Results 11 to 20 of about 113,785 (252)

Giant virus diversity and host interactions through global metagenomics. [PDF]

open access: yesNature, 2020
AbstractOur current knowledge about nucleocytoplasmic large DNA viruses (NCLDVs) is largely derived from viral isolates that are co-cultivated with protists and algae. Here we reconstructed 2,074 NCLDV genomes from sampling sites across the globe by building on the rapidly increasing amount of publicly available metagenome data.
Schulz F   +10 more
europepmc   +7 more sources

Giant variations in giant virus genome packaging

open access: yesTrends in Biochemical Sciences, 2023
Giant viruses (Nucleocytoviricota) have a largely conserved lifecycle, yet how they cram their large genomes into viral capsids is mostly unknown. The major capsid protein and the packaging ATPase (pATPase) comprise a highly conserved morphogenesis module in giant viruses, yet some giant viruses dispense with an icosahedral capsid, and others encode ...
Paul B. Talbert   +2 more
openaire   +2 more sources

Varicella zoster virus and giant cell arteritis [PDF]

open access: yesCurrent Opinion in Infectious Diseases, 2016
Giant cell arteritis (GCA) is a serious disease and the most common cause of vasculitis in the elderly. Here, studies describing the recent discovery of varicella zoster virus (VZV) in the temporal arteries of patients with GCA are reviewed.GCA is characterized by severe headache/head pain and scalp tenderness.
Don, Gilden, Maria A, Nagel
  +8 more sources

A giant virus infecting the amoeboflagellate Naegleria. [PDF]

open access: yesNat Commun
AbstractGiant viruses (Nucleocytoviricota) are significant lethality agents of various eukaryotic hosts. Although metagenomics indicates their ubiquitous distribution, available giant virus isolates are restricted to a very small number of protist and algal hosts.
Arthofer P   +12 more
europepmc   +7 more sources

Structural and Proteomic Studies of the Aureococcus anophagefferens Virus Demonstrate a Global Distribution of Virus-Encoded Carbohydrate Processing

open access: yesFrontiers in Microbiology, 2020
Viruses modulate the function(s) of environmentally relevant microbial populations, yet considerations of the metabolic capabilities of individual virus particles themselves are rare. We used shotgun proteomics to quantitatively identify 43 virus-encoded
Eric R. Gann   +6 more
doaj   +1 more source

Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages [PDF]

open access: yes, 2020
Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage-bacteria interactions and is a candidate for phage therapy applications.
Blasdel, Bob G.   +9 more
core   +1 more source

Relapse of polymyalgia rheumatica following adjuvanted influenza vaccine: A case-based review [PDF]

open access: yes, 2020
Polymyalgia rheumatica (PMR) is the most common inflammatory rheumatological condition affecting individuals aged >50 years. There have been rare reports of PMR and other vasculitides developing within 3 months of influenza vaccination.
Bassendine, Margaret F., Bridge, Simon
core   +1 more source

A Brief History of Giant Viruses’ Studies in Brazilian Biomes

open access: yesViruses, 2022
Almost two decades after the isolation of the first amoebal giant viruses, indubitably the discovery of these entities has deeply affected the current scientific knowledge on the virosphere. Much has been uncovered since then: viruses can now acknowledge
Paulo Victor M. Boratto   +16 more
doaj   +1 more source

Near-atomic structure of a giant virus. [PDF]

open access: yesNat Commun, 2019
Abstract Although the nucleocytoplasmic large DNA viruses (NCLDVs) are one of the largest group of viruses that infect many eukaryotic hosts, the near-atomic resolution structures of these viruses have remained unknown. Here we describe a 3.5 Å resolution icosahedrally averaged capsid structure of Paramecium bursaria chlorella virus 1
Fang Q   +11 more
europepmc   +5 more sources

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a

open access: yesDermatology Practical & Conceptual, 2014
Background: Multinucleated giant cells in the epidermis can either be epithelial or histiocytic. Epithelial multinucleated giant cells are most often associated with herpes virus infections.
Philip R. Cohen   +2 more
doaj   +1 more source

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