Results 41 to 50 of about 194,651 (386)
Marcio Carneiro Vieira,1,2 Fernanda Bezerra de Mello Monte,3 Bruno Eduardo Dematte,3 Tadeu Lima Montagnoli,3 Guilherme Carneiro Montes,3 Jaqueline Soares da Silva,3 Rosalia Mendez-Otero,4 Margarete Manhães Trachez,3 Roberto Takashi Sudo,1,3 Gisele
Vieira M C +9 more
doaj
Properties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice [PDF]
Alexander disease is a fatal leukoencephalopathy caused by dominantly-acting coding mutations in GFAP. Previous work has also implicated elevations in absolute levels of GFAP as central to the pathogenesis of the disease. However, identification of the critical astrocyte functions that are compromised by mis-expression of GFAP has not yet been possible.
Woosung, Cho, Albee, Messing
openaire +2 more sources
Background: The occurrence of ischemia causes a loss of energy to switch to anaerobic processes resulting in acidosis due to reduced Adenosina Triphosphate (ATP). This condition makes neuron cells apoptotic. Apoptotic of several biochemical substrates in
Diah Retno Wahyuningrum +2 more
doaj +1 more source
Increased GFAP concentrations in the cerebrospinal fluid of patients with unipolar depression
Inflammatory processes involving altered microglial activity may play a relevant role in the pathophysiology of depressive disorders. Glial fibrillary acidic protein (GFAP) and calcium-binding protein S100B are considered microglial markers.
Maike Michel +13 more
semanticscholar +1 more source
One of the most remarkable characteristics of astrocytes is their vigorous response to diverse neurologic insults, a feature that is well conserved across a variety of different species. The astroglial response occurs rapidly and can be detected within one hour of a focal mechanical trauma (Mucke et al., 1991).
L F, Eng, R S, Ghirnikar
openaire +2 more sources
Objective: the aim of our work is to describe a condition of the reactive astrocytes in the white matter in preterm and term infants with infectious diseases.Materials and methods: postmortem investigation of periventricular white matter performed on ...
S. V. Barashkova
doaj +1 more source
Increased astrocyte representation in the hippocampus of 5xFAD mice [PDF]
Introduction: Alzheimer's disease is the most common neurodegenerative disorder, characterized by the formation of amyloid plaques and the neurofibrillary tangles in the brain of an ill person, leading to neuronal damage and loss.
Jovanović Violeta +5 more
doaj +1 more source
Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific [PDF]
Despite different aetiologies, most inherited retinal disorders culminate in photoreceptor loss, which induces concomitant changes in the neural retina, one of the most striking being reactive gliosis by Müller cells.
Ali, RR +6 more
core +1 more source
Microstructure white matter changes and serum GFAP among different phenotypes of multiple sclerosis [PDF]
Background. Multiple sclerosis (MS) is an autoimmune disease that targets the central nervous system (CNS). A patient’s degree of demyelination and axonal degeneration can only be roughly estimated based on clinical symptoms, neurochemical analysis or ...
Elsayed Orief +3 more
doaj +1 more source
Role of Aldynoglia Cells in Neuroinflammatory and Neuroimmune Responses after Spinal Cord Injury
Aldynoglia are growth-promoting cells with a morphology similar to radial glia and share properties and markers with astrocytes and Schwann cells. They are distributed in several locations throughout the adult central nervous system, where the cells of ...
Vinnitsa Buzoianu-Anguiano +2 more
doaj +1 more source

