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Structural and Proteomic Characterization of the Initiation of Giant Virus Infection. [PDF]
Since their discovery, giant viruses have expanded our understanding of the principles of virology. Due to their gargantuan size and complexity, little is known about the life cycles of these viruses. To answer outstanding questions regarding giant virus
Schrad JR +3 more
europepmc +2 more sources
MG-Digger: an automated pipeline to search for giant virus-related sequences in metagenomes
The number of metagenomic studies conducted each year is growing dramatically. Storage and analysis of such big data is difficult and time-consuming. Interestingly, analysis shows that environmental and human metagenomes include a significant amount of ...
Jonathan eVerneau +4 more
doaj +2 more sources
Usurpativirus massiliensis, a new giant virus related to clandestinovirus [PDF]
Giant virus discovery in 2003 revolutionized the virus paradigm. In 2015, we introduced a new host, Vermamoeba vermiformis, that led to the discovery of Faustovirus, Orpheovirus and two giant viruses (Clandestinovirus and a faustovirus) having distinct ...
Julien Andreani +6 more
doaj +2 more sources
A virophage cross-species infection through mutant selection represses giant virus propagation, promoting host cell survival. [PDF]
Virus adaptation to new hosts is a major cause of infectious disease emergence. This mechanism has been intensively studied in the context of zoonotic virus spillover, due to its impact on global health.
Mougari S +6 more
europepmc +2 more sources
Asfarviruses and Closely Related Giant Viruses
Acanthamoeba polyphaga mimivirus, so called because of its “mimicking microbe”, was discovered in 2003 and was the founding member of the first family of giant viruses isolated from amoeba.
Sihem Hannat +3 more
doaj +1 more source
Varicella zoster virus and giant cell arteritis [PDF]
Giant cell arteritis (GCA) is a serious disease and the most common cause of vasculitis in the elderly. Here, studies describing the recent discovery of varicella zoster virus (VZV) in the temporal arteries of patients with GCA are reviewed.GCA is characterized by severe headache/head pain and scalp tenderness.
Don, Gilden, Maria A, Nagel
+8 more sources
Giant virus biology and diversity in the era of genome-resolved metagenomics
The discovery of giant viruses, with capsids as large as some bacteria, megabase-range genomes and a variety of traits typically found only in cellular organisms, was one of the most remarkable breakthroughs in biology.
Frederik Schulz, C. Abergel, T. Woyke
semanticscholar +1 more source
Amazing structural diversity of giant virus-like particles in forest soil
Large DNA viruses of the phylum Nucleocytoviricota infect diverse eukaryotic hosts from protists to humans, with profound consequences for aquatic and terrestrial ecosystems.
M. Fischer +2 more
semanticscholar +1 more source
Viruses of the phylum Nucleocytoviricota, often referred to as “giant viruses,” are prevalent in various environments around the globe and play significant roles in shaping eukaryotic diversity and activities in global ecosystems.
Anh D. Ha, F. Aylward
semanticscholar +1 more source
Viruses modulate the function(s) of environmentally relevant microbial populations, yet considerations of the metabolic capabilities of individual virus particles themselves are rare. We used shotgun proteomics to quantitatively identify 43 virus-encoded
Eric R. Gann +6 more
doaj +1 more source

