Results 51 to 60 of about 3,121 (172)

The ghrelinergic system in zebrafish gonads is suppressed during food unavailability

Aquaculture and Fisheries, 2022
Ghrelin is an appetite stimulatory peptide that regulates reproduction in vertebrates. The acylation of ghrelin by ghrelin-O-acyltransferase (Goat) is essential for most of its functions. The ghrelinergic system (ghrelin, ghrelin receptor [Ghsr] and Goat)
Azadeh Hatef, Jithine Jayakumar Rajeswari, Suraj Unniappan   +2 more
doaj   +1 more source

Area Postrema [PDF]

, 2008
This report contains a gene expression summary of the area postrema (AP), derived from the "Allen Brain Atlas":http://www.brain-map.org/welcome.do;jsessionid=EDE40ADC940845D169DE378ADC9B71BD (ABA) in-situ hybridization (ISH) mouse data set ...
Allen Institute for Brain Science, John A. Morris, Katie J. Glattfelder, Lydia L. Ng   +3 more
core   +2 more sources

Ghrelin Modulates Physiologic and Pathologic Retinal Angiogenesis through GHSR-1a [PDF]

Investigative Opthalmology & Visual Science, 2011
Vascular degeneration and the ensuing abnormal vascular proliferation are central to proliferative retinopathies. Given the metabolic discordance associated with these diseases, the authors explored the role of ghrelin and its growth hormone secretagogue receptor 1a (GHSR-1a) in proliferative retinopathy.In a rat model of oxygen-induced retinopathy ...
Lois E.H. Smith, Karine Zaniolo, Ankush Madaan, Emilie Picard, Pierre Lachapelle, Sophie Tremblay, Sylvain Chemtob, Joseph A. Mancini, Przemyslaw Sapieha, Tang Zhu, Zhuo Shao, Andreas Stahl, Andreas Stahl, Martine Blais, Pierre Hardy, Huy Ong   +15 more
openaire   +5 more sources

Association Analysis of the Leptin and Ghrelin Receptor Gene Polymorphism in the Human with BMI

Scientific Papers Animal Science and Biotechnologies, 2023
The aim of this work was identification of Leptin and Ghrelin receptor gene polymorphism in the population. Leptin is a product of obese (ob) gene expression that plays a role in energy metabolism and body weight.
Zuzana Lieskovská, Anna Trakovická, Anton Kováčik, Tomáš Minarovič, Alica Rafayová   +4 more
doaj  

Ghrelin regulates glucose and glutamate transporters in hypothalamic astrocytes [PDF]

, 2016
Hypothalamic astrocytes can respond to metabolic signals, such as leptin and insulin, to modulate adjacent neuronal circuits and systemic metabolism. Ghrelin regulates appetite, adiposity and glucose metabolism, but little is known regarding the response
Argente, Jesús, Argente-Arizón, Pilar, Castro-González, David, Ceballos, María L., Chowen, Julie Ann, Dickson, Suzanne L., Díaz, Francisca, Frago, Laura M., Freire-Regatillo, Alejandra, Fuente-Martín, Esther, García-Cáceres, Cristina, Granado. Miriam   +11 more
core   +2 more sources

Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance. [PDF]

PLoS ONE, 2008
Ghrelin may influence the development of obesity through its role in the control of energy balance, food intake, and regulation of body weight. The effects of ghrelin are mediated via the growth hormone secretagogue receptor (GHSR).We genotyped 7 single ...
Ursula Mager, Tatjana Degenhardt, Leena Pulkkinen, Marjukka Kolehmainen, Anna-Maija Tolppanen, Jaana Lindström, Johan G Eriksson, Carsten Carlberg, Jaakko Tuomilehto, Matti Uusitupa, Finnish Diabetes Prevention Study Group   +10 more
doaj   +1 more source

From the stomach to locus coeruleus: new neural substrate for ghrelin’s effects on ingestive, motivated and anxiety-like behaviors

Frontiers in Pharmacology, 2023
Ghrelin, a stomach-derived orexigenic hormone, has a well-established role in energy homeostasis, food reward, and emotionality. Noradrenergic neurons of the locus coeruleus (LC) are known to play an important role in arousal, emotion, cognition, but ...
Ivana Maric, Ivana Maric, Lorena López-Ferreras, Yashaswini Bhat, Mohammed Asker, Stina Börchers, Stina Börchers, Lauren Bellfy, Lauren Bellfy, Suyeun Byun, Janine L. Kwapis, Janine L. Kwapis, Karolina P. Skibicka, Karolina P. Skibicka, Karolina P. Skibicka   +14 more
doaj   +1 more source

Ghrelin [PDF]

, 2015
This work was supported by grants from the NIH (DP2DK105570-01 and 2P30DK046200 to MLA, DK21397 to HJG, K01DK098319 to KMH, K01MH091222 to LH, DK093848 to RJS, R01DK082590 to LS, R01DK097550 to JT, RO1 DK 076037 to MOT, R01DA024680 and R01MH085298 to ...
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core   +5 more sources

Sodium is a negative allosteric regulator of the ghrelin receptor

Cell Reports, 2023
Summary: The functional properties of G protein-coupled receptors (GPCRs) are intimately associated with the different components in their cellular environment.
Guillaume Ferré, Antoniel A.S. Gomes, Maxime Louet, Marjorie Damian, Paulo M. Bisch, Olivier Saurel, Nicolas Floquet, Alain Milon, Jean-Louis Banères   +8 more
doaj   +1 more source

Obesity-Induced PVAT Dysfunction and Atherosclerosis Development: The Role of GHSR-1a in Increased Macrophage Infiltration and Adipocytokine Secretion

Journal of Cardiovascular Development and Disease
In obesity, recent research revealed that increased expression of the growth hormone secretagogue receptor (GHSR) in macrophages plays a pivotal role in the development of meta-inflammation, promoting macrophage infiltration and pro-inflammatory ...
Sorin Nicolae Peiu, Florin Zugun‐Eloae, Bogdan Stoica, Ecaterina Anisie, Diana Gabriela Iosep, Mihai Danciu, Iustina Silivestru-Crețu, Fawzy Akad, Andrei Nicolae Avadanei, Laura Condur, Radu Florin Popa, Veronica Mocanu   +11 more
openalex   +3 more sources