Results 31 to 40 of about 9,296 (235)

Antioxidant and anti-inflammatory properties of ginsenoside Rg1 for hyperglycemia in type 2 diabetes mellitus: systematic reviews and meta-analyses of animal studies

open access: yesFrontiers in Pharmacology, 2023
Background: According to existing laboratory data, ginsenoside Rg1 may help cure diabetes and its complications by reducing oxidative stress (OS) and managing inflammation. However, this conclusion lacks reliability and is unclear.
Qian Xie   +7 more
doaj   +1 more source

Ginsenoside Rg1 attenuates liver injury induced by D‑galactose in mice

open access: diamondExperimental and Therapeutic Medicine, 2018
The present study investigated the effect and underlying mechanisms of ginsenoside Rg1 (Rg1) in attenuating subacute liver injury induced by D-galactose (D-gal) in mice. Specific Pathogen Free (SPF) male C57BL/6J mice were randomly divided into 3 groups: i) D-gal-administration group (D-gal group), where the mice were intraperitoneally administrated ...
Minghe Xiao   +9 more
openalex   +5 more sources

Protective effect of ginsenoside Rg1 on attenuating anti-GBM glomerular nephritis by activating NRF2 signalling

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Background/Aim Ginsenoside Rg1 exerts a beneficial effect in many kidney diseases. But little work has been done to confirm whether ginsenoside Rg1 could also exert a protective effect on anti-glomerular basement membrane (anti-GBM) glomerular nephritis (
Xiaojuan Guo   +3 more
doaj   +1 more source

Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging. [PDF]

open access: yesPLoS ONE, 2014
Neurogenesis continues throughout the lifetime in the hippocampus, while the rate declines with brain aging. It has been hypothesized that reduced neurogenesis may contribute to age-related cognitive impairment. Ginsenoside Rg1 is an active ingredient of
Jiahong Zhu   +9 more
doaj   +1 more source

Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. [PDF]

open access: yes, 2007
In Chinese medicine, ginseng (Panax ginseng C.A. Meyer) has long been used as a general tonic or an adaptogen to promote longevity and enhance bodily functions.
Cheng, Yuen Kit   +7 more
core   +1 more source

Immunomodulating Activity of Ginsenoside Rg1 from Panax Ginseng

open access: yesJapanese Journal of Pharmacology, 1990
The immunomodulatory activity of ginsenoside Rg1 from Panax ginseng was studied in mice using sheep red cells as the antigen. It was found that ginsenoside Rg1 at a dose of 10 mg/kg administered for three consecutive days before immunization increased the number of spleen plaque-forming cell, the titers of sera hemagglutinins as well as the number of ...
B, Kenarova   +3 more
openaire   +3 more sources

Selected ginsenosides of the prptopanaxdiol series are novel positive allosteric modulators of P2X7 receptors [PDF]

open access: yes, 2015
Background and Purpose The P2X7 receptor is an ATP-gated ion channel predominantly expressed in immune cells and plays a key role in inflammatory processes.
Adinolfi   +48 more
core   +1 more source

Effects of Dietary Ginsenoside Rg1 Supplementation on Growth Performance, Gut Health, and Serum Immunity in Broiler Chickens

open access: yesFrontiers in Nutrition, 2021
The restriction and banning of antibiotics in farm animal feed has led to a search for promising substitutes for antibiotics to promote growth and maintain health for livestock and poultry.
Zehe Song   +14 more
doaj   +1 more source

Ginsenoside Rg1 Protects Cardiomyocytes Against Hypoxia/Reoxygenation Injury via Activation of Nrf2/HO-1 Signaling and Inhibition of JNK

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: Excessive reactive oxygen species (ROS) disturb the physiology of H9c2 cells, which is regarded as a major cause of H9c2 cardiomyocyte apoptosis.
Qianhui Li   +4 more
doaj   +1 more source

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