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High efficiency production of ginsenoside compound K by catalyzing ginsenoside Rb1 using snailase
Chinese Journal of Chemical Engineering, 2018Abstract The rare ginsenoside Compound K (C-K) is attracting more attention because of its good physiological activity and urgent need. There are many pathways to obtain ginsenoside C-K, including chemical and biological methods. Among these, the conversion of PPD-type ginsenosides by enzymatic hydrolysis is a trend due to its high efficiency and ...
Zhiguang Duan +7 more
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Bioresource Technology, 2010
Paecilomyces bainier 229-7 was obtained after UV irradiation for 8 min in the presence of 0.4% LiCl and selection on potato dextrose media containing 30 mg/mL saponin from Panax notoginseng leaves (SPNL). The mutant produces ginsenoside Rd from ginsenoside Rb1 with a bioconversion rate as high as 94.9% under optimized culture conditions in shake flasks
Li, Ye +7 more
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Paecilomyces bainier 229-7 was obtained after UV irradiation for 8 min in the presence of 0.4% LiCl and selection on potato dextrose media containing 30 mg/mL saponin from Panax notoginseng leaves (SPNL). The mutant produces ginsenoside Rd from ginsenoside Rb1 with a bioconversion rate as high as 94.9% under optimized culture conditions in shake flasks
Li, Ye +7 more
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[Immunodetection of ginsenoside Rb1 in rat serum].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010To establish a novel immunoassay for qualitative detection of ginsenoside Rb1 in rat serum.Anti-G-Rb1 monoclonal antibody (mAb) was through a hybridoma approach. Rat serum containing G-Rb1 was deproteinized with methanol to prepare the sample for testing, which was loaded onto polyethersulfone (PES) membrane and developed in the mixture of acetonitrile,
Li-ling, Ma +3 more
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Effects of Ginsenoside Rb1 on Skin Changes
2012Ginseng roots (Panax ginseng CA Meyer) have been used traditionally for the treatment, especially prevention, of various diseases in China, Korea, and Japan. Both experimental and clinical studies suggest ginseng roots to have pharmacological effects in patients with life-style-related diseases such as non-insulin-dependent diabetic mellitus ...
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Effects of ginsenoside Rb1 on central cholinergic metabolism.
Pharmacology, 1991Ginsenosides, the saponins of ginseng, are bioactive ingredients which exert many beneficial effects. One ginsenoside, Rb1, extracted from North American ginseng (Panax quinquefolium L.), partially prevents the memory deficits induced by a cholinergic agent (scopolamine) in rats.
C G, Benishin +3 more
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[Purification of a ginsenoside-Rb1 hydrolase from Helix snailase].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2009Through a combination of twice DEAE chromatography by NaCl stepwise and gradient elution with gel filtration chromatography, a kind of ginsenoside-Rb1 hydrolase from crude Helix snailase was separated. The hydrolase was purified to apparent homogeneity on SDS-PAGE.
Xin, Liu +3 more
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