Results 71 to 80 of about 194,651 (386)

Peripheral GFAP and NfL as early biomarkers for dementia: longitudinal insights from the UK Biobank

BMC Medicine
Background Peripheral glial fibrillary acidic protein (GFAP) and neurofilament light chain (NfL) are sensitive markers of neuroinflammation and neuronal damage.
Xiaofei Wang, Ziyan Shi, Y. Qiu, Dongren Sun, Hongyu Zhou   +4 more
semanticscholar   +1 more source

Serum Glial Fibrillary Acidic Protein (GFAP) Is a Marker of Disease Severity in Frontotemporal Lobar Degeneration

Journal of Alzheimer's Disease, 2020
Background: It is still unknown if serum glial fibrillary acidic protein (GFAP) is a useful marker in frontotemporal lobar degeneration (FTLD). Objective: To assess the diagnostic and prognostic value of serum GFAP in a large cohort of patients with FTLD.
A. Benussi, N. Ashton, T. Karikari, S. Gazzina, E. Premi, L. Benussi, R. Ghidoni, Juan Lantero Rodriguez, A. Emeršič, G. Binetti, Silvia Fostinelli, Marcello Giunta, R. Gasparotti, H. Zetterberg, K. Blennow, B. Borroni   +15 more
semanticscholar   +1 more source

Immunohistochemical detection of axonal injury in chimpanzee (Pan troglodytes) with traumatic and fatal brain injury

Macedonian Veterinary Review
Estimating the time of death after traumatic brain injury (TBI) in wildlife is a significant challenge in forensic veterinary medicine. The understanding of histopathological changes and predicting the survival time can prompt critical emergency measures
Peyman Mohammadzadeh, Ahmad Reza Baharvand, Sajjad Mohammadi, Ramin Fooladi, Kimia Azimi, Erfan Eftekhar   +5 more
doaj   +1 more source

The influence of acelysin and nimotop on the cellular response of the hippocampus during the dynamics of experimental subarachnoid hemorrhage

Patologìâ, 2023
Aim. Immunohistochemical study of rat hippocampal neurons and astrocytes at different time-points of experimental brain hemorrhage treated with acelysin and nimotop. Materials and methods. Subarachnoid hemorrhage (SAH) was modeled according to R.
O. Yu. Polkovnikov, S. I. Tertyshnyi
doaj   +1 more source

Protein kinase a distribution differentiates human glioblastoma from brain tissue [PDF]

, 2017
Brain tumor glioblastoma has no clear molecular signature and there is no effective therapy. In rodents, the intracellular distribution of the cyclic AMP (cAMP)-dependent protein kinase (Protein kinase A, PKA) R2Alpha subunit was previously shown to ...
Caretta, Antonio, D\u2019Avella, Domenico, Denaro, Luca, Mucignat-Caretta, Carla   +3 more
core   +2 more sources

Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles

Brain : a journal of neurology
Glial fibrillary acidic protein (GFAP), a proxy of astrocyte reactivity, has been proposed as biomarker of Alzheimer’s disease. However, there is limited information about the correlation between blood biomarkers and post-mortem neuropathology.
P. Sánchez-Juan, E. Valeriano‐Lorenzo, Alicia Ruiz-Gónzalez, A. Pastor, Héctor Rodrigo Lara, F. López-González, M. Zea-Sevilla, M. Valentí, Belén Frades, Paloma Ruiz, Laura Saiz, Iván Burgueño-García, M. Calero, T. del Ser, A. Rábano   +14 more
semanticscholar   +1 more source

Serum GFAP and UCH-L1 for prediction of absence of intracranial injuries on head CT (ALERT-TBI): a multicentre observational study.

Lancet Neurology, 2018
BACKGROUND More than 50 million people worldwide sustain a traumatic brain injury (TBI) annually. Detection of intracranial injuries relies on head CT, which is overused and resource intensive.
J. Bazarian, P. Biberthaler, R. Welch, L. Lewis, P. Barzó, V. Bogner-Flatz, Gunnar Brolinson, A. Büki, James Chen, R. Christenson, D. Hack, Stephen J. Huff, Sandeep Johar, J. D. Jordan, B. A. Leidel, T. Lindner, E. Ludington, D. Okonkwo, J. Ornato, F. Peacock, Kara S. Schmidt, J. Tyndall, A. Vossough, A. Jagoda   +23 more
semanticscholar   +1 more source

Serum GFAP levels in optic neuropathies [PDF]

Journal of the Neurological Sciences, 2012
Complement mediated autoimmunity against aquaporin-4 results in astrocytic damage in neuromyelitis optica (NMO). There is evidence for increased CSF glial fibrillary acidic protein (GFAP) and S100B levels in acute NMO. Here we tested whether the CSF finding also holds true for the diagnostic value of serum GFAP and S100B levels in NMO.A multicentre ...
Storoni, M., Verbeek, M.M., Verbeek, M.M., Illes, Z., Marignier, R., Teunissen, C.E., Grabowska, M., Confavreux, C., Plant, G.T., Petzold, A.   +9 more
openaire   +5 more sources

Ectomesenchymal chondromyxoid tumor: A rare case report

Annals of Medical Science and Research
Ectomesenchymal chondromyxoid tumor is a very rare tumor, which mostly occurs in the tongue. Here, we are presenting a case of a 55-year-old man with a swelling in the anterior dorsum of his tongue.
Anindita Mondal, Ayesha Afreen Islam, Keya Basu, Uttara Chatterjee   +3 more
doaj   +1 more source

Combining H-FABP and GFAP increases the capacity to differentiate between CT-positive and CT-negative patients with mild traumatic brain injury [PDF]

, 2018
Mild traumatic brain injury (mTBI) patients may have trauma-induced brain lesions detectable using CT scans. However, most patients will be CT-negative. There is thus a need for an additional tool to detect patients at risk. Single blood biomarkers, such
Bustamante, Alejandro, Egea Guerrero, Juan José, El Rahal, Amir, García-Armengol, Roser, Lagerstedt, Linnéa, Melinda Prica, Carmen, Montaner, Joan, Quintana-Díaz, Manuel, Rodríguez Rodríguez, Ana   +8 more
core   +1 more source