Results 91 to 100 of about 40,389 (237)

Pulsatile lipid vesicles under osmotic stress [PDF]

Biophysical Journal 112, 1682-1691, April 25, 2017, 2016
The response of lipid bilayers to osmotic stress is an important part of cellular function. Previously, in [Oglecka et al. 2014], we reported that cell-sized giant unilamellar vesicles (GUVs) exposed to hypotonic media, respond to the osmotic assault by undergoing a cyclical sequence of swelling and bursting events, coupled to the membrane's ...
arxiv   +1 more source

Bioinspired Cationic Antimicrobial Polymers

Angewandte Chemie International Edition, EarlyView.
A review about membrane active cationic polymers with antimicrobial properties. A focus is laid on polymeric architecture, stimuli‐responsive antimicrobial polymers, as well as synergistic effects of polymers, and other compounds. Abstract Antibiotics are an essential tool of modern medicine, which is critically endangered by the spread of ...
Heliya Javadi, Anne‐Catherine Lehnen, Matthias Hartlieb   +2 more
wiley   +1 more source

Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to the Presence of Cholesterol

Molecules, 2015
In the present investigation we studied the molecular mechanisms of the monodesmosidic saponin digitonin on natural and artificial membranes. We measured the hemolytic activity of digitonin on red blood cells (RBCs). Also different lipid membrane models (
Ikhwan Resmala Sudji, Yamunadevi Subburaj, Nataliya Frenkel, Ana J. García-Sáez, Michael Wink   +4 more
doaj   +1 more source

Non‐Amphiphilic Antimicrobial Polymers

Angewandte Chemie International Edition, Accepted Article.
Antimicrobial resistance (AMR) is a severe threat to modern health care and must be addressed to prevent millions of deaths in the coming decades. Antimicrobial polymers (APs) do not provoke resistances and are promising alternatives to conventional antibiotics. Classic APs possess an amphiphilic structure (cationic and hydrophobic). Herein we question
Alain M. Bapolisi, Anne-Catherine Lehnen, Martin Wolff, Jana Kramer, Sergio Kogikoski, René Steinbrecher, Nicole Michler, Andreas Kiesow, Ilko Bald, Martina Obry, Sebastian Kersting, Till Stensitzki, Henrike M. Müller-Werkmeister, Meike N. Leiske, Salvatore Chiantia, Matthias Hartlieb   +15 more
wiley   +1 more source

Membrane shape as a reporter for applied forces [PDF]

, 2008
Recent advances have enabled 3-dimensional reconstructions of biological structures in vivo, ranging in size and complexity from single proteins to multicellular structures. In particular, tomography and confocal microscopy have been exploited to capture
Antonny, Canham, Cheng, E. L. Peterson, Evans, Fertuck, Frey, Gerlich, H. J. Lee, Heinrich, Jenkins, Kusumi, Ledesma, Mills, Neuman, P. A. Wiggins, R. Phillips, Rawicz, Razani, Rodriguez-Boulan, Sheetz, Singer, Sougrat, Tian, Unwin, Upadhyaya, Vale, W. S. Klug, Waterman-Storer, Waugh, Waugh   +30 more
core   +2 more sources

Design and Manufacture of a Low-Cost Microfluidic System for the Synthesis of Giant Liposomes for the Encapsulation of Yeast Homologues: Applications in the Screening of Membrane-Active Peptide Libraries

Micromachines, 2021
The discovery of new membrane-active peptides (MAPs) is an area of considerable interest in modern biotechnology considering their ample applicability in several fields ranging from the development of novel delivery vehicles (via cell-penetrating ...
Saúl C. Gómez, Valentina Quezada, Isabella Quiroz, Carolina Muñoz-Camargo, Johann F. Osma, Luis H. Reyes, Juan C. Cruz   +6 more
doaj   +1 more source

Selective Light‐Driven CO2 to CO Reduction by a [FeFe]‐Hydrogenase Mimic in Water

ChemCatChem, EarlyView.
Highly selective light‐driven CO2 conversion to CO is achieved using an [FeFe]‐hydrogenase‐inspired molecular dyad (PS‐CAT) acting simultaneously as photosensitizer and catalyst. The presence of water as a solvent is important for such selectivity. Assembling the PS‐CAT in the hydrophobic part of lipid bilayers of liposomes allows the use of water as a
Amir Abbas, Chizuru Kasahara, Yongchao Chen, Martin Oschatz, Stefanie Gräfe, Wolfgang Weigand, Andrea Pannwitz   +6 more
wiley   +1 more source

Shaping Giant Membrane Vesicles in 3D-Printed Protein Hydrogel Cages

, 2020
Giant unilamellar phospholipid vesicles are attractive starting points for constructing minimal living cells from the bottom-up. Their membranes are compatible with many physiologically functional modules and act as selective barriers, while retaining a ...
Eto, H., Franquelim, H., Heymann, M., Jia, H., Litschel, T., Schwille, P.   +5 more
core   +1 more source

Study of the Interaction of a Novel Semi-Synthetic Peptide with Model Lipid Membranes

Membranes, 2020
Most linear peptides directly interact with membranes, but the mechanisms of interaction are far from being completely understood. Here, we present an investigation of the membrane interactions of a designed peptide containing a non-natural, synthetic ...
Lucia Sessa, Simona Concilio, Peter Walde, Tom Robinson, Petra S. Dittrich, Amalia Porta, Barbara Panunzi, Ugo Caruso, Stefano Piotto   +8 more
doaj   +1 more source

Sphingomyelinase D activity in model membranes: structural effects of in situ generation of ceramide-1-phosphate. [PDF]

PLoS ONE, 2012
The toxicity of Loxosceles spider venom has been attributed to a rare enzyme, sphingomyelinase D, which transforms sphingomyelin to ceramide-1-phosphate. The bases of its inflammatory and dermonecrotic activity, however, remain unclear.
Roberto P Stock, Jonathan Brewer, Kerstin Wagner, Blanca Ramos-Cerrillo, Lars Duelund, Kit Drescher Jernshøj, Lars Folke Olsen, Luis A Bagatolli   +7 more
doaj   +1 more source