Results 181 to 190 of about 4,652 (199)

GGDEF-EAL domain proteins in bacterial physiology

2008
GGDEF and EAL domain proteins were identified in the chromosome of many bacteria. GGDEF domain proteins are generally diguanyl cyclases which synthesize the secondary messenger cyclic di-GMP. EAL domain proteins are generally c-di-GMP specific phosphodiesterase which degrade c-di-GMP.
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GepA, a GGDEF-EAL protein, regulates biofilm formation and swimming motility in Vibrio parahaemolyticus

Archives of Microbiology
Cyclic diguanylate monophosphate (c-di-GMP) is a second messenger that regulates multiple bacterial behaviors. It is synthesized by diguanylate cyclase (DGC) with the GGDEF domain, and degraded by phosphodiesterase (PDE) with the EAL or HD-GYP domain. The GepA (VP0117) protein in Vibrio parahaemolyticus contains both GGDEF and EAL domains, but its role
Miaomiao, Zhang, Yurui, Zhu, Xue, Li, Xi, Luo, Hui, Sun, Shuhui, Xiong, Renfei, Lu, Yiquan, Zhang   +7 more
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[Proteins with GGDEF and EAL domains: their role in bacterial metabolism].

Revista latinoamericana de microbiologia, 2007
The availability of multiple bacterial genome sequences has led to the discovery of several conserved domains of proteins. Recently, GGDEF and EAL domains have been described as domains responsible for the synthesis and degradation of c-di-GMP, a second messenger in bacteria. c-di-GMP has been involved in cellulose production and identified as a global
Micaela Marcela, Méndez-Ortiz, Jorge, Membrillo-Hernández   +1 more
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Cyclic di-GMP Signaling Gone Astray: Cyclic GAMP Signaling via Hypr GGDEF and HD-GYP Enzymes

2020
GGDEF domain and HD-GYP enzymes are classically associated with cyclic di-GMP signaling. Here we describe our current knowledge of variants of these enzyme classes that instead are involved in cyclic GMP-AMP (cGAMP) signaling, including their discovery, recent elucidation of signature active site residues, specific phenotypes, and regulatory mechanisms.
Todd A. Wright, Andrew B. Dippel, Ming C. Hammond   +2 more
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Transcriptional analysis and functional characterization of XCC1294 gene encoding a GGDEF domain protein in Xanthomonas campestris pv. campestris

Archives of Microbiology, 2011
The nucleotide cyclic di-GMP is a second messenger in bacteria that regulates a range of cellular functions including the virulence of pathogens. GGDEF is a protein domain involved in the synthesis of cyclic di-GMP. The genome of the crucifer pathogen Xanthomonas campestris pv. campestris (Xcc) encodes 21 proteins with a GGDEF domain. Clp, a homolog of
Yi-Min, Hsiao, Wan-Ling, Song, Chao-Tsai, Liao, I-Hsuan, Lin, Mei-Ying, Pan, Ching-Fen, Lin   +5 more
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[Expression, purification and activity analysis of GGDEF and EAL domain-containing proteins from Lactobacillus acidophilus].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018
To identify the functions of the proteins containing the GGDEF or EAL domain in Lactobacillus acidophilus for investigation of the regulatory mechanism of c-di-GMP in this strain.The DNA fragments of NH13_07045-GGDEF, NH13_07050 and NH13_07055 from Lactobacillus acidophilus ATCC4356 were amplified by PCR and cloned into the expression vector pMAL-His ...
Jia-Hui, He, Jie-Li, Sun, Wen-Juan, Yan, Fang, Wang   +3 more
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Rapid Detection of Aeromonas veronii Using GGDEF Gene‐Based Colorimetric Loop‐Mediated Isothermal Amplification

Journal of Fish Diseases
ABSTRACTAeromonas veronii has emerged as an important fish pathogen that poses threats to the aquaculture industry worldwide, and rapid detection is essential to minimise negative economic impact. In this study, a colorimetric loop‐mediated isothermal amplification (LAMP) assay was developed to rapidly detect A. veronii, targeting a gene encoding GGDEF
Tien Tien Vicky Lau, Suat Moi Puah, Kek Heng Chua   +2 more
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Identification of Three New GGDEF and EAL Domain-Containing Proteins Participating in the Scr Surface Colonization Regulatory Network in Vibrio parahaemolyticus

Journal of Bacteriology, 2021
Linda L Mccarter
exaly  

Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa

Journal of Bacteriology, 2018
Chong Wai Liew, Yee Hwa Wong, Scott A Rice   +2 more
exaly  

Structural and mechanistic determinants of c-di-GMP signalling

Nature Reviews Microbiology, 2009
Tilman Schirmer, Urs Jenal
exaly