Results 111 to 120 of about 83,620 (273)

Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg   +3 more
wiley   +1 more source

In1-ghrelin splicing variant is associated with reduced disease-free survival of breast cancer patients and increases malignancy of breast cancer cells lines [PDF]

open access: yes, 2017
OXFORD UNIVERSITY: This is a pre-copyedited, author-produced version of an article accepted for publication in Carcinogenesis following peer review. The version of record David Rincón-Fernández, Michael D Culler, Natia Tsomaia, Gema Moreno-Bueno, Raúl M ...
Castaño, Justo P.   +6 more
core   +1 more source

The Role of the Oral Microbiome in Circulating Metabolic Biomarkers and the Influence of Air Pollution

open access: yesOral Diseases, EarlyView.
ABSTRACT Aims The oral microbiome is at the frontline for environmental exposure and plays an important role in human metabolism. This study explores the relationship between PM2.5 exposure, the oral microbiome, and metabolic biomarkers including ghrelin, resistin, and insulin.
Jiajun Luo   +5 more
wiley   +1 more source

In ovo Administration of Ghrelin and Subsequent Prolactin Level in Newly Hatched Chicks

open access: yesThe Journal of Poultry Science, 2011
Ghrelin is a prolactin (PRL)-releasing factor in animal species. The aim of this study was to investigate the effects of in ovo ghrelin administration on plasma PRL levels in hatched chicks. We divided 350 fertilized eggs into 7 groups: group T1 as the
Alireza Lotfi   +4 more
doaj   +1 more source

The role of simulations in consumer experiences and behavior: insights from the grounded cognition theory of desire [PDF]

open access: yes, 2017
What are the mechanisms by which extrinsic and environmental cues affect consumer experiences, desires, and choices? Based on the recent grounded cognition theory of desire, we argue that consumption and reward simulations constitute a central mechanism ...
Barsalou, Lawrence W.   +3 more
core   +1 more source

Ghrelin transport across the blood–brain barrier can occur independently of the growth hormone secretagogue receptor

open access: yesMolecular Metabolism, 2018
Objective: The blood–brain barrier (BBB) regulates the entry of substrates and peptides into the brain. Ghrelin is mainly produced in the stomach but exerts its actions in the central nervous system (CNS) by crossing the BBB.
Elizabeth M. Rhea   +5 more
doaj   +1 more source

The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]

open access: yes, 2015
The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio   +16 more
core   +1 more source

Evaluation of metabolism‐related molecules in rat model of autism spectrum disorders

open access: yesExperimental Physiology, EarlyView.
Abstract Autism spectrum disorders (ASD) are neurodevelopmental pathologies. Investigating both sexes is crucial for understanding sex‐specific manifestations of ASD. This study aims to examine ASD‐like behaviours and metabolic alterations in male and female rats prenatally exposed to valproic acid (VPA).
Süeda Tunçak   +3 more
wiley   +1 more source

Vagal Blocking for Obesity Control : a Possible Mechanism-Of-Action [PDF]

open access: yes, 2016
14 September 2016 Erratum to: Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action Helene Johannessen, David Revesz, Yosuke Kodama, Nikki Cassie, Karolina P Skibicka, Perry Barrett, Suzanne Dickson, Jens Holst, Jens Rehfeld, Geoffrey van ...
Adan, Roger   +14 more
core   +1 more source

The role of agomelatine in appetite regulation and body weight in rats

open access: yesExperimental Physiology, EarlyView.
Abstract The hypothalamic nuclei play a central role in the synthesis of anorexigenic and orexigenic neuropeptides, which are regulated by peripheral hormones, like leptin and ghrelin. Melatonergic receptors (MT1/MT2) are prominently expressed in the arcuate nucleus of the hypothalamus – an essential hub for appetite control – and in peripheral ...
Engin Korkmaz   +3 more
wiley   +1 more source

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