Results 81 to 90 of about 74,465 (332)
The incretin system in healthy humans: The role of GIP and GLP-1.
Metabolism: Clinical and Experimental, 2019 The incretin effect, the amplification of insulin secretion occurring when glucose is taken in orally as compared to infused intravenously, is one of the factors that help the body to tolerate carbohydrate/glucose ingestion.
J. Holst
semanticscholar +1 more source
Vaccination against GIP for the treatment of obesity. [PDF]
PLoS ONE, 2008 BACKGROUND: According to the WHO, more than 1 billion people worldwide are overweight and at risk of developing chronic illnesses, including cardiovascular disease, type 2 diabetes, hypertension and stroke. Current therapies show limited efficacy and are
Alma Fulurija +6 more
doaj +1 more source
Reinforcement learning for efficient network penetration testing [PDF]
, 2019 Penetration testing (also known as pentesting or PT) is a common practice for actively assessing the defenses of a computer network by planning and executing all possible attacks to discover and exploit existing vulnerabilities.
Chen, T., Ghanem, M.
core +3 more sources
Food Safety and Health, EarlyView.Heat‐stressed soybeans adapt to elevated temperatures through coordinate regulation of destructive and protective protein expression ‐ suppressing detrimental proteins while enhancing beneficial ones. ABSTRACT Soybean represents the largest imported agricultural product in China. Imported soybeans are typically transported via maritime shipping. During
Pengdi Ding +5 more
wiley +1 more source
Nontrivial critical fixed point for replica-symmetry-breaking transitions
, 2017 The transformation of the free-energy landscape from smooth to hierarchical is one of the richest features of mean-field disordered systems. A well-studied example is the de Almeida-Thouless transition for spin glasses in a magnetic field, and a similar ...
Charbonneau, Patrick, Yaida, Sho
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Food Safety and Health, EarlyView.Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar +10 more
wiley +1 more source
Molecular Metabolism, 2018 Objective: The incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic peptide) are secreted by the gut after food intake leading to pancreatic insulin secretion and glucose lowering. Beyond its role in glucose control,
Florian Kahles +13 more
doaj +1 more source
EJNMMI Research, 2023 Background Brain metastases (BM) are the most frequent malignant brain tumors. The aim of this study was to characterize the tumor microenvironment (TME) of BM and particularly hypoxia and redox state, known to play a role in tumor growth and treatment ...
Jade Fantin +13 more
doaj +1 more source
Import pathways of precursor proteins into mitochondria [PDF]
, 1988 The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Neupert, Walter +4 more
core
Protein sorting to mitochondria [PDF]
, 1990 According to the endosymbiont hypothesis, mitochondria have lost the autonomy of their prokaryotic ancestors. They have to import most of their proteins from the cytosol because the mitochondrial genome codes for only a small percentage of the ...
Hartl, Franz-Ulrich, Neupert, Walter
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