Results 31 to 40 of about 7,976 (200)

Neuroprotective Effects of Ginsenoside-Rg1 Against Depression-Like Behaviors via Suppressing Glial Activation, Synaptic Deficits, and Neuronal Apoptosis in Rats

open access: yesFrontiers in Immunology, 2018
Depression is considered a neuropsychiatric disease associated with various neuronal changes within specific brain regions. We previously reported that ginsenoside-Rg1, a potential neuroprotective agent extracted from ginseng, significantly alleviated ...
Cuiqin Fan   +6 more
doaj   +1 more source

Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion [PDF]

open access: yes, 2011
Background: Panax notoginseng is commonly used for the treatment of cardiovascular diseases in China. The present study investigates the effects of three different saponin fractions (ie total saponins, PNS; protopanaxadiol-type saponin, PDS; and ...
Nan Wang   +7 more
core   +2 more sources

Ginsenoside Rg1 as a Potential Regulator of Hematopoietic Stem/Progenitor Cells [PDF]

open access: yesStem Cells International, 2021
Ginsenoside Rg1 (Rg1), a purified, active component of the root or stem of ginseng, exerts positive effects on mesenchymal stem cells (MSCs). Many recent studies have found that hematopoietic stem cells (HSCs), which can develop into hematopoietic progenitor cells (HPCs) and mature blood cells, are another class of heterogeneous adult stem cells that ...
Fang He, Guanping Yao
openaire   +3 more sources

Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis

open access: yesMolecular Medicine Reports, 2013
Lidocaine, as an anesthetic substance, is often used for surface and spinal anesthesia. However, studies have shown that lidocaine may induce transient neurological symptoms and cauda equina syndrome. In the present study the effects of the ginsenoside Rg1 (Rg1) on lidocaine‑induced apoptosis were assessed in Jurkat cells using flow cytometry and ...
LI, HUI   +3 more
openaire   +3 more sources

Neuroprotective effects of ginsenoside Rg1-induced neural stem cell transplantation on hypoxic-ischemic encephalopathy

open access: yesNeural Regeneration Research, 2015
Ginsenoside Rg1 is the major pharmacologically active component of ginseng, and is reported to have various therapeutic actions. To determine whether it induces the differentiation of neural stem cells, and whether neural stem cell transplantation after ...
Ying-bo Li   +4 more
doaj   +1 more source

Ginsenoside Rg1 in Parkinson's disease: from basic research to clinical applications. [PDF]

open access: yesFront Pharmacol
This review provides an in-depth exploration of the potential of Ginsenoside Rg1 in the treatment of Parkinson’s disease (PD). The emphasis of this article was the therapeutic mechanisms of Rg1, which involved the reduction of inflammation, antioxidant properties, support for neuronal survival and regeneration, regulation of cellular energy processes ...
Wang Q, Wei L, Chen G, Chen Q.
europepmc   +4 more sources

Plants-derived neuroprotective agents: Cutting the cycle of cell death through multiple mechanisms [PDF]

open access: yes, 2017
Neuroprotection is the preservation of the structure and function of neurons from insults arising from cellular injuries induced by a variety of agents or neurodegenerative diseases (NDs).
Berida, Tomayo Ireti   +2 more
core   +3 more sources

Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1

open access: yesJournal of Ginseng Research, 2023
Rara vez se informan los efectos del ginsenósido principal Rg1 en la longevidad y la vitalidad física de los mamíferos. Para examinar la longevidad, el tumor y la actividad locomotora espontánea en ratas que consumen Rg1. Un total de 138 ratas Wistar se asignaron al azar en 2 grupos: control (N = 69) y Rg1 (N = 69).
Chao-Chieh Hsieh   +8 more
openaire   +3 more sources

A systematic review and meta-analysis of Ginsenoside-Rg1 (G-Rg1) in experimental ischemic stroke [PDF]

open access: yesScientific Reports, 2015
The neuroprotective actions of Ginsenoside-Rg1 (G-Rg1) have been documented for experimental stroke therapy. We used a systematic review and meta-analysis to assess the efficacy of G-Rg1 in experimental ischemic stroke. We identified studies describing the efficacy of G-Rg1 in animal models of focal cerebral ischemia.
Xie, Cheng-long   +5 more
openaire   +2 more sources

Ginsenoside Rg1 Nanoparticles Induce Demethylation of H3K27me3 in VEGF-A and Jagged 1 Promoter Regions to Activate Angiogenesis After Ischemic Stroke

open access: yesInternational Journal of Nanomedicine, 2022
Wei Shang, Xin Zhao, Fan Yang, Dongyi Wang, Le Lu, Zihan Xu, Zhiming zhao, Hui Cai, Junyi Shen Department of Integrated Traditional and Western Medicine, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, People’s Republic of ...
Shang W   +8 more
doaj  

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