Results 51 to 60 of about 631 (158)
Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022 Aging is associated with the occurrence of diverse degenerative changes in various tissues and organs and with an increased incidence of neurological disorders, especially neurodegenerative diseases such as Alzheimer’s disease (AD). In recent years, the search for effective components derived from medicinal plants in delaying aging and preventing and ...
Qin Li +7 more
wiley +1 more source
Journal of Ginseng Research, 2021 Background: In ginseng, there exists a glycolipoprotein complex with a special form of lipid LPAs called Gintonin. The purpose of this study is to show that Gintonin has a therapeutic effect on rheumatoid arthritis through LPA2 receptors.
Mijin Kim +5 more
doaj +1 more source
Journal of Ginseng Research, 2021 Background: We recently showed that gintonin, an active ginseng ingredient, exhibits antibrain neurodegenerative disease effects including multiple target mechanisms such as antioxidative stress and antiinflammation via the lysophosphatidic acid (LPA ...
Sung Min Nam +9 more
doaj +1 more source
Ginseng in Hair Growth and Viability [PDF]
, 2021 The hair follicle is the unique organ that has the capacity of undergoing cyclic transformations following periods of growth (anagen), regression (catagen), and rest (telogen) regenerating itself to restart the cycle.
Dionisio L., Lorenzo-Villegas +4 more
core +2 more sources
A review on phyto-nanotechnology for therapy of alzheimer’s disease [PDF]
, 2022 Alzheimer’s disease (AD) is a common chronic neurodegenerative disease (ND) that is mainly investigated nowadays because of its increased incidence and burden on the elderly population. It leads to atrophy of the brain.
R, Gayathri, SL, Manju
core +2 more sources
Yin and Yang of ginseng pharmacology: ginsenosides vs gintonin [PDF]
Acta Pharmacologica Sinica, 2013 Ginseng, the root of Panax ginseng, has been used in traditional Chinese medicine as a tonic herb that provides many beneficial effects. Pharmacologic studies in the last decades have shown that ginsenosides (ginseng saponins) are primarily responsible for the actions of ginseng.
Im, Dong-soon, Nah, Seung-yeol
openaire +2 more sources
To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors? [PDF]
, 2020 The family of ligand-gated ion channels known as P2X receptors were discovered several decades ago. Since the cloning of the seven P2X receptors (P2X1-P2X7), a huge research effort has elucidated their roles in regulating a range of physiological and ...
Allum, Elizabeth +3 more
core +1 more source
Effects of Gintonin-Enriched Fraction on Methylmercury-Induced Neurotoxicity and Organ Methylmercury Elimination [PDF]
International Journal of Environmental Research and Public Health, 2020 Gintonin is a newly discovered ingredient of ginseng and plays an exogenous ligand for G protein-coupled lysophosphatidic acid receptors. We previously showed that gintonin exhibits diverse effects from neurotransmitter release to improvement of Alzheimer’s disease-related cognitive dysfunctions.
Hyeon-Joong Kim +7 more
openaire +2 more sources
Nrf2 as a Potential Therapeutic Target for Treatment of Huntington’s Disease [PDF]
, 2022 Oxidative stress-induced neuronal damage plays a significant role in pathogenesis of several neuro-degenerative disorders including Huntington’s disease.
Jayaram, Saravanan +3 more
core +2 more sources
Ginsenosides act as positive modulators of P2X4 receptors [PDF]
, 2018 We investigated the selectivity of protopanaxadiol ginsenosides from Panax ginseng acting as positive allosteric modulators on P2X receptors. ATP-induced responses were measured in stable cell lines overexpressing human P2X4 using a YOPRO-1 dye uptake ...
Asatryan +23 more
core +3 more sources