Results 31 to 40 of about 26,681 (151)
Affinity Selection in Germinal Centers: Cautionary Tales and New Opportunities
Cells, 2021 Our current quantitative knowledge of the kinetics of antibody-mediated immunity is partly based on idealized experiments throughout the last decades.
Jose Faro, Mario Castro
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The Biology of the Germinal Center [PDF]
Hematology, 2007 The immune system requires the production of high affinity antibodies of different subclasses to accomplish its many effector functions. Specific steps in B-cell ontogeny that occur within germinal centers of secondary lymphoid organs create much of the diversity in the immune system.
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Functional zones of Peyer’s patch (PPs) in rabbits’ caecum
Theoretical and Applied Veterinary Medicine, 2021 A feature of rabbit gut-associated lymphoid tissue is that its structure is more developed than in other animal species. In rabbits it is composed of sacculus rotundus, vermiform appendix and Peyer’s patches.
M. O. Nikitina +2 more
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Cytokines in the Germinal Center Niche [PDF]
Antibodies, 2016 Cytokines are small, secreted, glycoproteins that specifically affect the interactions and communications between cells. Cytokines are produced transiently and locally, acting in a paracrine or autocrine manner, and they are extremely potent, ligating high affinity cell surface receptors to elicit changes in gene expression and protein synthesis in the
Jandl, C, King, C
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Regulation of the Germinal Center Response [PDF]
Frontiers in Immunology, 2018 The germinal center (GC) is a specialized microstructure that forms in secondary lymphoid tissues, producing long-lived antibody secreting plasma cells and memory B cells, which can provide protection against reinfection. Within the GC, B cells undergo somatic mutation of the genes encoding their B cell receptors which, following successful selection ...
Marisa Stebegg +8 more
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Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers. [PDF]
PLoS ONE, 2013 Lymphoid tissue immunopathology is a characteristic feature of chronic HIV/SIV infection in AIDS-susceptible species, but is absent in SIV-infected natural hosts.
Amanda J Martinot +9 more
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Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells
Viruses, 2022 Tissue and subcellular localization and its changes upon cell activation of virus-restricting APOBEC3 at protein levels are important to understanding physiological functions of this cytidine deaminase, but have not been thoroughly analyzed in vivo.
Shota Tsukimoto +8 more
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Nodular Lymphocyte-Predominant Hodgkin Lymphoma in Progressive Transformation of Germinal Centers
Case Reports in Otolaryngology, 2017 Nodular lymphocyte-predominant Hodgkin lymphoma is an uncommon variant of Hodgkin lymphoma. Progressive transformation of germinal centers has been associated with and can develop prior to, concurrent with, or after the diagnosis of nodular lymphocyte ...
C. Eric Bailey +4 more
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Twin Rectal Tonsils Mimicking Carcinoid or Mucosa-Associated Lymphoid Tissue Lymphoma [PDF]
Clinical Endoscopy, 2017 The rectal tonsil is a rare polypoid lesion exclusively found in the rectum and is considered a reactive proliferation of the lymphoid tissue. Although this lesion is benign, we recommend that it should be differentiated from carcinoid or polypoid type ...
Masanori Takehara +7 more
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Germinal Center Optimization Algorithm [PDF]
International Journal of Computational Intelligence Systems, 2018 Artificial immune systems are metaheuristic algorithms that mimic the adaptive capabilities of the immune system of vertebrates. Since the 1990s, they have become one of the main branches of computer intelligence. However, there are still many competitive processes in the biological phenomena that can bring new advances for many applications.
Carlos Villaseñor +4 more
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