Results 21 to 30 of about 113,785 (252)

An Update on Eukaryotic Viruses Revived from Ancient Permafrost

Viruses, 2023
One quarter of the Northern hemisphere is underlain by permanently frozen ground, referred to as permafrost. Due to climate warming, irreversibly thawing permafrost is releasing organic matter frozen for up to a million years, most of which decomposes ...
Jean-Marie Alempic, Audrey Lartigue, Artemiy E. Goncharov, Guido Grosse, Jens Strauss, Alexey N. Tikhonov, Alexander N. Fedorov, Olivier Poirot, Matthieu Legendre, Sébastien Santini, Chantal Abergel, Jean-Michel Claverie   +11 more
doaj   +1 more source

Cryptic infection of a giant virus in a unicellular green alga. [PDF]

Science
Erazo-Garcia MP, Sheyn U, Barth ZK, Craig RJ, Wessman P, Jivaji AM, Ray WK, Svensson-Coelho M, Cornwallis CK, Rengefors K, Brussaard CPD, Moniruzzaman M, Aylward FO.   +12 more
europepmc   +2 more sources

Evolutionary Dynamics of Giant Viruses and their Virophages [PDF]

, 2013
Giant viruses contain large genomes, encode many proteins atypical for viruses, replicate in large viral factories, and tend to infect protists. The giant virus replication factories can in turn be infected by so called virophages, which are smaller ...
Anderson, Beddington, Briggs, Claverie, Claverie, Claverie, Claverie, Colson, Culley, Desnues, Desnues, Desnues, Fischer, Fischer, Forterre, Gillespie, Herrero-Uribe, Hochberg, Holt, Iyer, Koonin, Krupovic, Lawrence, May, McCallum, Nowak, Pearson, Raoult, Raoult, Roy, Ruiz-Saenz, Scola, Scola, Scola, Sun, Suzan-Monti, Wodarz, Yamada, Yau, Zhang   +39 more
core   +2 more sources

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

Quantitative Infection Dynamics of Cafeteria Roenbergensis Virus

Viruses, 2018
The discovery of giant viruses in unicellular eukaryotic hosts has raised new questions on the nature of viral life. Although many steps in the infection cycle of giant viruses have been identified, the quantitative life history traits associated with ...
Bradford P. Taylor, Joshua S. Weitz, Corina P. D. Brussaard, Matthias G. Fischer   +3 more
doaj   +1 more source

Coral Bleaching Phenotypes Associated With Differential Abundances of Nucleocytoplasmic Large DNA Viruses

Frontiers in Marine Science, 2020
Eukaryotic viruses and bacteriophage have been implicated in disease and bleaching in corals, but the compositional and functional diversity of these viruses in healthy and compromised hosts remains underexplored. To investigate whether viral assemblages
Adriana Messyasz, Adriana Messyasz, Stephanie M. Rosales, Stephanie M. Rosales, Stephanie M. Rosales, Ryan S. Mueller, Teresa Sawyer, Adrienne M. S. Correa, Andrew R. Thurber, Andrew R. Thurber, Rebecca Vega Thurber   +10 more
doaj   +1 more source

The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield

eLife, 2022
Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling the ~0.5 µm icosahedral capsids. Cryo-electron microscopy, cryo-electron
Alejandro Villalta, Alain Schmitt, Leandro F Estrozi, Emmanuelle RJ Quemin, Jean-Marie Alempic, Audrey Lartigue, Vojtěch Pražák, Lucid Belmudes, Daven Vasishtan, Agathe MG Colmant, Flora A Honoré, Yohann Couté, Kay Grünewald, Chantal Abergel   +13 more
doaj   +1 more source

Structural and Proteomic Characterization of the Initiation of Giant Virus Infection. [PDF]

Cell, 2020
Schrad JR, Abrahão JS, Cortines JR, Parent KN.   +3 more
europepmc   +2 more sources

Clinical features of varicella-zoster virus infection [PDF]

, 2018
Varicella-zoster virus (VZV) is a pathogenic human herpes virus that causes varicella (chickenpox) as a primary infection, following which it becomes latent in peripheral ganglia.
Gershon, Anne A., Kennedy, Peter G.E.
core   +1 more source

Mimivirus and the emerging concept of “giant” virus [PDF]

Virus Research, 2006
Submitted to Virus ...
Claverie, Jean-Michel, Ogata, Hiroyuki, Audic, Stéphane, Abergel, Chantal, Fournier, Pierre-Edouard, Suhre, Karsten   +5 more
openaire   +3 more sources