Results 141 to 150 of about 3,001 (186)
Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer. [PDF]
Mol MedLiu X, Li J, Huang Q, Jin M, Huang G.
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Ginsenoside Rh2 Alleviates LPS-Induced Inflammatory Responses by Binding to TLR4/MD-2 and Blocking TLR4 Dimerization. [PDF]
Int J Mol SciPan S +6 more
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Ginsenoside Rh2: A Potential Therapeutic Strategy for Liver Cancer
Advances in Clinical Medicineopenaire +1 more source
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Anticancer Effects of Ginsenoside Rh2: A Systematic Review
Current Molecular Pharmacology, 2021Background: As one of the effective pharmacological constituents of Ginseng Radix et Rhizoma, ginsenoside Rh2 (Rh2) exerts a remarkable anticancer effect on various cancer cell lines in vitro and strongly inhibits tumor growth in vivo without severe toxicity. Objective: This article reviewed existing evidence supporting the anticancer effects of Rh2
Jinjian Lu, Yitao Wang, Xiuping Chen
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Antiallergic Activity of Ginsenoside Rh2
Biological and Pharmaceutical Bulletin, 2003 The antiallergic activities of ginsenosides, which were isolated from acid-treated ginseng (Panax ginseng, Araliaceae), and their metabolites by human intestinal bacteria were measured. Ginsenoside Rh2, which is a main metabolite, had the most potent inhibitory activity on beta-hexosaminidase release from RBL-2H3 cells and in the passive cutaneous ...
Myung Joo Han +2 more
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Anticancer property of ginsenoside Rh2 from ginseng
European Journal of Medicinal Chemistry, 2020Ginseng has been used as a well-known traditional Chinese medicine since ancient times. Ginsenosides as its main active constituents possess a broad scope of pharmacological properties including stimulating immune function, enhancing cardiovascular health, increasing resistance to stress, improving memory and learning, developing social functioning and
Nai-Hong Chen, Xun Li, Yingjiao Liu
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Journal of Pharmaceutical Sciences, 1991
The uptake and metabolism of ginsenoside Rh2 (Rh2) by B16 melanoma cells were studied. In a medium containing 2% fetal calf serum, the uptake of Rh2 reached a maximum of 3 nmol/10(6) cells at 3-6 h after Rh2 (12.5 microM) was added, but gradually decreased to 0.8 nmol/10(6) cells.
T, Ota, M, Maeda, S, Odashima
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The uptake and metabolism of ginsenoside Rh2 (Rh2) by B16 melanoma cells were studied. In a medium containing 2% fetal calf serum, the uptake of Rh2 reached a maximum of 3 nmol/10(6) cells at 3-6 h after Rh2 (12.5 microM) was added, but gradually decreased to 0.8 nmol/10(6) cells.
T, Ota, M, Maeda, S, Odashima
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Treatment of Stress Urinary Incontinence by Ginsenoside Rh2
The American Journal of Chinese Medicine, 2014Stress urinary incontinence (SUI) is a common disorder in middle-aged women and the elderly. Although surgical treatment of SUI has progressed, there are no effective pharmacological therapies without a side effect. We studied the effect of ginsenoside Rh2 against SUI.
Yung-Hsiang, Chen +4 more
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Preparation and bioactivity of the rare ginsenosides Rg3 and Rh2: An updated review
Fitoterapia, 2023Ginseng, an ancient medicinal herb, is used in oriental medicine for the treatment of various diseases. Saponins are the main bioactive components of ginseng, but the multiple glucosyl side chains on its molecules prevent ginsenosides from entering the blood through the intestinal membrane, thus reducing the efficacy.
Wenqi, Xu +5 more
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Advances in Ginsenoside Rh2 and Its Derivatives
World Science and Technology, 2012Abstract Ginsenoside Rh2, one of the characteristic components in red ginseng (roots steamed at 98-100 °C without peeling), is a rare ginsenoside with potential bioactivity. The preparation of ginsenoside Rh2 was studied by using acid hydrolysis, alkaline hydrolysis, synthesis and biotransformation techniques.
Man Cao +4 more
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