Results 31 to 40 of about 3,121 (172)

The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components [PDF]

, 2014
G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner.
Agnati, Luigi F, Borroto-Escuela, Dasiel O, Brito, Ismel, Di Palma, Michael, Duchou, Jolien, Fuxe, Kjell, Guidolin, Diego, Oflijan, Julia, Rivera, Alicia, Romero-Fernandez, Wilber, Skieterska, Kamila, Suárez-Boomgaard, Diana, Van Craenenbroeck, Kathleen   +12 more
core   +4 more sources

Growth Hormone Secretagogue Receptor (GHSR) Is Elevated in Myocardial Tissues of DMD mdx:utrn−/− Mice, and Correlates Strongly with Inflammatory Markers, and Negatively with Cardiac Function

Cells
Dilated cardiomyopathy affects greater than 1 in 2500 patients worldwide, including those with the neuromuscular disorder Duchenne muscular dystrophy (DMD).
Maedeh Naghibosadat, Andrew McClennan, Margarita Egiian, Reema Flynn-Rizk, Tyler Lalonde, Carlie L. Charron, Akansha Chhabra, Leonard G. Luyt, Savita Dhanvantari, Lisa Hoffman   +9 more
openalex   +3 more sources

GHSR deficiency suppresses neointimal formation in injured mouse arteries [PDF]

Biochemical and Biophysical Research Communications, 2016
Growth hormone secretagogue receptor (GHSR) is involved in appetite regulation and energy homeostasis. In the present study, we examined the role of GHSR in neointimal formation following vascular injury. In the mouse model of femoral artery wire injury, we found that vessel intima-to-media ratio was significantly reduced in GHSR deficiency (GHSR ...
Jing Li, Man Zhang, Mo Wang, Zhipeng Wang, Yahan Liu, Weizhen Zhang, Nanping Wang   +6 more
openalex   +5 more sources

Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]

, 2013
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre, Liposits, Zsolt, Sárvári, Miklós, Vastagh, Csaba   +3 more
core   +2 more sources

The role of ghrelin-responsive mediobasal hypothalamic neurons in mediating feeding responses to fasting

Molecular Metabolism, 2017
Objective: Ghrelin is a stomach-derived hormone that affects food intake and regulates blood glucose. The best-characterized actions of ghrelin are mediated by its binding to and activation of the growth hormone secretagogue receptor (GHSR; ghrelin ...
Bharath K. Mani, Sherri Osborne-Lawrence, Mathieu Mequinion, Sydney Lawrence, Laurent Gautron, Zane B. Andrews, Jeffrey M. Zigman   +6 more
doaj   +1 more source

Neuropeptide receptors as potential antiepileptic drug targets : focus on the ghrelin axis [PDF]

, 2014
Epilepsy is a very serious neurological disorder which is often underrepresented. Around 50 million individuals worldwide have active epilepsy with recurrent seizures and in spite of the medical advances over the years, 30% of these patients remain as ...
Portelli, Jeanelle
core   +1 more source

Exploring the Relationship Between Growth Hormone Secretagogue Receptor (GHSR) Gene and Body Proportions in Bangkok Chickens: Insights from DNA Sequencing and Hin6I Enzyme-Restricted PCR-RFLP Analysis

Jurnal Medik Veteriner
The purpose of this study was to determine the diversity of the growth hormone secretagogue receptor (GHSR) gene and also to analyze the association of the GHSR gene with the body proportions of Bangkok chickens.
Gayuh Syaikhullah, Rosa Tri Hertamawati, M. Adhyatma   +2 more
openalex   +4 more sources

GHSR gene knockout alleviates the liver pathological response in Echinococcus granulosus infection by reducing parasite survival

Veterinary Research
Cystic echinococcosis (CE) is a parasitic disease caused by the larval stage of Echinococcus granulosus, and the immunosuppressive microenvironment exacerbates disease progression.
Jiang Zhu, Tanfang Zhou, Guangfeng Chen, Huijing Gao, Xia Chen, Ayinula Tuohetali, Ya Song, Dongming Pang, Kalibixiati Aimulajiang   +8 more
openalex   +2 more sources

The Developmental Changes of mRNAs Expression Levels of GHSR Gene in Sheep

AASRI Procedia, 2014
Different age group of Male Kazak sheep and Xinjiang fine wool sheep were used in the current study to investigate the developmental changes of GHSR mRNA expression. After measurement of body weight, hypothalamus and pituitary were sampled to extract total RNA for determining the abundance of GHSR mRNA by RT-PCR and real-time PCR. The results indicated
Zhiguo Huang, Chunhui Wei, Huibo Luo, Minghong Bian, Jie Deng, Yanmei Liu   +5 more
openalex   +3 more sources

Edinger-Westphal Nucleus [PDF]

, 2008
This report contains a summary of expression patterns for genes that are enriched in the Edinger-Westphal nucleus (EW) of the midbrain. All data are derived from the Allen Brain Atlas (ABA) in situ hybridization mouse project.
Allen Institute for Brain Science, Angela L. Guillozet-Bongaarts, Josh J. Burnell, Lydia L. Ng   +3 more
core   +2 more sources