Results 31 to 40 of about 114,906 (281)

Giant virus diversity and host interactions through global metagenomics. [PDF]

Nature, 2020
AbstractOur current knowledge about nucleocytoplasmic large DNA viruses (NCLDVs) is largely derived from viral isolates that are co-cultivated with protists and algae. Here we reconstructed 2,074 NCLDV genomes from sampling sites across the globe by building on the rapidly increasing amount of publicly available metagenome data.
Schulz F, Roux S, Paez-Espino D, Jungbluth S, Walsh DA, Denef VJ, McMahon KD, Konstantinidis KT, Eloe-Fadrosh EA, Kyrpides NC, Woyke T.   +10 more
europepmc   +6 more sources

New Brazilian giant viruses isolation from environmental samples using a panel of protozoa.

Frontiers in Microbiology, 2015
The Megavirales are a newly described order capable of infecting different types of eukaryotic hosts. For the most part, the natural host is unknown.
Fábio Pio Dornas, Fábio Pio Dornas, Jacques Yaacoub Bou Khalil, Isabelle ePagnier, Didier eRaoult, Jonatas eAbrahao, Bernard eLa Scola   +6 more
doaj   +1 more source

How Tupanvirus Degrades the Ribosomal RNA of Its Amoebal Host? The Ribonuclease T2 Track

Frontiers in Microbiology, 2020
Tupanviruses are giant viruses recently discovered in Brazil from extreme environments: Tupanvirus soda lake (TPV-SL) and Tupanvirus deep ocean (TPV-DO).
Clara Rolland, Clara Rolland, Bernard La Scola, Bernard La Scola, Anthony Levasseur, Anthony Levasseur, Anthony Levasseur   +6 more
doaj   +1 more source

Pathogenesis of polymyalgia rheumatica [PDF]

, 2018
Polymyalgia rheumatica (PMR) is a chronic, inflammatory disorder of unknown cause, almost exclusively occurring in people aged over 50 and often associated with giant cell arteritis.
Ciccia F., Ferrante A., Guggino G., Macaluso F., Triolo G.   +4 more
core   +1 more source

Respiratory syncytial virus: a sleeping giant? [PDF]

European Respiratory Journal, 2007
The study by Jansen et al. 1 in the present issue of the European Respiratory Journal focuses on the impact of influenza and respiratory syncytial virus (RSV) on mortality and hospital admissions. As in many other similar publications, it emphasises the significance of RSV (and influenza) in all age groups and not just children, in whom the impact is ...
D. M. Fleming, A. J. Elliot
openaire   +1 more source

Hidden diversity of soil giant viruses

Nature Communications, 2018
Current knowledge of giant virus diversity is largely based on samples from aquatic environments. Here the authors employ cultivation-independent metagenomics and mini-metagenomics on forest soil and identify 16 novel giant virus genomes, some of which ...
Frederik Schulz, Lauren Alteio, Danielle Goudeau, Elizabeth M. Ryan, Feiqiao B. Yu, Rex R. Malmstrom, Jeffrey Blanchard, Tanja Woyke   +7 more
doaj   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

Discovery and Further Studies on Giant Viruses at the IHU Mediterranee Infection That Modified the Perception of the Virosphere

Viruses, 2019
The history of giant viruses began in 2003 with the identification of Acanthamoeba polyphaga mimivirus. Since then, giant viruses of amoeba enlightened an unknown part of the viral world, and every discovery and characterization of a new giant virus ...
Clara Rolland, Julien Andreani, Amina Cherif Louazani, Sarah Aherfi, Rania Francis, Rodrigo Rodrigues, Ludmila Santos Silva, Dehia Sahmi, Said Mougari, Nisrine Chelkha, Meriem Bekliz, Lorena Silva, Felipe Assis, Fábio Dornas, Jacques Yaacoub Bou Khalil, Isabelle Pagnier, Christelle Desnues, Anthony Levasseur, Philippe Colson, Jônatas Abrahão, Bernard La Scola   +20 more
doaj   +1 more source

Human papilloma virus-16 causing giant condyloma acuminata [PDF]

Journal of Surgical Case Reports, 2014
A 28-year-old multiparous lady presented to the Gynaecology outpatient department with a 12 × 5 cm warty growth in the vulva. A biopsy of the growth revealed condyloma acuminata of the vulva. Simple vulvectomy was done. A PCR of the specimen detected the presence of human papilloma virus (HPV)-16 which is usually considered as a high-risk HPV type for ...
Bhageerathy, Pallipuram Seshadrinathan, Cecilia, Maria, Sebastian, Ajit, Raghavendran, Anantharam, Abraham, Priya, Thomas, Anitha, Peedicayil, Abraham   +6 more
openaire   +2 more sources

Faustovirus-like asfarvirus in hematophagous biting midges and their vertebrate hosts.

Frontiers in Microbiology, 2015
Faustovirus, a new Asfarviridae-related giant virus, was recently isolated in Vermamoeba vermiformis, a protist found in sewage water in various geographical locations and occasionally reported in human eye infection cases.
Sarah eTemmam, Sonia eMonteil-Bouchard, Masse eSambou, Maxence eAubadie-Ladrix, Saïd eAzza, Philippe eDecloquement, Jacques Yaacoub Bou Khalil, Jean-Pierre eBaudoin, Priscilla eJardot, Catherine eRobert, Bernard eLa Scola, Oleg Y. Mediannikov, Didier eRaoult, Christelle eDesnues   +13 more
doaj   +1 more source