
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
SAP (SH2D1A) is required intrinsically in CD4 T cells to generate germinal center responses and long-term humoral immunity. SAP binds to SLAM family receptors, including SLAM, CD84, and Ly108 to enhance cytokine secretion and sustained T cell:B cell ...
Joyce K Hu+3 more
doaj +1 more source
Background Research on prognostically relevant immunohistochemical markers in diffuse large B-cell lymphomas has mostly been performed on retrospectively collected clinical data.
Heinz-Wolfram Bernd+19 more
doaj +1 more source