Results 51 to 60 of about 194,651 (386)

Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS. [PDF]

, 2018
Reactive astrocytes influence post-injury recovery, repair, and pathogenesis of the mammalian CNS. Much of the regulation of astrocyte reactivity, however, remains to be understood.
Carolino, Krislyn I, Chen, Meifan, Elzière, Lucie, Geoffroy, Cédric G, Goldberg, Mark P, Jin, Yishi, Khai, Vung S, Kong, Xiangmei, Li, Yunbo, Meves, Jessica M, Narang, Aarti, Nguyen, Mallorie T, Steinke, Christopher L, Zheng, Binhai   +13 more
core   +2 more sources

Serological biomarkers in autoimmune GFAP astrocytopathy

Frontiers in Immunology, 2022
Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a newly defined meningoencephalomyelitis. The pathogenesis of GFAP-A is not well understood. The present study measured the expression levels of 200 serological cytokines in GFAP-A patients, NMOSD patients and healthy controls (HCs). The correlations between serum cytokine levels and
Cong-Cong Fu, Cong-Cong Fu, Lu Huang, Lu Huang, Lu-Fen Xu, Lu-Fen Xu, Li-Hong Jiang, Li-Hong Jiang, Hui-Lu Li, Hui-Lu Li, Sha Liao, Sha Liao, Jiajia Yue, Jiajia Yue, Chun Lian, Chun Lian, Xin-Guang Yang, Xin-Guang Yang, Xin-Guang Yang, You-Ming Long, You-Ming Long   +20 more
openaire   +3 more sources

Chronic chlorinated benzene exposure induces glial cytoskeleton disturbance in the mouse brain and enteric glia

Theoretical and Applied Veterinary Medicine, 2023
Chlorinated benzenesare widely used solvent for various targets including industrial production of adhesives, drugs, rubber, paints and dry cleaning, and as well as fiber-swelling agent in the textile processing.
K. I. Timchyi, D. M. Masiuk, H. V. Sukharenko, V. S. Nedzvetsky   +3 more
doaj   +1 more source

Abnormal motoneuron migration, differentiation, and axon outgrowth in spinal muscular atrophy [PDF]

, 2008
The role of heterotopic (migratory) motoneurons (HMN) in the pathogenesis of spinal muscular atrophy (SMA) is still controversial. We examined the occurrence and amount of HMN in spinal cord tissue from eight children with SMA (six with SMA-I and two ...
Barišić, Nina, Hof, Patrick R., Islam, Atiqul, Jovanov Milošević, Nataša, Krušlin, Božo, Lucassen, Paul J., Mladinov, Mihovil, Pajtak, Alen, Sertić, Jadranka, Šešo Šimić, Đurđica, Šimić, Goran   +10 more
core   +1 more source

GFAP positivity in neurons following traumatic brain injuries

Zeitschrift für Rechtsmedizin, 2021
Glial fibrillary acidic protein (GFAP) is a well-established astrocytic biomarker for the diagnosis, monitoring and outcome prediction of traumatic brain injury (TBI). Few studies stated an accumulation of neuronal GFAP that was observed in various brain
J. Zwirner, J. Lier, H. Franke, N. Hammer, J. Matschke, Florian Trautz, Rexon Tse, B. Ondruschka   +7 more
semanticscholar   +1 more source

Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study [PDF]

, 2019
Microglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative diseases Alzheimer’s disease (AD ...
Benzinger, Tammie L. S., Han, Fei, Morris, John C., Perlmutter, Joel S., Perrin, Richard J., Wang, Qing, Wang, Yong, Xu, Jinbin   +7 more
core   +2 more sources

Cytoarchitectonic features of the neocortex, archicortex and amygdala of white rats after a 20-minute occlusion of the common carotid arteries

Бюллетень сибирской медицины, 2020
Purpose. The study is focused on glioarchitectonics of the neocortex, archicortex and amygdala of Wistar white rats in normal state and after a 20-minute occlusion of the common carotid arteries.Materials and methods.
V. A. Akulinin, D. B. Avdeev, A. S. Stepanov, A. V. Gorbunova, S. S. Stepanov, I. G. Tsuskman   +5 more
doaj   +1 more source

Serum GFAP in multiple sclerosis: correlation with disease type and MRI markers of disease severity

Scientific Reports, 2020
Neurofilament light chain (NfL) has been demonstrated to correlate with multiple sclerosis disease severity as well as treatment response. Nevertheless, additional serum biomarkers are still needed to better differentiate disease activity from disease ...
X. Ayrignac, E. Le Bars, C. Duflos, C. Hirtz, Aleksandra Maleska Maceski, C. Carra-Dallière, M. Charif, F. Pinna, P. Prin, N. Menjot de Champfleur, J. Deverdun, T. Kober, B. Maréchal, M. J. Fartaria, Ricardo A. Corredor Jerez, P. Labauge, S. Lehmann   +16 more
semanticscholar   +1 more source

Antisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment

Science Translational Medicine, 2021
Description Gfap-antisense prevents disease with early treatment and reverses clinical phenotypes with late treatment in a rat model of Alexander disease.
Tracy L. Hagemann, Berit E. Powers, Ni-Hsuan Lin, A. Mohamed, Katerina L Dague, Seth C. Hannah, Gemma Bachmann, C. Mazur, F. Rigo, Abby L. Olsen, M. Feany, M. Perng, R. Berman, A. Messing   +13 more
semanticscholar   +1 more source

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. [PDF]

, 2015
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable.
Cork, SC, Gribble, FM, Holt, MK, Reimann, F, Richards, JE, Trapp, S   +5 more
core   +2 more sources