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Angiomodulatory and Neurological Effects of Ginsenosides

Current Medicinal Chemistry, 2007
Panax ginseng C.A. Meyer, one of the most popular and valued herbs, has been used extensively in traditional Chinese medicine for thousands of years. More than thirty ginsenosides, the pharmacologically active ingredients in ginseng, have been identified with various sugar moieties attached at the C-3, C-6 and C-20 positions of the steroidal skeleton ...
Ng, TB   +9 more
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Analysis methods of ginsenosides

Journal of Chromatography B, 2004
Ginsenosides are considered the main active principles of the famous Chinese traditional medicine "ginseng". For more than 30 years many researchers developed methods for the identification and quantification of ginsenosides in ginseng plant material, extracts and products.
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Ginseng Omics for Ginsenoside Biosynthesis

Current Pharmaceutical Biotechnology, 2021
Ginseng, also known as the king of herbs, has been regarded as an important traditional medicine for several millennia. Ginsenosides, a group of triterpenoid saponins, have been characterized as bioactive compounds of ginseng. The complexity of ginsenosides hindered ginseng research and development both in cultivation and clinical research. Therefore,
Xianmei Yin   +5 more
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Ginsenosides, potent inhibitors of sialyltransferase

Zeitschrift für Naturforschung C, 2020
Abstract The overexpression of sialic acids and sialyltransferases (STs) during malignant transformation and progression could result in the aberrant sialylation of cancer cells. Therefore, interfering the sialic acid synthesis might be an effective pathway in cancer therapy. In this study, we assessed that the antitumor inhibitors of 20(
Wenxin, Huang   +6 more
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Antiphotoaging and Antimelanogenesis Properties of Ginsenoside C‐Y, a Ginsenoside Rb2 Metabolite from American Ginseng PDD‐ginsenoside

Photochemistry and Photobiology, 2019
AbstractGinsenosides are compounds responsible for the primary pharmacological effects of American ginseng. Compound‐Y (C‐Y) is a minor ginsenoside and a metabolite of Panax ginseng. In this study, we investigated the protective effect of ginsenoside UVB‐irradiated NHDFs and its potential for use as an antihyperpigmentation agent through ginsenoside C ...
Xiao‐yi Liu   +4 more
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Characterization of the ginsenoside-transforming recombinant β-glucosidase from Actinosynnema mirum and bioconversion of major ginsenosides into minor ginsenosides

Applied Microbiology and Biotechnology, 2012
This study focused on the cloning, expression, and characterization of ginsenoside-transforming recombinant β-glucosidase from Actinosynnema mirum KACC 20028(T) in order to biotransform ginsenosides efficiently. The gene, termed as bglAm, encoding a β-glucosidase (BglAm) belonging to the glycoside hydrolase family 3 was cloned. bglAm consisted of 1,830
Cui, CH Cui, Chang-Hao   +2 more
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Biotransformation of ginsenosides by hydrolyzing the sugar moieties of ginsenosides using microbial glycosidases

Applied Microbiology and Biotechnology, 2010
Ginsenosides are the principal components responsible for the pharmaceutical activities of ginseng. The minor ginsenosides, which are also pharmaceutically active, can be produced via the hydrolysis of the sugar moieties in the major ginsenosides using acid hydrolytic, heating, microbial, and enzymatic transformation techniques.
Chang-Su, Park   +3 more
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Biosynthesis and biotechnological production of ginsenosides

Biotechnology Advances, 2015
Medicinal plants are essential for improving human health, and around 75% of the population in developing countries relies mainly on herb-based medicines for health care. As the king of herb plants, ginseng has been used for nearly 5,000 years in the oriental and recently in western medicines. Among the compounds studied in ginseng plants, ginsenosides
Kim, Y., Zhang, D., Yang, D.
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Synthesis of Ocotillol-Type Ginsenosides

The Journal of Organic Chemistry, 2016
A total of 14 ocotillol-type ginsenosides were conveniently synthesized employing glycosylation of ocotillol sapogenin derivatives with glucosyl ortho-alkynylbenzoate donors under the promotion of a gold(I) catalyst as the key step. Relying on a rational protecting group strategy and the unexpected regioselectivity of the glycosylation of the 3,25-diol
Renzeng, Shen   +4 more
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Anti-Angiogenic Properties of Ginsenoside Rg3

Molecules, 2020
Maryam Nakhjavani   +2 more
exaly  

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