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Conversion of Major Ginsenoside Rb1 to Ginsenoside F2 by Caulobacter leidyia

Biotechnology Letters, 2006
Ginsenoside Rb1 is the most predominant ginsenoside in Panax species (ginseng) and the hydrolysis of this ginsenoside produces pharmaceutically active compounds. Caulobacter leidyia GP45, one of the isolates having strong beta-glucosidase-producing activity, converted ginsenoside Rb(1) to the active metabolites by 91%.
Le-Qin, Cheng   +4 more
openaire   +4 more sources

Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514

Phytochemistry, 2008
Ginseng saponin, the most important secondary metabolite in ginseng, has various pharmacological activities. Many studies have been directed towards converting major ginsenosides to the more active minor ginsenoside, Rg3. Due to the difficulty in preparing ginsenoside Rg3 enzymatically, the compound has been mainly produced by either acid treatment or ...
Le-Qin, Cheng   +4 more
openaire   +4 more sources

Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis

Anti-Cancer Agents in Medicinal Chemistry, 2023
Background: Colorectal cancer (CRC) is the third most common cancer worldwide. Current treatments, including surgery, radiotherapy, and chemotherapy, are limited by severe side effects and the development of resistance. Objective: Therefore, it is important to find additional therapies to combat the problem.
Ling, Wang   +8 more
openaire   +2 more sources

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