Results 111 to 120 of about 27,755 (279)

New therapeutic agents for type 2 diabetes: anaesthetic considerations. A narrative review

Anaesthesiology Intensive Therapy
An increasing number of patients treated with novel antidiabetic drugs, including glucagon-like-peptide-1 receptor agonists (GLP-1RA), dual glucose-dependent insulinotropic polypeptide receptor agonists and sodium-glucose cotransporter-2 (SGLT2 ...
Oliwia Doroba, Leszek Czupryniak, Filippo Sanfilippo, Paweł Andruszkiewicz, Mateusz Zawadka   +4 more
doaj   +1 more source

Thirty-five years of R(S)UE: A retrospective

, 2007
The aim of this paper is to provide a quantitative retrospective of thirty-five years of Regional Science and Urban Economics, from Volume 1 (1971) to Volume 35 (2005).
Ottaviano, GIP, Minerva, GA
core   +1 more source

Effects of Calorie Restriction With and Without Strength, Endurance or Mixed Training on Fat‐Free and Skeletal Muscle Mass in Overweight or Obese Individuals—A Systematic Review With Pairwise Meta‐Analysis and Network Meta‐Analysis of Randomized Controlled Studies

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Calorie restriction (CR) reduces both fat mass and fat‐free mass (FFM), particularly skeletal muscle mass (SMM), which is essential for cardiometabolic health and preventing frailty. This study compares CR alone versus CR plus exercise (EX) on FFM and SMM in overweight/obese patients and examines the effects of different training modes ...
Magdalena Deller, Jan Weiershaus, Steffen Held, Christian Brinkmann   +3 more
wiley   +1 more source

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano, Line L. Haurum, Christine R. Schwarz, Francesca Porcellati, Andreas Andersen   +4 more
wiley   +1 more source

Dietary Strategies and Nutritional Management in Patients Receiving GLP-1 and Dual GIP/GLP-1 Receptor Agonists as Adjuncts to Lifestyle Interventions: A Systematic Review of Randomised Clinical Trials. [PDF]

Diabetes Obes Metab
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and dual GIP/GLP‐1 RAs are widely used to manage obesity, prediabetes and type 2 diabetes, typically in combination with lifestyle interventions. Their nutritional implications, however, remain unclear.
de Paulo RS, Bonifácio DB, de Carvalho MHL, Bressan J.   +3 more
europepmc   +2 more sources

Islet adaptation in GIP receptor knockout mice

, 2019
Glucose-dependent insulinotropic polypeptide (GIP) receptor knockout (KO) mice are tools for studying GIP physiology. Previous results have demonstrated that these mice have impaired insulin response to oral glucose.
Seino, Yutaka, Yamada, Yuchiro, Ahrén, Bo   +2 more
core   +1 more source

Dose–Response Effect of Glucagon on Glucose, Beta‐Cell Secretion and Metabolism in Healthy Individuals

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Glucagon is a key regulator of glucose and energy metabolism, yet the dose–response effects of glucagon on markers of metabolism in humans are not fully characterised. We investigated the dose‐dependent effects of glucagon on glucose metabolism, β‐cell secretion and markers of hepatic metabolism in healthy adults.
Sophie Betty Brock, Nina Lerberg Hansen, Elvar Már Sturlaugsson Jóhönnuson, Sasha Alexandra Sampson Kjeldsen, Nicolai J. Wewer Albrechtsen   +4 more
wiley   +1 more source

Mechanism of Cancer Growth Suppression of Alpha-Fetoprotein Derived Growth Inhibitory Peptides (GIP): Comparison of GIP-34 versus GIP-8 (AFPep). Updates and Prospects

, 2011
The Alpha-fetoprotein (AFP) derived Growth Inhibitory Peptide (GIP) is a 34-amino acid segment of the full-length human AFP molecule that inhibits tumor growth and metastasis. The GIP-34 and its carboxy-terminal 8-mer segment, termed GIP-8, were found to
Gerald Mizejewski, Gerald J. Mizejewski
core   +1 more source

Acute GIP and GLP‐1 Administration Exerts Differential Metabolic Effects in Totally Pancreatectomised Individuals

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims While being recognised for stimulating pancreatic insulin secretion, GIP and GLP‐1 exert various extrapancreatic effects relevant in the context of incretin‐based therapies. Here, we evaluated the extrapancreatic effects of GIP and GLP‐1, separately and combined, on postprandial physiology in totally pancreatectomised individuals ...
Liva S. L. Krogh, Maja B. Hansen, Natasha C. Bergmann, Carsten P. Hansen, Bolette Hartmann, Jens J. Holst, Filip K. Knop, Asger B. Lund, Lærke S. Gasbjerg   +8 more
wiley   +1 more source

Induction of GIP expression by nutrients.

, 2015
GIP mRNA in tissue and protein in supernatant were examined in cultured jejunum tissues of chow-fed mice after nutrient treatment for 2 hrs. A. GIP mRNA in the tissue. B. GIP peptide in the culture supernatant. The concentrations of nutrients are glucose
Nigel Irwin (484463), Jiaqiang Zhou (782710), Hans-Rudolf Berthoud (289159), Zheng Hao (289156), Jianping Ye (257861)   +4 more
core   +1 more source