Results 91 to 100 of about 12,701 (197)
What's new? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan +14 more
wiley +1 more source
Study of the Interaction of a Novel Semi-Synthetic Peptide with Model Lipid Membranes
Most linear peptides directly interact with membranes, but the mechanisms of interaction are far from being completely understood. Here, we present an investigation of the membrane interactions of a designed peptide containing a non-natural, synthetic ...
Lucia Sessa +8 more
doaj +1 more source
The Influence of high pressure on the bending rigidity of model membranes [PDF]
Curvature is a fundamental lipid membrane property that influences many membrane-mediated biological processes and dynamic soft materials. One of the key parameters that determines the energetics of curvature change is the membrane bending rigidity ...
Brooks, NJ +3 more
core +2 more sources
Aqueous self‐assembly of a 2‐nitrobenzyl‐functionalized glucosamine derivative leads to the formation of photo‐responsive glyco‐microfibers via cooperative noncovalent interactions, primarily driven by π–π stacking and hydrogen bonding. Upon photo‐irradiation, the glyco‐microfibers undergo dis‐assembly even within confined water‐in‐oil microdroplets ...
Fumiko Nakagawa +7 more
wiley +1 more source
Direct measurement of DNA-mediated adhesion between lipid bilayers
Multivalent interactions between deformable mesoscopic units are ubiquitous in biology, where membrane macromolecules mediate the interactions between neighbouring living cells and between cells and solid substrates.
Cicuta, P. +5 more
core +1 more source
Native silica nanoparticles are powerful membrane disruptors [PDF]
Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I. +3 more
core +1 more source
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
Membranaktive Peptide (MAPs) wie zellpenetrierende Peptide (CPPs) und antimikrobielle Peptide (AMPs) können Lipidmembranen durchdringen und Membranporen bilden. Die Kombination aus einem Farbstoff‐Efflux‐Assay und einem supramolekularen Tandem‐Membran‐Assay in einem Zweikanalformat ermöglicht eine fortgeschrittene mechanistische Charakterisierung und ...
Mohammad A. Alnajjar +8 more
wiley +1 more source
A novel minimal in vitro system for analyzing HIV-1 Gag mediated budding
A biomimetic minimalist model membrane was used to study the mechanism and kinetics of cell-free in vitro HIV-1 Gag budding from a giant unilamellar vesicle (GUV).
Gill, Sarjeet +7 more
core +1 more source
Membrane‐active peptides (MAPs) such as cell‐penetrating peptides (CPPs) and antimicrobial peptides (AMPs) can translocate across lipid membranes and create membrane pores. The combination of a dye efflux and a supramolecular tandem membrane assay in a dual‐channel format enables an advanced mechanistic characterization and an exploration of the ...
Mohammad A. Alnajjar +8 more
wiley +1 more source

