Results 41 to 50 of about 26,681 (151)
Parasites & VectorsBackground Cystic echinococcosis (CE) and alveolar echinococcosis (AE) are zoonotic diseases caused by the larval stages of Echinococcus granulosus and E. multilocularis.
Leonard Schreiber +6 more
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B cell intrinsic and extrinsic factors impacting memory recall responses to SRBC challenge
Frontiers in Immunology, 2022 MBCs (MBCs) generated in T-dependent immune responses can persist for a lifetime and rapidly react upon secondary antigen exposure to differentiate into plasma cells (PCs) and/or to improve the affinity of their BCR through new rounds of hypermutation in
Viviana Valeri +9 more
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Secretory IgA (SIgA): designed for antimicrobial defence
Frontiers in Immunology, 2013 Prevention of infections by vaccination remains a compelling goal to improve public health. Mucosal vaccines would make immunization procedures easier, be better suited for mass administration, and most efficiently induce immune exclusion -- a term ...
Per eBrandtzaeg
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NGFR regulates stromal cell activation in germinal centers
Cell ReportsSummary: Nerve growth factor receptor (NGFR) is expressed by follicular dendritic cells (FDCs). However, the role of NGFR in the humoral response is not well defined.
Alberto Hernández-Barranco +18 more
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Antigen presentation by B cells enables epitope spreading across an MHC barrier
Nature Communications, 2023 Circumstantial evidence suggests that B cells may instruct T cells to break tolerance. Here, to test this hypothesis, we used a murine model in which a single B cell clone precipitates an autoreactive response resembling systemic lupus erythematosus (SLE)
Cecilia Fahlquist-Hagert +22 more
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Morphological changes in lymph nodes and spleen upon EAE induction in C57BL/6 mic [PDF]
Archives of Biological Sciences, 2013 Myelin oligodendrocyte glycoprotein (MOG) is a protein widely used in the induction of experimental autoimmune encephalomyelitis (EAE) for studying human multiple sclerosis (MS).
Maslovarić Irina +4 more
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Capturing change in clonal composition amongst single mouse germinal centers
eLife, 2018 Understanding cellular processes occurring in vivo on time scales of days to weeks requires repeatedly interrogating the same tissue without perturbing homeostasis.
Daniel J Firl +3 more
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Cell Reports, 2019 Summary: Germinal centers (GC) are crucial for the formation of long-lived humoral immunity. Many pathogens suppress GC, including Salmonella enterica serovar Typhimurium (STm), but the mechanisms driving suppression remain unknown.
Rebecca A. Elsner, Mark J. Shlomchik
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DNA immunisation. New histochemical and morphometric data
European Journal of Histochemistry, 2010 Splenic germinal center reactions were measured during primary response to a plasmidic DNA intramuscular injection. Cardiotoxin-pretreated Balb/c mice were immunized with DNA plasmids encoding or not the SAG1 protein, a membrane antigen of Toxoplasma ...
D Ehirchiou +10 more
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Inference of germinal center evolutionary dynamics via simulation-based deep learning
eLifeB cells and the antibodies they produce are vital to health and survival, motivating research on the details of the mutational and evolutionary processes in the germinal centers (GCs) from which mature B cells arise.
Duncan K Ralph +8 more
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