Results 31 to 40 of about 22,382 (200)
Molecular Metabolism, 2018 Objective: Laron syndrome (LS) is a rare, autosomal recessive disorder in humans caused by loss-of-function mutations of the growth hormone receptor (GHR) gene.
Arne Hinrichs +18 more
doaj +1 more source
ChickenGHRnatural antisense transcript regulatesGHRmRNA in LMH cells
Oncotarget, 2016 Growth hormone receptor (GHR) played key roles in human and animal growth. Both human laron type dwarfism and sex linked dwarf chicken were caused by the mutation of GHR gene. In this study, we identified an endogenously expressed long non-coding natural antisense transcript, GHR-AS, which overlapped with the GHR mRNA (GHR-S) in a tail to tail manner ...
Zhang, Li +11 more
openaire +3 more sources
SINE Insertion in the Intron of Pig GHR May Decrease Its Expression by Acting as a Repressor
Animals, 2021 The genetic diversity of the GH/IGF axis genes and their association with the variation of gene expression and phenotypic traits, principally represented by SNPs, have been extensively reported.
Cai Chen +8 more
doaj +1 more source
, 2013 (A) HEK293T cells were transfected with Elongin B/C and Myc-GHR and either an Empty vector, FLAG-SOCS2 or a SOCS2 mutant version. C denotes the control which was tranfected with FLAG-SOCS2 and Elongin B/C but not GHR.
Michael Lund Nielsen (172389) +6 more
core +1 more source
Autocrine/paracrine actions of growth hormone in human melanoma cell lines
Biochemistry and Biophysics Reports, 2020 Melanoma is the most aggressive skin cancer. Its aggressiveness is most commonly attributed to ERK pathway mutations leading to constitutive signaling.
Ashiya Buckels +6 more
doaj +1 more source
F1000Research, 2014 The correlation of physiological sensitivity to insulin (vis-à-vis glycemic regulation) and longevity is extensively established, creating a justifiable gerontological interest on whether insulin sensitivity is causative, or even predictive, of some or ...
Oge Arum +6 more
doaj +1 more source
Expression of growth hormone receptor (GHR) in experimental autoimmune encephalomyelitis
, 2019 Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by inflammation, demyelination, neurodegeneration and gliosis.
Božić, Iva +8 more
core +5 more sources
, 2013 Nexus file containing phased alleles from GHR sequences of Javan Crocidura.
Jacob A. Esselstyn (214666) +4 more
core +2 more sources
Opposing Roles of Leptin and Ghrelin in the Equine Corpus Luteum Regulation: An In Vitro Study
Mediators of Inflammation, 2014 Metabolic hormones have been associated with reproductive function modulation. Thus, the aim of this study was: (i) to characterize the immunolocalization, mRNA and protein levels of leptin (LEP), Ghrelin (GHR) and respective receptors LEPR and Ghr-R1A ...
António Galvão +8 more
doaj +1 more source