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Characterization of the ginsenoside-transforming recombinant β-glucosidase from Actinosynnema mirum and bioconversion of major ginsenosides into minor ginsenosides

Applied Microbiology and Biotechnology, 2012
This study focused on the cloning, expression, and characterization of ginsenoside-transforming recombinant β-glucosidase from Actinosynnema mirum KACC 20028(T) in order to biotransform ginsenosides efficiently. The gene, termed as bglAm, encoding a β-glucosidase (BglAm) belonging to the glycoside hydrolase family 3 was cloned. bglAm consisted of 1,830
Cui, CH Cui, Chang-Hao   +2 more
openaire   +3 more sources

Biotransformation of ginsenosides by hydrolyzing the sugar moieties of ginsenosides using microbial glycosidases

Applied Microbiology and Biotechnology, 2010
Ginsenosides are the principal components responsible for the pharmaceutical activities of ginseng. The minor ginsenosides, which are also pharmaceutically active, can be produced via the hydrolysis of the sugar moieties in the major ginsenosides using acid hydrolytic, heating, microbial, and enzymatic transformation techniques.
Chang-Su, Park   +3 more
openaire   +2 more sources

Biosynthesis and biotechnological production of ginsenosides

Biotechnology Advances, 2015
Medicinal plants are essential for improving human health, and around 75% of the population in developing countries relies mainly on herb-based medicines for health care. As the king of herb plants, ginseng has been used for nearly 5,000 years in the oriental and recently in western medicines. Among the compounds studied in ginseng plants, ginsenosides
Kim, Y., Zhang, D., Yang, D.
openaire   +3 more sources

Synthesis of Ocotillol-Type Ginsenosides

The Journal of Organic Chemistry, 2016
A total of 14 ocotillol-type ginsenosides were conveniently synthesized employing glycosylation of ocotillol sapogenin derivatives with glucosyl ortho-alkynylbenzoate donors under the promotion of a gold(I) catalyst as the key step. Relying on a rational protecting group strategy and the unexpected regioselectivity of the glycosylation of the 3,25-diol
Renzeng, Shen   +4 more
openaire   +2 more sources

Anti-Angiogenic Properties of Ginsenoside Rg3

Molecules, 2020
Maryam Nakhjavani   +2 more
exaly  

Ginsenoside Rg3

2018
Zhen-Zhen Wang   +2 more
openaire   +1 more source

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