Results 51 to 60 of about 8,260 (216)
An atomic look at the interface of GHSR and its partners
Computational and Structural Biotechnology JournalG protein-coupled receptors (GPCRs) regulate cellular activity by transducing external signals and selectively coupling them to intracellular partners. Ghrelin receptor (GHSR) has garnered significant interest over the past decade owing to its diverse functional roles.Carlos A.V. Barreto, Irina S. Moreiraopenalex +3 more sourcesVariations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance. [PDF]
PLoS ONE, 2008 Ghrelin may influence the development of obesity through its role in the control of energy balance, food intake, and regulation of body weight. The effects of ghrelin are mediated via the growth hormone secretagogue receptor (GHSR).We genotyped 7 single ...Ursula Mager, Tatjana Degenhardt, Leena Pulkkinen, Marjukka Kolehmainen, Anna-Maija Tolppanen, Jaana Lindström, Johan G Eriksson, Carsten Carlberg, Jaakko Tuomilehto, Matti Uusitupa, Finnish Diabetes Prevention Study Group +10 moredoaj +1 more sourceGhrelin regulates glucose and glutamate transporters in hypothalamic astrocytes [PDF]
, 2016 Hypothalamic astrocytes can respond to metabolic signals, such as leptin and insulin, to modulate adjacent neuronal circuits and systemic metabolism. Ghrelin regulates appetite, adiposity and glucose metabolism, but little is known regarding the response Argente, Jesús, Argente-Arizón, Pilar, Castro-González, David, Ceballos, María L., Chowen, Julie Ann, Dickson, Suzanne L., Díaz, Francisca, Frago, Laura M., Freire-Regatillo, Alejandra, Fuente-Martín, Esther, García-Cáceres, Cristina, Granado. Miriam +11 morecore +2 more sourcesEscalation in high fat intake in a binge eating model differentially engages dopamine neurons of the ventral tegmental area and requires ghrelin signaling [PDF]
, 2015 Binge eating is a behavior observed in a variety of human eating disorders. Ad libitum fed rodents daily and time-limited exposed to a high-fat diet (HFD) display robust binge eating events that gradually escalate over the initial accesses.Cornejo, María P., De Francesco, Pablo, Perelló, Mario, Reynaldo, Mirta Beatriz, Valdivia Torres, Lesly Spring +4 morecore +2 more sourcesGhrelin [PDF]
, 2015 This work was supported by grants from the NIH (DP2DK105570-01 and
2P30DK046200 to MLA, DK21397 to HJG, K01DK098319 to KMH, K01MH091222 to
LH, DK093848 to RJS, R01DK082590 to LS, R01DK097550 to JT, RO1 DK 076037 to
MOT, R01DA024680 and R01MH085298 to ...Abizaid, Adachi, Adeghate, Akashi, Al Massadi, Alvarez-Crespo, Anderson, Andrews, Andrews, Ang, Anker, Armand, Arnold, Arosio, Arvat, Arvat, Asakawa, Asakawa, Ashby, Atalayer, Avau, Bach, Bailey, Baldanzi, Barazzoni, Barim, Barnett, Beiras-Fernandez, Berridge, Berulava, Blake, Blatnik, Blum, Bohdjalian, Bose, Bowers, Bowers, Briggs, Briggs, Broglio, Broglio, Broglio, Broglio, Buscher, Cai, Callahan, Camilleri, Carlini, Carlini, Cecil, Cederberg, Chambers, Chapman, Chen, Chen, Cheng, Chuang, Chuang, Chuang, Cowley, Crum, Cummings, Cummings, Cummings, Cummings, Cummings, Currie, Currow, Damian, Dass, Date, Date, de la Cour, De Smet, De Smet, De Vriese, Deboer, Delhanty, Delhanty, DelParigi, den Hoed, Depoortere, Dezaki, Dezaki, Dezaki, Diano, Dickson, Dickson, Dickson, Dietrich, Dimitriadis, Dina, Dixit, Dornonville de la Cour, Druce, Egido, Engelstoft, Espelund, Falken, Faulconbridge, Faulconbridge, Faulconbridge, Ferrini, Filigheddu, Flanagan, Foster-Schubert, Frayling, Frecka, Fusco, Gagnon, Gagnon, Geliebter, Geliebter, Giordano, Gnanapavan, Goldstein, Goldstone, Granata, Granata, Granata, Granata, Granata, Guan, Guido, Gutierrez, Hady, Hansson, Hardy, Hass, Hataya, Heppner, Heppner, Heppner, Hess, Hewson, Hinney, Holsen, Horvath, Hosoda, Hotta, Hou, Howard, Huda, Inoue, Irako, Iwakura, Iwakura, Janssen, Janssen, Jerlhag, Jerlhag, Jerlhag, Jerlhag, Jerlhag, Jerlhag, Jiang, Kamiji, Kanoski, Kanoski, Karra, Kawahara, Kern, Kirchner, Koch, Kojima, Kojima, Kola, Kola, Korbonits, Korbonits, Korbonits, Korbonits, Kotidis, Koutkia, Kroemer, Kurt, Kwon Jeong, Lage, Lainscak, Lall, Lanfranco, Langer, Lango Allen, Lauria, Lawrence, Lee, Lefkowitz, Lejeune, Lenk, Leung, Levin, Levitzki, Li, Li, Li, Libe, Lim, Lin, Liu, Liu, Longo, Lopez, Lu, Lund, Lutter, Malandrino, Malik, Mani, Mano-Otagiri, Mano-Otagiri, Martins, Martos-Moreno, Masuda, McFarlane, Mericq, Meyer, Miki, Mizutani, Momany, Monteleone, Monteleone, Monteleone, Moon, Muller, Mundinger, Murphy, Murray, Müller, Nagaya, Nagaya, Nagaya, Nagaya, Nakazato, Naleid, Nass, Neary, Nederkoorn, Nishi, Ohgusu, Okumura, Olszewski, Olszewski, Overduin, Palus, Palus, Pantel, Park, Patchett, Peino, Perello, Perez-Tilve, Perez-Tilve, Peterli, Pfluger, Popovic, Porporato, Prudom, Qader, Quarta, Ravussin, Reed, Reimer, Rizza, Rizzo, Romero-Pico, Romero-Pico, Sakata, Sakata, Sakata, Sakata, Sakkou, Salamone, Salehi, Schaeffer, Schellekens, Schmid, Scott, Seoane, Seoane, Sha, Shiiya, Shin, Shin, Shrestha, Shuto, Simonian, Skibicka, Skibicka, Skibicka, Skibicka, Smith, Soriano-Guillen, Speakman, Spencer, Spencer, Stefater, Strassburg, Sun, Sun, Sun, Sun, Szentirmai, Szentirmai, Szentirmai, Szentirmai, Tack, Takaya, Tanofsky-Kraff, Tassone, Theander-Carrillo, Thompson, Timpson, Tolle, Tomasetto, Tong, Tong, Tong, Toshinai, Tschop, Tschop, Tschop, Tsubone, Uchida, Ueberberg, van der Lely, Van der Ploeg, Velasquez, Veldhuis, Verhagen, Verhulst, Vila, Volante, Volante, von Haehling, Walker, Wang, Wardle, Wardle, Weikel, Wellman, Willesen, Williams, Williams, Wortley, Wortley, Wren, Wynne, Yamada, Yang, Yang, Yasuda, Zhang, Zhang, Zhang, Zhao, Zhao, Zigman, Zigman, Zorrilla +358 morecore +5 more sourcesFamily and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity. [PDF]
PLoS ONE, 2010 The growth hormone secretagogue receptor (GHSR) is mediating hunger sensation when stimulated by its natural ligand ghrelin. In the present study, we tested the hypothesis that common and rare variation in the GHSR locus are related to increased ...Anette P Gjesing, Lesli H Larsen, Signe S Torekov, Irena Aldhoon Hainerová, Rahul Kapur, Anders Johansen, Anders Albrechtsen, Sylvia Boj, Birgitte Holst, Angela Harper, Søren A Urhammer, Knut Borch-Johnsen, Charlotta Pisinger, Søren M Echwald, Hans Eiberg, Arne Astrup, Jan Lebl, Jorge Ferrer, Thue W Schwartz, Torben Hansen, Oluf Pedersen +20 moredoaj +1 more sourceFrom the stomach to locus coeruleus: new neural substrate for ghrelin’s effects on ingestive, motivated and anxiety-like behaviors
Frontiers in Pharmacology, 2023 Ghrelin, a stomach-derived orexigenic hormone, has a well-established role in energy homeostasis, food reward, and emotionality. Noradrenergic neurons of the locus coeruleus (LC) are known to play an important role in arousal, emotion, cognition, but ...Ivana Maric, Ivana Maric, Lorena López-Ferreras, Yashaswini Bhat, Mohammed Asker, Stina Börchers, Stina Börchers, Lauren Bellfy, Lauren Bellfy, Suyeun Byun, Janine L. Kwapis, Janine L. Kwapis, Karolina P. Skibicka, Karolina P. Skibicka, Karolina P. Skibicka +14 moredoaj +1 more sourceGhrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease [PDF]
, 2016 Jacqeline Bayliss, Romana Stark, Moyra Lemus, Vanessa Santos, Aiysha Thompson, Daniel Rees, Sandra Galic, John Elsworth, Bruce Kemp, Jeffrey Davies, and Zane ...Andrews, Zane B., Bayliss, Jacqueline A., Davies, Jeffrey S., Elsworth, John D., Galic, Sandra, Kemp, Bruce Ernest, Lemus, Moyra B., Rees, Daniel J., Santos, Vanessa V., Stark, Romana, Thompson, Aiysha +10 morecore +2 more sources
