Results 11 to 20 of about 17,618 (160)
GHR/HindIII Locus Polymorphisms in Intron-2 GHR Gene of Papua Local Chicken
Jurnal Sain Peternakan Indonesia, 2021 This study aimed to detect single nucleotide polymorphisms (SNPs) in intron-2 on growth hormone receptor (GHR) gene in Papua local chickens using the PCR-RFLP method to study its relationship with growth characteristics. Data on the bodyweight of 49 chickens aged 1, 2, 3, and 4 months (22 males, 27 females) and DNA samples were used for this study. The
M. A. Mu'in, A. G. Murwanto
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Significant down-regulation of growth hormone receptor expression revealed as a new unfavorable prognos- tic factor in hepatitis C virus-related hepatocellular carcinoma [PDF]
Clinical and Molecular Hepatology, 2021 Background/Aims Growth hormone (GH) is the main regulator of somatic growth, metabolism, and gender dimorphism in the liver. GH receptor (GHR) signaling in cancer is derived from a large body of evidence, although the GHR signaling pathway involved in ...
Ching-Chih Lin +9 more
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Tissue-Specific GHR Knockout Mice: Metabolic Phenotypes [PDF]
Frontiers in Endocrinology, 2015 In addition to its major role in the regulation of somatic growth, growth hormone (GH) signaling has profound effects on function of various tissues in the body. However, the cellular location where the GH signaling exerts its effect on metabolic homeostasis remains largely unknown. Here, we briefly review recent progress and insights from mice with GH
Sun, Liou Y., Bartke, Andrzej
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BMC Psychiatry, 2023 Background Schizophrenia (SZ) arises from a complex interplay involving genetic and molecular factors. Early intervention of SZ hinges upon understanding its vulnerability and resiliency factors in study of SZ and genetic high risk for SZ (GHR).
Jia Duan +10 more
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Heliyon, 2023 Introduction: Several parts of Garcinia hanburyi are used in traditional medicine for many purposes. In this study, Garcinia hanburyi resin (GHR) was explored for possible anti-proliferative effects and the underlying mechanism on colorectal cancer (CRC)
Kanokkorn Vichitsakul +5 more
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Czech Journal of Animal Science, 2018 The association between several gene polymorphisms, the estimated breeding values for milk performance traits, and glucose metabolism measured by the glucose tolerance test (GTT) in German Holstein sires were evaluated.
Jindřich Čítek +5 more
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Frontiers in Plant Science, 2021 Plant lignin is a component of the cell wall, and plays important roles in the transport potential of water and mineral nutrition and plant defence against biotic stresses.
Taiping Wei +11 more
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Sugammadex affects GH/GHR’s signaling transduction on muscle cells by regulating the membrane-localized GHR level [PDF]
Turkish Journal of Biochemistry, 2022 Abstract Objectives Sugammadex (also known as bridion) is a modified γ-cyclodextrin, which is a reversal agent for the neuromuscular block. Growth hormone (GH) has an important biological effect on muscle, regulating muscle growth and development.
Xiaoqian Lyu +3 more
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Cell Communication and Signaling, 2023 Background Myoblast differentiation requires metabolic reprogramming driven by increased mitochondrial biogenesis and oxidative phosphorylation. The canonical GH-GHR-IGFs axis in liver exhibits a great complexity in response to somatic growth.
Bowen Hu +9 more
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Biomolecules, 2023 Laron syndrome (LS) is a rare genetic disorder characterized by low levels of insulin-like growth factor 1 (IGF1) and high levels of growth hormone (GH) due to mutations in the growth hormone receptor gene (GHR). A GHR-knockout (GHR-KO) pig was developed
Marie-Christin Schilloks +6 more
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