Results 91 to 100 of about 74,465 (332)

GIP as a Potential Therapeutic Target for Atherosclerotic Cardiovascular Disease–A Systematic Review

International Journal of Molecular Sciences, 2020
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are gut hormones that are secreted from enteroendocrine L cells and K cells in response to digested nutrients, respectively.
Y. Mori, T. Matsui, T. Hirano, S. Yamagishi   +3 more
semanticscholar   +1 more source

The Real Effect of Banking Globalisation on Bank Liquidity Creation in China's Banking Sector: Evidence From the Belt and Road Initiative

International Studies of Economics, EarlyView.
ABSTRACT To explore the real effect of banking globalisation on bank liquidity creation, we investigate plausibly exogenous variations in the expectation of further banking globalisation under the Belt and Road Initiative (BRI), which further opens the gate to foreign investors.
Xuanyi Shi, Wenjun Wu, Yifan Chen, Chunyang Wang   +3 more
wiley   +1 more source

Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation. [PDF]

PLoS ONE, 2013
Gastric inhibitory polypeptide (GIP) is a gut derived peptide with multiple emerging physiological actions. Effects of pregnancy and lactation on GIP secretion and related gene expression were studied in Wistar rats.
R Charlotte Moffett, Nigel Irwin, Jacqueline M E Francis, Peter R Flatt   +3 more
doaj   +1 more source

"Two tribes": Handaxe shape variation shows distinct regional cultural groups in southeastern Britain between 424 000 and 374 000 BP

Journal of Quaternary Science, EarlyView.
ABSTRACT This paper examines regional and chronological variations in Acheulean handaxe morphology during Marine Isotope Stage 11 (c. 425–365 ka BP) in Britain. Using a data set of 737 handaxes from 13 securely dated sites in East Anglia and the Thames Valley, we apply three‐dimensional geometric morphometric analysis to examine morphological ...
Mark White, Frederick Foulds, Aaron Rawlinson, Ceri Shipton, Rob Davis, Nick Ashton   +5 more
wiley   +1 more source

Tirzepatide, GIP(1-42) and GIP(1-30) display unique signaling profiles at two common GIP receptor variants, E354 and Q354

Frontiers in Pharmacology
Type 2 diabetes (T2D) and obesity are prevalent metabolic disorders affecting millions of individuals worldwide. A new effective therapeutic drug called tirzepatide for the treatment of obesity and T2D is a dual agonist of the GIP receptor and GLP-1 ...
Tayla A. Rees, Tayla A. Rees, Tayla A. Rees, Benjamin J. Buttle, Zoe Tasma, Zoe Tasma, Sung-Hyun Yang, Paul W. R. Harris, Paul W. R. Harris, Paul W. R. Harris, Christopher S. Walker, Christopher S. Walker   +11 more
doaj   +1 more source

Effects of High Glucose Levels and Glycated Serum on GIP Responsiveness in the Pancreatic Beta Cell Line HIT-T15

Journal of Diabetes Research, 2015
Glucose-dependent insulinotropic peptide (GIP) is an incretin hormone produced in the gastrointestinal tract that stimulates glucose dependent insulin secretion.
Alessandra Puddu, Roberta Sanguineti, Fabrizio Montecucco, Giorgio Luciano Viviani   +3 more
doaj   +1 more source

PANCREATIC AND EXTRA-PANCREATIC EFFECTS OF INCRETINS AND PERSPECTIVES FOR STUDYING ENTEROINSULIN HORMONAL SYSTEM DURING GESTATIONAL DISORDER OF CARBOHYDRATE METABOLISM

Бюллетень сибирской медицины, 2013
The absence of an ideal medicine for the treatment of patients with type 2 diabetes, that would be able to provide not only high quality and constant monitoring of glycemia without increasing body weight, with no risk of hypoglycemia, with no negative ...
T. V. Saprina, Ye. S. Timokhina, N. N. Musina, T. S. Prokhorenko, L. A. Tashireva, O. K. Goncharevich   +5 more
doaj   +1 more source

GIP-overexpressing mice demonstrate reduced diet-induced obesity and steatosis, and improved glucose homeostasis. [PDF]

PLoS ONE, 2012
Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that potentiates glucose-stimulated insulin secretion during a meal. Since GIP has also been shown to exert β-cell prosurvival and adipocyte lipogenic effects in rodents ...
Su-Jin Kim, Cuilan Nian, Subashini Karunakaran, Susanne M Clee, Carlos M Isales, Christopher H S McIntosh   +5 more
doaj   +1 more source

CGC/saturation approach: soft interaction at the LHC energies

, 2017
In this paper we demonstrate that our model which is based on the CGC/saturation approach, is able to describe the soft interaction collisions including the new TOTEM prelimenary data at 13 TeV.
Gotsman, E., Levin, E., Potashnikova, I.
core   +2 more sources

Detailed optical and near-infrared polarimetry, spectroscopy and broadband photometry of the afterglow of GRB 091018: Polarisation evolution [PDF]

, 2012
[Abridged] A number of phenomena have been observed in GRB afterglows that defy explanation by simple versions of the standard fireball model, leading to a variety of new models.
A. de Ugarte Postigo, A. Gomboc, A. J. Levan, A. J. van der Horst, A. Melandri, A. Rossi, A. Rowlinson, Alard, Barth, Berger, Bersier, Bersier, Björnsson, Bloom, Bloom, Burenin, C. G. Mundell, C. Guidorzi, C. Kouveliotou, Cardelli, Chandrasekhar, Costa, Covino, Curran, Curran, Cushing, E. Palazzi, E. Rol, Evans, Fossati, Fox, Frail, Gehrels, Gehrels, Ghisellini, Goldoni, Gorosabel, Granot, Granot, Greiner, Greiner, Greiner, Gruzinov, Gruzinov, Holland, I. A. Steele, J. Gorosabel, J. Greiner, J. Hjorth, J. P. U. Fynbo, Joos, K. Wiersema, Kennicutt, Klose, Kocevski, Kouveliotou, Krühler, Krühler, L. Kaper, Lazzati, Lazzati, Lazzati, Lipkin, Martin, Martin, Masetti, Matheson, Matsumiya, Mirabal, Mundell, Mészáros, Mészáros, N. R. Tanvir, Nousek, P. A. Curran, P. A. Evans, P. Goldoni, P. T. O'Brien, Pandey, Patat, Piran, R. A. M. J. Wijers, R. Filgas, R. L. C. Starling, Racusin, Rhoads, Rhoads, Rol, Roming, Rossi, S. Covino, S. D. Vergani, S. Klose, S. Kobayashi, Sagiv, Sari, Sari, Sato, Savaglio, Schady, Serkowski, Serkowski, Simmons, Sparks, Steele, T. Krühler, Toma, Uemura, Ukwatta, V. D'Elia, Van der Horst, van Paradijs, Vlasis, Vreeswijk, Wardle, Wiersema, Wijers, Willingale, Witzel, Wu   +119 more
core   +6 more sources