Integration of 16S rRNA sequencing and metabolomics to investigate the modulatory effect of ginsenoside Rb1 on atherosclerosis. [PDF]
Liang Y +5 more
europepmc +1 more source
Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB. [PDF]
Zhou Y +8 more
europepmc +1 more source
Ginsenoside Rb1 prevents age-related endothelial senescence by modulating SIRT1/caveolin-1/enos signaling pathway. [PDF]
Zhou B +9 more
europepmc +1 more source
Ginsenoside Rb<sub>1</sub> Ameliorates Heart Failure Ventricular Remodeling by Regulating the Twist1/PGC-1α/PPARα Signaling Pathway. [PDF]
Zhou Z +6 more
europepmc +1 more source
Methanol-involved heterogeneous transformation of ginsenoside Rb1 to rare ginsenosides using heteropolyacids embedded in mesoporous silica with HPLC-MS investigation. [PDF]
Zhao M +7 more
europepmc +1 more source
Ginsenoside Rb1 induces hepatic stellate cell ferroptosis to alleviate liver fibrosis via the BECN1/SLC7A11 axis. [PDF]
Lin L +5 more
europepmc +1 more source
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Conversion of Major Ginsenoside Rb1 to Ginsenoside F2 by Caulobacter leidyia
Biotechnology Letters, 2006Ginsenoside Rb1 is the most predominant ginsenoside in Panax species (ginseng) and the hydrolysis of this ginsenoside produces pharmaceutically active compounds. Caulobacter leidyia GP45, one of the isolates having strong beta-glucosidase-producing activity, converted ginsenoside Rb(1) to the active metabolites by 91%.
Le-Qin, Cheng +4 more
openaire +4 more sources
Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514
Phytochemistry, 2008Ginseng saponin, the most important secondary metabolite in ginseng, has various pharmacological activities. Many studies have been directed towards converting major ginsenosides to the more active minor ginsenoside, Rg3. Due to the difficulty in preparing ginsenoside Rg3 enzymatically, the compound has been mainly produced by either acid treatment or ...
Le-Qin, Cheng +4 more
openaire +4 more sources
Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis
Anti-Cancer Agents in Medicinal Chemistry, 2023Background: Colorectal cancer (CRC) is the third most common cancer worldwide. Current treatments, including surgery, radiotherapy, and chemotherapy, are limited by severe side effects and the development of resistance. Objective: Therefore, it is important to find additional therapies to combat the problem.
Ling, Wang +8 more
openaire +2 more sources

