Results 61 to 70 of about 36,022 (296)

Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors

open access: yes, 2016
BACKGROUND AND PURPOSE: Specific high potent receptor antagonists are valuable tools when evaluating animal and human physiology. Within the glucose-dependent insulinotropic polypeptide (GIP) system, considerable attention has been given to the presumed ...
Christensen, M   +7 more
core   +1 more source

Vaccination against GIP for the treatment of obesity. [PDF]

open access: yesPLoS ONE, 2008
BACKGROUND: According to the WHO, more than 1 billion people worldwide are overweight and at risk of developing chronic illnesses, including cardiovascular disease, type 2 diabetes, hypertension and stroke. Current therapies show limited efficacy and are
Alma Fulurija   +6 more
doaj   +1 more source

The Far Right Honeytrap: Georgian Media and the Mediagenic Far Right [PDF]

open access: yes, 2020
The recent wave of far-right mobilization across the globe, including Georgia, naturally attracts wide media attention. Although the interrelation of the media and the far right, especially in the Georgian context, remains under-researched, evidence from
Gelashvili, Tamta
core  

Economic evaluations of antiobesity medications: A systematic literature review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković   +5 more
wiley   +1 more source

The isolation and sequencing of human gastric inhibitory peptide (GIP) [PDF]

open access: yes, 1984
Human GIP 1–42 and fragments of human GIP corresponding to GIP 10–42, GIP 11–42, and GIP 17–42 were isolated from acid-ethanol extracts of human small intestines with the aid of an anti-GIP serum specific for the extreme C-terminal portion of the GIP ...
Alister J. Moody   +5 more
core   +1 more source

Digital Transformation and Environmental Pillar of ESG‐Based Performance Under Financing Constraints: The Mediating Role of Green Innovation in Chinese Listed Firms

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study builds upon existing work that links digital transformation (DT), financing constraints (FC), green innovation (GI), and firms' environmental pillar of ESG‐based performance (SP(E)), and further examines whether DT supports SP(E) through GI under FC.
Jiayang Cheng   +4 more
wiley   +1 more source

Recent advances of GIP and future horizons

open access: yes, 2020
Recently GIP-GLP-1 co-agonists with powerful effects on glycemic control and body weight in patients with type 2 diabetes have been described. While such effects are the expected ones from a glucagonlike peptide-1 receptor agonist, similar contributions ...
Holst, Jens Juul   +1 more
core   +1 more source

GIP receptor:Expression in neuroendocrine tumours, internalization, signalling from endosomes and structure-function relationship studies [PDF]

open access: yes, 2019
GIP is well known as a peptide regulating metabolic functions. In this review paper, we summarize a series of data on GIP receptor (GIPR). First, expression study of GIPR in human neuroendocrine tumours showed a very high incidence (nearly 100%) and a ...
Reubi, Jean Claude   +6 more
core   +1 more source

Serum and expression profiles of glucose-dependent insulinotropic polypeptide in correlation with cardiometabolic risk factors among patients with systemic lupus erythematosus

open access: yesThe Egyptian Journal of Internal Medicine, 2019
Background Premature atherosclerosis has been recognized as a major co-morbid condition in systemic lupus erythematosus (SLE). Glucose-dependent insulinotropic polypeptide (GIP) is closely related to cardiovascular (CV) risk factors. We aimed to evaluate
Nearmeen M Rashad   +4 more
doaj   +1 more source

Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation. [PDF]

open access: yesPLoS ONE, 2013
Gastric inhibitory polypeptide (GIP) is a gut derived peptide with multiple emerging physiological actions. Effects of pregnancy and lactation on GIP secretion and related gene expression were studied in Wistar rats.
R Charlotte Moffett   +3 more
doaj   +1 more source

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