Results 111 to 120 of about 5,036 (195)

Gating of GIRK Channels [PDF]

Neuron, 2003
Sadja, Rona, Alagem, Noga, Reuveny, Eitan   +2 more
openaire   +1 more source

Association of Rgs7/Gβ5 complexes with girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons

, 2013
In the hippocampus, signaling through G protein-coupled receptors is modulated by Regulators of G protein signaling (Rgs) proteins, which act to stimulate the rate of GTP hydrolysis, and consequently, G protein inactivation.
Martemyanov, K.A., Fajardo-Serrano, A., Shigemoto, R., Watanabe, M., Wickman, K., Young, D., Luján, R., Wydeven, N.   +7 more
core   +1 more source

Does Ethanol Activate G-Protein Coupled Inwardly Rectifying K+ Channels?

, 2009
G-protein coupled inwardly rectifying K+ (GIRK) channels have been reported to be targets of ethanol actions. We investigated if ethanol affects native GIRK channels in rat brain tissues at clinically relevant concentrations using brain slices containing
邱麗珠;莊廣傑;范書懷;郝政鴻;鄭仁坤, CHIOU, LIH-CHU;CHUANG, KUANG-CHIEH;FAN, SHU-HUAI;HOW, CHENG-HUNG;CHENG, JEN-KUN   +1 more
core  

Inhibitory signaling and reward: the role of GIRK channels in the mesocorticolimbic dopamine system [PDF]

, 2015
University of Minnesota Ph.D. dissertation. December 2015. Major: Pharmacology. Advisor: Kevin Wickman. 1 computer file (PDF); x, 121 pages.Drug abuse is a critical global problem and given the current lack of efficacious pharmacotherapies to treat ...
Kotecki, Lydia
core  

Untersuchungen zur funktionellen Expression von GIRK-Kanälen in der Nebennierenrinde der Ratte und in der H295R-Zelllinie

, 2016
GIRK-Kanäle sollen für das Ruhepotential von Glomerulosazellen eine Rolle spielen. Es fehlen bislang jedoch Untersuchungen zur Expression und Funktionalität.
Krapp, Jan Henrik (Dr. med.)
core   +1 more source

G protein-coupled inwardly-rectifying potassium (GIRK) chanels mediate entrainment of circadian rhythms [PDF]

, 2015
Circadian rhythms are 24-hour cycles in biological and behavioral processes. These cycles enable an organism to predict changes in its environment, like changes in food availability and seasonality. Although endogenously driven, these rhythms can entrain
Hablitz, Lauren Marie
core  

Molecular mechanisms of Kir channel gating. [PDF]

Biochem Soc Trans
Bysack A, Raghuraman H.
europepmc   +1 more source

PKC isoform-specific targeting of the phosphorylation site Serine¹⁹¹ in the GIRK4 subunit induces receptor-dependent modulation of GIRK channel activity. [PDF]

Pflugers Arch
Inderwiedenstraße L, Kienitz MC.
europepmc   +1 more source

The Identification of Girk Channel Domains that Facilitate Rapid and Efficient Coupling to G Protein- Coupled Receptors

, 2011
Additional contributors: Nicole Wydeven; Kevin Wickman (faculty mentor)G protein-gated inwardly rectifying potassium (GIRK or Kir3) channels constitute one subfamily of potassium-selective ion channels that regulate neuronal activity and heart rate ...
Young, Daniele
core  

Paracrine inhibition via G protein inwardly rectifying potassium channels regulates glucagon secretion from human pancreatic alpha cells. [PDF]

Cell Rep
Panzer JK, Lang AL, Levi NJ, Garcia PA, Barro-Soria R, Caicedo A.   +5 more
europepmc   +1 more source