Results 51 to 60 of about 3,291 (136)

Gingipains como factores de virulência na cavidade oral [PDF]

, 2009
Mestrado em MicrobiologiaPorphyromonas gingivalis, uma bactéria anaeróbia Gram negativa, é um importante agente etiológico da doença periodontal, sendo encontrada em bolsas periodontais que apresentam doença activa. A actividade proteolítica desencadeada
Lopes, Pedro André Ferreira Campos
core  

Gingipains as candidate antigens for Porphyromonas gingivalis vaccine [PDF]

, 2020
. Porphyromonas gingivalis (P. gingivalis), a gram-negative anaerobe, is involved in the pathogenesis of periodontal disease, and is found frequently in the subgingival flora in patients with periodontitis.
Yasuo Hosaka, Kazuyuki Ishihara2, Taneaki Nakagawa, Atsushi Saito1   +3 more
core  

Molecular mechanisms of Porphyromonas gingivalis-host cell interaction on periodontal diseases

Japanese Dental Science Review, 2017
Porphyromonas gingivalis (P. gingivalis) is a major oral pathogen and associated with periodontal diseases including periodontitis and alveolar bone loss. In this review, we indicate that two virulence factors, which are hemoglobin receptor protein (HbR)
Masaaki Nakayama, Naoya Ohara
doaj   +1 more source

Alzheimer’s Disease and Porphyromonas gingivalis: Exploring the Links

Life
Recent research highlights compelling links between oral health, particularly periodontitis, and systemic diseases, including Alzheimer’s disease (AD).
Ivana Shawkatova, Vladimira Durmanova, Juraj Javor   +2 more
doaj   +1 more source

Taurolidine Acts on Bacterial Virulence Factors and Does Not Induce Resistance in Periodontitis-Associated Bacteria—An In-Vitro Study

Antibiotics, 2020
The aims of the present study were: (a) to determine the mechanism of action of taurolidine against bacterial species associated with periodontal disease, and (b) to evaluate the potential development of resistance against taurolidine as compared with ...
Sabrina Radakovic, Nicola Andreoli, Simon Schmid, Sandor Nietzsche, Jürg Zumbrunn, Anton Sculean, Sigrun Eick   +6 more
doaj   +1 more source

Isolation, characterization, and fibroblast uptake of bacterial extracellular vesicles from Porphyromonas gingivalis strains

MicrobiologyOpen, 2023
Periodontitis is an inflammatory condition caused by bacteria and represents a serious health problem worldwide as the inflammation damages the supporting tissues of the teeth and may predispose to systemic diseases.
Helene R. Haugsten, Anne K. Kristoffersen, Trude M. Haug, Tine M. Søland, Reidun Øvstebø, Hans C. D. Aass, Morten Enersen, Hilde K. Galtung   +7 more
doaj   +1 more source

Gingipains as a virulence factor in the oral cavity [PDF]

, 2012
AimThe objective of this study is to demonstrate the molecular action of Porphyromonas gingivalis cysteine proteases such as gingipains (R1, R2 and K) upon human molecules.Materials and methodsUsing the information on protein structure and function ...
Campos Lopes, Pedro, Barros, Marlene, Lopes, Pedro Campos, Correia, Maria José   +3 more
core   +1 more source

Porphyromonas gingivalis regulates TREM-1 in human polymorphonuclear neutrophils via its gingipains. [PDF]

PLoS ONE, 2013
The Triggering Receptor Expressed on Myeloid cells 1 (TREM-1) is a cell surface receptor of the immunoglobulin superfamily, with the capacity to amplify pro-inflammatory cytokine production and regulate apoptosis. Polymorphonuclear neutrophils (PMNs) are
Nagihan Bostanci, Thomas Thurnheer, Joseph Aduse-Opoku, Michael A Curtis, Annelies S Zinkernagel, Georgios N Belibasakis   +5 more
doaj   +1 more source

Supplementary Material for: Gingipains: Critical Factors in the Development of Aspiration Pneumonia Caused by Porphyromonas gingivalis

, 2016
Aspiration pneumonia is a life-threatening infectious disease often caused by oral anaerobic and periodontal pathogens such as Porphyromonas gingivalis.
Płaza K. (3230265), Milewska A. (3230283), Benedyk M. (3230286), Delaleu N. (3230268), Potempa J. (2935359), Pyrc K. (3230274), Gawron K. (3230271), Maresz K. (3230280), Koziel J. (2935365), Mydel P.M. (3230277)   +9 more
core   +1 more source

Inhibition of gingipains by their profragments as the mechanism protecting Porphyromonas gingivalis against premature activation of secreted proteases [PDF]

, 2013
et al.[Background]: Arginine-specific (RgpB and RgpA) and lysine-specific (Kgp) gingipains are secretory cysteine proteinases of Porphyromonas gingivalis that act as important virulence factors for the organism.
Potempa, Jan, Enghild, Jan J., Gomis-Rüth, F. Xavier, Veillard, Florian T.   +3 more
core   +1 more source